Module number 986




Database revision : gnsdb28.10
Date : Tue Feb 25 17:21:04 2003
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Cond664:mec1_plus_gamma_20_min\n Cond826:tlc1_Expt.1_Passage_7\n mYPR015C:Unknown ,, Unknown\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond836:tlc1_Expt.2_Passage_8\n mARG3:Sixth step in arginine biosynthesis,ornithine carbamoyltrans\nferase,Arginine requiring\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n Cond654:wt_plus_gamma_45_min\n mMSC1:Meiotic Sister-Chromatid recombination,,\n Cond824:tlc1_Expt.1_Passage_5\n Cond679:DES460(wt)_vs._DES459(mec1)_genomic_DNA_comparison\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Cond363:dtt_015_min_dtt-2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond4:afg3(haploid)\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond657:wt_plus_gamma_120_min\n Cond834:tlc1_Expt.2_Passage_6\n mECM4:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYBL064C:Unknown ,, Unknown\n mGTT1:Glutathione Transferase,glutathione transferase,Null mutant \nis viable, heat shock sensitive at stationary phase\n Cond364:dtt_030_min__dtt-2\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond822:tlc1_Expt.1_Passage_3\n Cond656:wt_plus_gamma_90_min\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond344:constant_0.32_mM_H2O2_(160_min)_redo\n Cond231:yhr031c\n Cond638:DES460_+_0.02%_MMS_-_90_min\n mPEP4:vacuolar proteinase A,vacuolar proteinase A,Null mutant is v\niable, proteinase deficient, phosphatase deficient; pep4 mut\nants exhibit a 60-70% reduction in total protein degradation\n during sporulation\n Cond635:DES460_+_0.02%_MMS_-_30_min\n mDDR48:DNA damage inducible; implicated in the production or recove\nry of mutations,contains >35 repeats of the amino acid seque\nnce NNNDSYGS , flocculent specific protein,Null mutant is vi\nable, displays reduced spontaneous mutation rate\n mYDL124W:Unknown ,, Unknown\n Cond341:constant_0.32_mM_H2O2_(80_min)_redo\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond827:tlc1_Expt.1_Passage_8\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n mYDR015C:Unknown ,, Unknown\n mYPS6:Gpi-anchored aspartic protease (Yapsin 6),GPI-anchored aspar\ntic protease,\n mNUD1:Spindle pole body protein,,Null mutant is inviable\n mSMF3:Putative metal transporter, Nramp homolog, homolog of SMF1 a\nnd SMF2,Nramp homolog , SMF1 and SMF2 homolog , metal transp\norter (putative),Viable\n mYJL161W:Unknown ,, Unknown\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYMR173W-A:Unknown ,, Unknown\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond825:tlc1_Expt.1_Passage_6\n Cond835:tlc1_Expt.2_Passage_7\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mTIS11:Zinc finger containing homolog of mammalian TIS11, glucose r\nepressible gene,,Null mutant is viable but alters metabolism\n that is reflected by a pH change on YPD plates.\n Cond877:MMS\n Cond293:HU\n Cond132:rnr1(haploid**9)\n mAFR1:coordinates regulation of alpha-factor receptor signalling a\nnd induction of morphogenesis during conjugation,cytoskeleta\nl protein , similar to arrestins,defect in alpha-factor-stim\nulated morphogenesis\n Cond342:constant_0.32_mM_H2O2_(100_min)_redo\n Cond823:tlc1_Expt.1_Passage_4\n mAHP1:alkyl hydroperoxide reductase,alkyl hydroperoxide reductase,\nhypersensitive to tert-butyl hydroperoxide\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond653:wt_plus_gamma_30_min\n mYNL115C:Unknown ,, Unknown\n Cond833:tlc1_Expt.2_Passage_5\n mYLR327C:Unknown ,, Unknown\n mRAD51:Involved in processing ds breaks, synaptonemal complex forma\ntion, meiotic gene conversion and reciprocal recombination.,\nRad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsi\ns (independently of ZIP1 and DMC1), and interacts with Rad52\np and Rad55p; human Rad51p homolog interacts with Brca2 prot\nein which has been implicated in causing breast cancer , Rec\nA homolog,Null mutant is viable; accumulates meiosis-specifi\nc double strand breaks at a recombination hotspot and reduce\ns the formation of physical recombinants and processed doubl\ne strand breaks with long heterogeneous tails; rad51 mutants\n are also defective for X-ray damage repair and gene convers\nions; rad51 rad27 mutants are inviable.\n mYLR149C:Unknown ,, Unknown\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond831:tlc1_Expt.2_Passage_3\n mYEL047C:Unknown ,, Unknown\n Cond828:tlc1_Expt.1_Passage_9\n mYBL073W:Unknown ,, Unknown\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n mRNR2:small subunit of ribonucleotide reductase,ribonucleotide red\nuctase subunit , ribonucleotide reductase, small (R2) subuni\nt,Null mutant is inviable\n Cond343:constant_0.32_mM_H2O2_(120_min)_redo\n mFIS1:Involved in mitochondrial division,outer mitochondrial membr\nane protein required to localize Dnm1p and Mdv1p during mito\nchondrial division,Null mutant is viable, mitochondrial fiss\nion blocked, mitochondrial membranes form nets\n Cond650:wt_plus_gamma_5_min\n mRNR4:ribonucleotide reductase, small subunit (alt),ribonucleotide\n reductase, small (R2) subunit,Null mutant is inviable in th\ne W303 strain background, but viable and sick in another (Wa\nng et al.[1997] Mol. Cell Biol.17:6114-6121). An rnr4 mutan\nt is resistant to 40 ug/ml benomyl, supersensitive to hydrox\nyurea (HU)[dead at 0.005M HU], and cold sensitive [cells arr\nest at 14 deg. C. with a large bud and short mitotic spindle\n].\n mYPR174C:Unknown ,, Unknown\n Cond655:wt_plus_gamma_60_min\n mGPH1:Releases glucose-1-phosphate from glycogen,glycogen phosphor\nylase,Null mutant is viable; haploid cells contain higher le\nvels of intracellular glycogen\n mPLM2:Plasmid Maintenance,,Null mutant is viable and shows 2mu-m p\nlasmid instability\n Cond837:tlc1_Expt.2_Passage_9__\n Cond652:wt_plus_gamma_20_min\n mRNR4 mRNR2
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Computational Genomics Lab, Tel-Aviv uniresity