Module number 966




Database revision : gnsdb28.10
Date : Tue Feb 25 17:17:25 2003
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Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond217:yer050c\n Cond397:Nitrogen_Depletion_2_h\n Cond3:aep2\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond396:Nitrogen_Depletion_1_h\n Cond225:yhl013c\n Cond104:npr2\n mAQY2:aquaporin water channel in yeast,MIP family member , aquapor\nin (putative),\n Cond45:ecm1(**3)\n mSTR3:Sulfur TRansfer,cystathionine beta-lyase,Null mutant is viab\nle but unable to turn cysteine into homocysteine. No growth \nwhen supplied with cystathionine.\n mARG8:Acetylornithine aminotransferase,acetylornithine aminotransf\nerase,Arginine requiring\n Cond29:clb2\n Cond130:rml2(**13)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond263:ymr269w\n Cond730:hda1\n mYNL276C:Unknown ,, Unknown\n Cond190:vps8\n Cond19:bub3(**2,8,13)\n Cond90:jnm1\n Cond112:pep12\n Cond967:swi1,_YPD_(c)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond391:aa_starv_1_h\n mFRM2:Protein involved in the integration of lipid signaling pathw\nays with cellular homeostatis,,Null mutant is viable and sen\nsitive to arachidonic acid\n Cond393:aa_starv_4_h\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond966:swi1,_YPD_(a)\n Cond184:ubr1\n Cond395:Nitrogen_Depletion_30_min.\n mYCR007C:Unknown ,, Unknown\n mYAL046C:Unknown ,, Unknown\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n mYCR043C:Unknown ,, Unknown\n Cond216:yer044c(haploid)\n Cond189:vps21\n mMET10:subunit of assimilatory sulfite reductase,assimilatory sulfi\nte reductase subunit,Null mutant is viable, and is a methion\nine auxotroph\n Cond176:swi5\n Cond524:ste5D/wtlog10(intensity)\n Cond226:yhl029c\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCPR4:cyclophilin homolog,cyclophilin , peptidyl-prolyl cis-trans \nisomerase (PPIase) , cyclophilin , peptidyl-prolyl cis-trans\n isomerase (PPIase),suppressor of cdc65\n mMET14:adenylylsulfate kinase,adenylylsulfate kinase,Null mutant is\n viable, and is a methionine auxotroph\n mMET17:O-Acetylhomoserine-O-Acetylserine Sulfhydralase,O-acetylhomo\nserine (thiol)-lyase,Null mutant is viable, methionine auxot\nroph, becomes darkly pigmented in the presence of Pb2+ ions;\n resistant to methylmercury and exhibits increased levels of\n H2S\n mLEU1:leucine biosynthesis,isopropylmalate isomerase,Leucine requi\nring\n Cond144:rtg1\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae.  Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond139:rpl8a\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond558:alpha49\n Cond171:ste24(haploid)\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond175:swi4\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYDL241W:Unknown ,, Unknown\n Cond27:ckb2\n mRAD18:Zn finger protein, putative ATPase,ATPase (putative) , zinc \nfinger protein,radiation sensitive\n Cond73:gyp1\n Cond394:aa_starv_6_h\n Cond398:Nitrogen_Depletion_4_h\n mECM17:ExtraCellular Mutant,sulfite reductase (putative),loss of fu\nnction mutants are methionine requiring and sensitive to the\n cell wall perturbing agent calcoflour white.\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n mISU1:Iron-sulfur cluster nifU-like protein,,Null mutant is viable\n on YPD at 30 degrees C, and is synthetically lethal with is\nu2 null.\n Cond294:Itraconazole\n mYPR123C:Unknown ,, Unknown\n mMET3:ATP sulfurylase,ATP sulfurylase,Null mutant is viable, and i\ns a methionine auxotroph\n mYLR302C:Unknown ,, Unknown\n mMET6:vitamin B12-(cobalamin)-independent isozyme of methionine sy\nnthase (also called N5-methyltetrahydrofolate homocysteine m\nethyltransferase or 5-methyltetrahydropteroyl triglutamate h\nomocysteine methyltransferase),vitamin B12-(cobalamin)-indep\nendent isozyme of methionine synthase (also called N5-methyl\ntetrahydrofolate homocysteine methyltransferase or 5-methylt\netrahydropteroyl triglutamate homocysteine methyltransferase\n),Null mutant is viable, and is a methionine auxotroph\n Cond968:swi1,_YPD_(d)\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n  Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond173:ste5(haploid)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond392:aa_starv_2_h\n Cond135:rpl20a\n mYIR042C:Unknown ,, Unknown\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n

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Computational Genomics Lab, Tel-Aviv uniresity