Module number 953




Database revision : gnsdb28.10
Date : Tue Feb 25 17:15:29 2003
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mURA10:Fifth step in pyrimidine bio5,orotate phosphoribosyltransfer\nase 2,Null mutant is viable\n Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond277:AUR1(tetpromoter)\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond221:yer083c\n mHOM2:threonine and methionine pathway,aspartic beta semi-aldehyde\n dehydrogenase,Homoserine requiring\n Cond104:npr2\n mMCH1:Unknown ,, Unknown\n Cond260:ymr237w\n mSTR2:Sulfur TRansfer,cystathionine gamma-synthase,Null mutant is \nviable but unable to turn cysteine into homocysteine. Grows \nwhen supplied with cystathionine.\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond29:clb2\n mYAT2:The Yat2p protein shows significant homology with the known \ncarnitine acetyltransferase associated with the outer-mitoch\nondrial membrane, Yat1p, and also functions as a carnitine a\ncetyltransferase.,carnitine acetyltransferase,Null: viable. \nOther phenotypes: The cit2yat2 double mutant does not grow o\nn ethanol, glycerol and acetate in the presence of carnitine\n.\n Cond13:ase1(**12)\n mYOR192C:Unknown ,, Unknown\n Cond224:CMD1(tetpromoter)\n Cond730:hda1\n Cond190:vps8\n Cond244:ymr010w\n mSDT1:suppressor of deletion of TFIIS,,null mutant is viable, but \nis sensitive to 6-azauracil\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n Cond90:jnm1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n Cond53:erg2\n mYDR250C:Unknown ,, Unknown\n mFRM2:Protein involved in the integration of lipid signaling pathw\nays with cellular homeostatis,,Null mutant is viable and sen\nsitive to arachidonic acid\n mYPL035C:Unknown ,, Unknown\n Cond480:WT+/-100mM3AT(SetA)(R491)\n mYNR069C:Unknown ,, Unknown\n Cond184:ubr1\n Cond123:rad57\n Cond6:anp1\n Cond298:Terbinafine\n Cond279:ERG11(tetpromoter)\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mNIT1:nitrilase,nitrilase,\n Cond201:yel008w\n Cond229:yhr011w(**14)\n Cond216:yer044c(haploid)\n mPEX21:Peroxin; Pex18p and Pex21p are partially functionally redund\nant.,peroxin,Null mutant is viable.\n mSER1:phosphoserine transaminase,phosphoserine transaminase,Null m\nutant is viable, serine-requiring\n Cond86:imp2'(**12)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n mICY2:Interacting with the cytoskeleton,,\n Cond176:swi5\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond226:yhl029c\n Cond194:yap1\n Cond287:2-deoxy-D-glucose\n Cond478:WT+/-10mM3AT(R491)\n Cond128:rgt1\n mTRP2:anthranilate synthase Component I,anthranilate synthase comp\nonent I,tryptophan requiring\n Cond145:rts1\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond144:rtg1\n Cond150:sbh2\n Cond71:gln3\n mUGA3:Transcriptional activator necessary for gamma-aminobutyrate \n(GABA)-dependent induction of GABA genes (such as UGA1, UGA2\n, UGA4),zinc finger transcription factor of the Zn(2)-Cys(6)\n binuclear cluster domain type,Null mutant is viable but exh\nibits defects in activation of UGA1 and UGA4.\n Cond43:dot4\n mYOR186W:Unknown ,, Unknown\n mYIL165C:Unknown ,, Unknown\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond481:WT+/-100mM3AT(SetB)(491)\n mYKL033W-A:Unknown ,, Unknown\n Cond233:yhr039c\n mILV1:threonine deaminase,threonine deaminase,Isoleucine-plus-vali\nne requiring\n Cond68:gas1\n Cond171:ste24(haploid)\n Cond143:rrp6\n Cond26:cka2\n Cond175:swi4\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYJR111C:Unknown ,, Unknown\n Cond250:ymr031w-a\n Cond153:sgs1\n Cond27:ckb2\n Cond73:gyp1\n Cond731:hda1 \n mBIO3:biotin biosynthesis,7,8-diamino-pelargonic acid aminotransfe\nrase (DAPA) aminotransferase,\n Cond162:spf1\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond294:Itraconazole\n Cond25:cin5\n Cond159:sir3\n Cond295:Lovastatin\n mIDP1:Mitochondrial form of NADP-specific isocitrate dehydrogenase\n,NADP-dependent isocitrate dehydrogenase,Null mutant is viab\nle\n Cond299:Tunicamycin\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond160:sir4\n Cond135:rpl20a\n mYDR278C:Unknown ,, Unknown\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n
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Computational Genomics Lab, Tel-Aviv uniresity