Module number 911




Database revision : gnsdb28.10
Date : Tue Feb 25 17:09:30 2003
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Cond796:Ca5'\n mSOF1:involved in rRNA processing,56 kDa nucleolar snRNP protein t\nhat shows homology to beta subunits of G-proteins and the sp\nlicing factor Prp4,Null mutant is inviable. sof1-56, a domin\nant suppressor of nop1 mutants can restore growth and pre-RN\nA processing at 35 degrees C. In vivo depletion of SOF1 lead\ns to impaired pre-rRNA processing and inhibition of 18S rRNA\n production.\n Cond399:Nitrogen_Depletion_8_h\n mYDR413C:Unknown ,, Unknown\n Cond798:Ca30'\n Cond791:Sorbitol_30'\n Cond432:YPD_stationary_phase_22_d_ypd-1\n mYOR145C:Unknown ,, Unknown\n Cond410:diauxic_shift_timecourse_18.5_h\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n mFPR4:Homolog of homolog of the nucleolar FKBP, Fpr3,peptidyl-prol\nyl cis-trans isomerase (PPIase),Null mutant is viable\n mPUF6:member of the PUF protein family,,\n Cond675:MHY1_(dun1)_+_heat_20_min\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n mURA7:Last step in pyrimidine biosynthesis pathway; URA7 is very s\nimilar to URA8 CTP synthase,CTP synthase,Null mutant is viab\nle; ura7 ura8 double deletion mutants are inviable\n Cond697:gal2-gal\n Cond834:tlc1_Expt.2_Passage_6\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPA135:135 kDa subunit of RNA polymerase I,RNA polymerase I subunit\n,suppression of rpb1, cold sensitive\n mRKI1:Ribose-5-phosphate ketol-isomerase,ribose-5-phosphate ketol-\nisomerase,Null mutant is inviable\n Cond416:YPD_10_h__ypd-2\n Cond810:Na45'\n Cond637:DES460_+_0.02%_MMS_-_60_min\n mNOP12:Nucleolar Protein; isolated as a mutant exhibiting synthetic\n lethality with a nop2 ts allele.,,Null mutant is viable and\n shows slow growth and cold sensitivity\n mNOP13:Nucleolar Protein 13,,\n mRRS1:Regulator for ribosome synthesis,,Null mutant is inviable. R\nsr1p depletion causes defects in pre-rRNA processing and rib\nosome assembly. The rrs1-1 mutant exhibits reduced transcrip\ntional repression of both rRNA and ribosomal protein genes.\n mNOP14:NucleOlar Protein 14,ribosome biogenesis,lethal\n mRSA3:RiboSome Assembly,,\n mPWP1:Protein with periodic trytophan residues that resembles memb\ners of beta-transducin superfamily because of presence of WD\n-40 repeats,,Null mutants are viable but show severely retar\nded growth\n mPWP2:Eight WD-repeats with homology with G protein beta subunits \nflanked by nonhomologous N-terminal and C-terminal extension\ns,,Null mutant is inviable\n mNOP15:Nucleolar protein 15,ribosome biogenesis,\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mRPA12:A12.2 subunit of RNA polymerase I,RNA polymerase I A12.2 sub\nunit,Null mutant is viable but is temperature sensitive; syn\nthetically lethal with RPA14\n Cond318:37C_to_25C_shock_-_60_min\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond155:she4\n Cond312:Heat_Shock_015_minutes_hs-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mMAK16:putative nuclear protein,nuclear protein (putative),Null mut\nant is inviable, conditional mutants arrest at G(sub)1, are \ndeficient in maintenance of killer M1 double-stranded RNA\n mENP1:Essential nuclear protein,57 kDa protein with an apparent MW\n of 70 kDa by SDS-PAGE (putative),Null mutant is inviable\n mENP2:Unknown ,, Unknown\n Cond693:gal7+gal\n Cond569:cdc15_10\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond914:(99i2)_S150-2B_YPGL+G_NormInt\n mYOR146W:Unknown ,, Unknown\n mLOC1:Localization of mRNA,,Mutant exhibits slow growth at 30C\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mCGR1:coiled-coil growth-regulated,coiled-coil protein,Null mutant\n is inviable; CGR1 expression is down-regulated in the postd\niauxic growth phase\n mYJR070C:Unknown ,, Unknown\n mHCA4:putative RNA helicase,RNA helicase (putative),Null mutant is\n inviable. A Tn3 insertion into this gene causes hypersensit\nivity to the cell surface polymer perturbing agent calcofluo\nr white.\n mMRD1:Multiple RNA Binding Domain; essential for synthesis of the \nsmall ribosomal subunit,,Null mutant is inviable (haploid di\nvides 2-3 times)\n mNOG1:Nucleolar G-protein 1; LPG15w (working nomenclature),homolog\ns identified in human and Trypanosoma brucei , nucleolar G-p\nrotein (putative),Null mutant is inviable.\n mNOG2:Nuclear/Nucleolar GTP-binding protein 2,part of a pre-60S co\nmplex,Null: lethal. Other phenotypes: A gal1::nog2 mutant sh\nows 60S maturation defect in glucose repressive conditions.\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mYIL096C:Unknown ,, Unknown\n Cond662:mec1_plus_gamma_5_min\n mYLR435W:Unknown ,, Unknown\n mLSG1:Killer toxin REsistant,,Heterozygous diploid mutant exhibits\n haploinsufficiency K1 killer toxin resistance\n mMAK21:essential for 60s ribosome biogenesis; involved in nuclear e\nxport of pre-ribosomes,,deficient in maintenance of killer\n mRMT2:Protein Arginine Methyltransferase; R = arginine; MT = methy\nltransferase,arginine methyltransferase,Null mutant is viabl\ne\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n mSIK1:homology to microtubule binding proteins and to X90565_5.cds\n,similar to microtubule binding proteins and to X90565_5.cds\n,wild-type gene suppresses toxicity of GAL4-I-Kappa-B alpha \nin yeast\n Cond833:tlc1_Expt.2_Passage_5\n mECM16:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYGR272C:Unknown ,, Unknown\n Cond706:gal2gal80-gal\n Cond370:1.5_mM_diamide_(10_min)\n Cond571:cdc15_50\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond461:21_deg_growth_ct-1\n Cond813:Na+FK30'\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond303:Heat_Shock_20_minutes_hs-1\n mRPA34:RNA polymerase I subunit, not shared (A34.5),,Null mutant is\n viable but its RNA polymerase I lacks subunit A49 (rpa49p);\n synthetically lethal with RPA14; shows synthetic interactio\nns with DNA topoisomerase I (TPO1)\n mMRT4:mRna turnover 4,,Null mutant exhibits slow growth. ts mutat\nion results in decreased decay rates of mRNAs\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond570:cdc15_30\n mYPL146C:Unknown ,, Unknown\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Cond408:diauxic_shift_timecourse_13.5_h\n mGUA1:GMP synthase,GMP synthase,Null mutant is viable but is a gua\nnine auxotroph\n Cond11:arg5,6\n mYJR071W:Unknown ,, Unknown\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond801:CaFK15'\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n mYIL127C:Unknown ,, Unknown\n Cond316:37C_to_25C_shock_-_30_min\n Cond462:25_deg_growth_ct-1\n mTCI1:protein phosphatase Two C-Interacting protein,,\n Cond982:pho85D_10_mM_1NaPP1_\n Cond301:Heat_Shock_10_minutes_hs-1\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mBRX1:Essential nucleolar protein required for biogenesis of the 6\n0S ribosomal subunit,,inviable\n mYOR309C:Unknown ,, Unknown\n mYLR401C:Unknown ,, Unknown\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n mNEW1:This gene encodes a protein with an Q/N-rich amino terminal \ndomain that acts as a prion, termed [NU]+.,,Null mutant is v\niable\n mDUS1:tRNA dihydrouridine synthase,tRNA dihydrouridine synthase,\n mRPA43:DNA-dependent RNA polymerase I subunit A43,DNA dependent RNA\n polymerase I subunit A43,Null mutant is inviable\n Cond224:CMD1(tetpromoter)\n Cond800:CaFK5'\n mYBL028C:Unknown ,, Unknown\n mRPA49:49-kDa alpha subunit of RNA polymerase A,RNA polymerase A 49\n kDa alpha subunit,Null mutant is viable but grows slowly an\nd is temperature or cold sensitive; synthetically lethal wit\nh RPA14\n Cond745: mYOR287C:Unknown ,, Unknown\n Cond371:1.5_mM_diamide_(20_min)\n Cond377:1M_sorbitol_-_5_min\n mYNL313C:Unknown ,, Unknown\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mKRE33:Killer toxin REsistant ,,Heterozygous diploid mutant exhibit\n haploinsufficiency K1 killer toxin resistance\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond651:wt_plus_gamma_10_min\n mNUG1:NUclear GTPase,Nuclear GTPase involved in Ribosome biogenesi\ns,Null: dead.\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mKRR1:Involved in cell division and spore germination,,Null mutant\n is inviable\n Cond832:tlc1_Expt.2_Passage_4\n mEMG1:Essential for Mitotic Growth,ribosome biogenesis,Lethal\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n mNRP1:asparagine-rich protein,,\n mHMT1:hnRNP methyltransferase,arginine methyltransferase , mono- a\nnd asymmetrically dimethylating enzyme , arginine methyltran\nsferase , mono- and asymmetrically dimethylating enzyme , ar\nginine methyltransferase , mono- and asymmetrically dimethyl\nating enzyme,Null mutant is viable, hmt1 npl3-1 mutants are \ninviable\n mYLR198C:Unknown ,, Unknown\n mMAK5:Necessary for maintenance of dsRNA killer plasmids. Is predi\ncted to encode an DEAD-box RNA helicase,,deficient in mainte\nnance of killer\n Cond638:DES460_+_0.02%_MMS_-_90_min\n mNOP58:57 kDa nucleolar protein involved in the pre-rRNA processing\n steps that lead to formation of 18 S rRNA; interacts with N\nop1p,57 kDa nucleolar protein,Null mutant is inviable; in vi\nvo depletion impairs synthesis of the 40S ribosomal subunit\n Cond764:Heat_120'\n Cond635:DES460_+_0.02%_MMS_-_30_min\n mLTV1:Protein required for viability at low temperature,,\n Cond857:pm38-gtoe\n mRNT1:Ribonuclease III,ribonuclease III,Null mutant is viable, but\n very sick (Abou Elela and Ares 1998, Chanfreau et al 1998).\n mCBF5:major low affinity 55 kDa Centromere/microtubule binding pro\ntein,major low affinity 55 kDa centromere/microtubule bindin\ng protein,Null mutant is inviable\n mYEF3:contains two ABC cassettes, and binds and hydrolyses ATP,Tra\nnslation elongation factor 3 (EF-3),Null mutant is inviable\n Cond317:37C_to_25C_shock_-_45_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mHGH1:HMG1/2 homolog,,\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond419:YPD_2_d_ypd-2\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mPXR1:Unknown ,, Unknown\n Cond139:rpl8a\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mUTP4:Unknown ,, Unknown\n mUTP5:Unknown ,, Unknown\n mMIS1:mitochondrial C1-tetrahydroflate synthase,C1-tetrahydrofolat\ne synthase,Null mutant is viable, exhibits no apparent defec\nts in cell growth\n mUTP6:Unknown ,, Unknown\n mDBP2:ATP-dependent RNA helicase of DEAD box family,ATP dependent \nRNA helicase , dead box protein,Null mutant is inviable\n mDBP3:ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family,A\nTP dependent RNA helicase , dead/deah box protein CA3,Null m\nutant is viable\n mUTP8:Unknown ,, Unknown\n mUTP9:Unknown ,, Unknown\n mUTP10:Unknown ,, Unknown\n mUTP11:Unknown ,, Unknown\n Cond806:crz1/Ca15'\n mDBP7:Dead-box protein,RNA helicase (putative),Null mutant is viab\nle but shows slow growth\n mDBP8:Dead-Box Protein 8, ATP-dependent helicase involved in rRNA \nprocessing,dead box protein,Null mutant is inviable\n mUTP13:Unknown ,, Unknown\n mDBP9:Dead-Box Protein 9,,Null mutant is inviable\n mUTP14:Unknown ,, Unknown\n mUTP15:Unknown ,, Unknown\n mTRM1:N2,N2-dimethylguanosine-specific tRNA methyltransferase,N2,N\n2-dimethylguanosine-specific tRNA methyltransferase,An uncha\nracterized allele affects a specific base modification of bo\nth cytoplasmic and mitochondrial tRNA.\n mTRM2:tRNA methyltransferase,tRNA methyltransferase,\n mUTP18:Unknown ,, Unknown\n mYOR252W:Unknown ,, Unknown\n Cond811:Na60'\n mUTP19:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond707:gal4gal80-gal\n Cond324:heat_shock_33_to_37,_20_minutes\n mTRM8:Unknown ,, Unknown\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n mSAS10:Something About Silencing 10,,Null mutant is inviable; derep\nresses HMR, HML and telomeres when overexpressed\n mIMP3:Interacts With Mpp10. Imp3p is a specific component of the U\n3 snoRNP and is required for pre-18S rRNA processing. It is \nnot required for U3 snoRNA stability.,,Null mutant is inviab\nle\n mIMP4:Interacts With Mpp10. Imp4p is a specific component of the U\n3 snoRNP and is required for pre-18S rRNA processing.,,Null \nmutant is inviable\n Cond831:tlc1_Expt.2_Passage_3\n Cond815:Na+FK60'\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond968:swi1,_YPD_(d)\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n mMTR4:Dead-box family helicase required for mRNA export from nucle\nus,RNA helicase,Null mutant is inviable; a temperature-sensi\ntive mtr4 mutant accumulates poly(A)+ RNA in the nucleus at \n37 degrees\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond559:alpha56\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mRPC19:subunit common to RNA polymerases I (A) and III (C),RNA poly\nmerases I (A) and III (C) subunit,Null mutant is inviable\n Cond980:F82G_10_mM_1NaPP1\n mUTP21:Unknown ,, Unknown\n mBUD22:Hypothetical ORF,,Null mutant is viable; random budding in d\niploid null mutants\n Cond979:WT_10_mM_1NaPP1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n mGAR1:small nucleolar RNP proteins,small nucleolar RNP protein,Nul\nl mutant is inviable\n mYBR266C:Unknown ,, Unknown\n mCIC1:Nop seven associated protein 3,ribosome biogenesis,\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n mRLP24:Ribosomal Like Protein 24,part of a pre-60S complex,Null: le\nthal. Other phenotypes: A gal1::rlp24 mutant shows a 60S mat\nuration defect under glucose repressive conditions..\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mNSA1:Nop seven associated,ribosome biogenesis,\n Cond913:(99i3)_S150-2B_YPD_NormInt\n Cond761:Heat_30'\n mNSA2:Killer toxin Resistant; Nop seven associated protein 2,ribos\nome biogenesis,Heterozygous diploid mutant exhibit haploinsu\nfficiency K1 killer toxin resistance\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mAAH1:adenine aminohydrolase (adenine deaminase),adenine aminohydr\nolase (adenine deaminase),Null mutant is viable\n mSDA1:Severe Depolymerization of Actin,,Null mutant is inviable; s\nda1-1 temperature-sensitive mutants arrest with defects in t\nhe organization of the actin cytoskeleton.\n Cond315:37C_to_25C_shock_-_15_min\n mKAP123:Karyopherin of predicted MW 122.524 Da. Similar to Kap95p (Y\nLR347C) and Kap104p *YBR017C). Ran binding protein, Homolog \nof importin-beta,karyopherin beta 4,Null mutant is viable\n Cond976:F82G_1_mM_1NaPP1\n Cond467:steady_state_21_dec_C_ct-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n mBFR2:involved in protein transport step at the Brefeldin A blocks\n,,Null mutant is inviable; BFR2 overexpression can suppress \nthe growth defect of mutants blocked at the step of budding \nor docking of small vessicles en route to the Golgi\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Cond373:1.5_mM_diamide_(40_min)\n Cond822:tlc1_Expt.1_Passage_3\n mDIM1:Dimethyladenosine transferase, (rRNA(adenine-N6,N6-)-dimethy\nltransferase),reponsible for m6[2]Am6[2]A dimethylation in 3\n'-terminal loop of 18S rRNA,dimethyladenosine transferase,Nu\nll mutant is inviable\n Cond409:diauxic_shift_timecourse_15.5_h\n Cond802:CaFK30'\n Cond300:Heat_Shock_05_minutes_hs-1\n mIPI2:Unknown ,, Unknown\n mIPI3:Unknown ,, Unknown\n mNMD3:putative Upf1p-interacting protein,factor required for a lat\ne assembly step of the 60S subunit,Null mutant is inviable, \nat nonpermissive temperature, nmd3 ts mutants exhibit decrea\nsed levels of 60S subunits resulting in formation of half-me\nr polysomes; nmd3 xrn1(kem1) double mutants are inviable\n Cond814:Na+FK45'\n Cond769:Acid_80'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond335:constant_0.32_mM_H2O2_(10_min)_redo\n Cond395:Nitrogen_Depletion_30_min.\n mYKL082C:Unknown ,, Unknown\n Cond553:alpha14\n mNIP7:Nip7p is required for 60S ribosome subunit biogenesis,,Null \nmutant is inviable; in the temperature-sensitive mutant nip7\n-1, glycine 71 is replaced by aspartic acid\n mYNL114C:Unknown ,, Unknown\n mYDL062W:Unknown ,, Unknown\n Cond479:WT+/-100mM3AT(SetD)(R491)\n mYBR267W:Unknown ,, Unknown\n mYJR041C:Unknown ,, Unknown\n mYCR072C:Unknown ,, Unknown\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond361:2.5mM_DTT_180_min_dtt-1\n Cond797:Ca15'\n mLHP1:Protein homologous to human La (SS-B) autoantigen,,Null muta\nnt is viable\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mYDL063C:Unknown ,, Unknown\n mYLR413W:Unknown ,, Unknown\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYBL054W:Unknown ,, Unknown\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond818:crz1/Na30'\n Cond378:1M_sorbitol_-_15_min\n mNSR1:nuclear localization sequence binding protein,nuclear locali\nzation sequence binding protein,Null mutant is viable, shows\n severe growth defect.\n Cond358:2.5mM_DTT_060_min_dtt-1\n mRPC40:RNA polymerase III (C) subunit,RNA polymerase III subunit,Nu\nll mutant is inviable.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mLCP5:Lethal with conditional pap1 allele,,Null mutant is inviable\n; there is also a temperature sensitive mutant defective in \nrRNA processing and translation\n Cond365:dtt_060_min_dtt-2\n mPRP43:Pre-mRNA processing factor involved in disassembly of splice\nosomes after the release of mature mRNA,RNA helicase,\n Cond374:1.5_mM_diamide_(50_min)\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond959:t2_g/r_ratio\n mRCL1:protein similar to the RNA 3' terminal phosphate cyclase (RN\nA 3' terminal phosphate Cyclase-Like),,Null mutant is inviab\nle.\n Cond809:Na30'\n Cond325:29C_to_33C_-_5_minutes\n mGCD10:First identified as negative regulator of GCN4 expression,RN\nA-binding protein , translation initiation factor 3 (eIF-3) \nzeta subunit,Null mutant is inviable. There are mutants avai\nlable that show constitutive HIS4 transcription and slow gro\nwth\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond787:NaCl_45'\n mDHR2:Unknown ,, Unknown\n mDRS1:ribosome assembly,ATP dependent RNA helicase (putative),Null\n mutant is inviable; cold sensitive mutant with a deficit of\n 60S ribosomal subunits\n mYPL044C:Unknown ,, Unknown\n Cond859:ms221-30\n Cond366:dtt_120_min_dtt-2\n mRLP7:Significant sequence similarity to RPL7B, but neither can fu\nnctionally replace the other. Does not correspond to any rib\nosomal component identified so far, based on its biochemical\n features,,Null mutant is inviable\n Cond977:F82G_pho4D_1_mM_1NaPP1\n mKRI1:KRRI-Interacting protein 1,Krr1p binding protein,\n mYDR365C:Unknown ,, Unknown\n mELP2:ELongator Protein 2; 90kD subunit; has WD40 repeats,RNA poly\nmerase II Elongator subunit,Null mutant is viable but grows \nslowly and shows slow adaptation to growth on new media; ts-\n (39 C); sensitive to 1 M NaCl; zymotoxin resistant; slow gr\nowth; thermo-sensitive above 38 0C; caffeine, Calcofluor Whi\nte and 6-azauracil sensitive; G1 cell cycle delay\n Cond650:wt_plus_gamma_5_min\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYTM1:microtubule-associated protein,microtubule-associated protei\nn,\n Cond837:tlc1_Expt.2_Passage_9__\n Cond856:pm38-qtop\n mRRP12:Required for normal pre-rRNA processing,,Null: lethal.\n mNOP1:nucleolar protein, homologous to mammalian fibrillarin,nucle\nolar protein , similar to mammalian fibrillarin,Null mutant \nis inviable. Temperature-sensitive alleles exhibit various d\nefects in rRNA processing.\n mYOL124C:Unknown ,, Unknown\n mNOP2:May participate in nucleolar function during the transition \nfrom stationary phase to rapid growth,90 kDa protein homolog\nous to a human proliferation-associated nucleolar protein, p\n120,Null mutant is inviable; overexpression leads to changes\n in nucleolar morphology\n mNOP4:RNA recognition motif-containing protein,RNA binding protein\n (putative),Null mutant is inviable; conditional mutant show\ns diminished accumulation of 60S ribosomal subunits due to a\n lack of production of mature 25S rRNA from 27S precursor rR\nNA\n Cond396:Nitrogen_Depletion_1_h\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n mNOP7:Required for normal pre-rRNA processing,,Null: lethal.\n mDIP2:DOM34 Interacting Protein,,\n mYPR142C:Unknown ,, Unknown\n mYCR016W:Unknown ,, Unknown\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond552:alpha7\n Cond369:1.5_mM_diamide_(5_min)\n mSSF1:putative involvement in mating,Ssf2p homolog,Null mutant is \nviable, ssf1 ssf2 double deletion mutants are inviable. SSF1\n is a high copy suppressor of the mating defect caused by a \ntemperature sensitive G beta subunit mutation. Depletion of \nSSF gene products from growing cultures caused both an arres\nt of cell division and a significant decrease in the ability\n of cells to mate. Mating efficiency was increased by extra \ncopies of the SSF genes and decreased by elimination of the \ngene products\n Cond763:Heat_60'\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n Cond263:ymr269w\n Cond363:dtt_015_min_dtt-2\n mYVH1:nitrogen starvation-induced protein phosphatase,protein tyro\nsine phosphatase induced by nitrogen starvation,\n mECM1:putative transmembrane domain protein involved in cell wall \nbiogenesis,,A Tn3 insertion into ECM1 causes hypersensitivit\ny to the cell surface polymer perturbing agent calcofluor wh\nite.\n Cond782:Peroxide_40'\n mEBP2:EBNA1-binding protein homolog,nucleolar protein,Null mutant \nis inviable\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYPL183C:Unknown ,, Unknown\n Cond414:YPD_6_h_ypd-2\n mMPP10:Protein component of the U3 small nucleolar ribonucleoprotei\nn (snoRNP),U3 snoRNP protein,Null mutant is inviable\n Cond386:Hypo-osmotic_shock_-_30_min\n Cond967:swi1,_YPD_(c)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYNL174W:Unknown ,, Unknown\n mYNR054C:Unknown ,, Unknown\n Cond488:pho85_vs_WT\n Cond323:heat_shock_29_to_37,_20_minutes\n mRPF1:protein that localizes to the nucleolus,,\n mRPF2:Hypothetical ORF,,\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond426:YPD_stationary_phase_1_d_ypd-1\n mYOR004W:Unknown ,, Unknown\n mBCP1:Hypothetical ORF,,Null mutant is inviable\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n mYIL019W:Unknown ,, Unknown\n Cond420:YPD_3_d_ypd-2\n Cond357:2.5mM_DTT_045_min_dtt-1\n Cond379:1M_sorbitol_-_30_min\n mRRP1:involved in processing rRNA precursor species to mature rRNA\ns,,Null mutant is inviable, cannot be suppressed by srd1 mut\nations. rrp1-1 mutations are associated with temperature-sen\nsitive growth, a conditional defect in processing of 27S pre\n-rRNA to mature 25S rRNA, and a nonconditional increase in s\nensitivity to several aminoglycoside antibiotics. srd1 is an\n allele-specific suppressor of rrp1-1.\n mRRP3:Required for maturation of the 35S primary transcript of pre\n-rRNA and is required for cleavages leading to mature 18S RN\nA,,In strains where Rrp3 is depleted, 35S precursor RNA is i\nmproperly processed. Cleavage normally occurs at sites A0O, \nAl and A2, but in the Rrp3 depletion stain cleavage occurs b\netween A2 and B1.\n Cond758:Heat_0'_(A)\n mRRP5:Ribosomal RNA Processing,required for processing of pre-rRNA\n,Overexpression of RRP5 facilitates mitochondrial import of \nhydrophobic proteins; overexpression of an RRP5 mutant compl\nements the rRNA processing defect of the null alllele, but d\noes not facilitate mitochondrial import\n mYPR143W:Unknown ,, Unknown\n Cond273:yor078w\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRRP8:Hypothetical ORF,nucleolar protein required for efficient pr\nocessing of pre-rRNA at site A2; methyltransferase homolog,i\nmpaired growth at lower temperatures (19 to 130C) , defect i\nn pre-rRNA processing at site A2, synthetically lethal with \nmutants alleles of GAR1\n mYLR003C:Unknown ,, Unknown\n mATC1:interacts with AIP3, localized to the nucleus,,\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Cond321:heat_shock_21_to_37,_20_minutes\n mARX1:Unknown ,, Unknown\n mREX4:RNA EXonuclease; member of 3'->5' exonuclease family. See Mo\nser et al. 1997 Nucleic acids Res. 25:5110-5118,,\n Cond783:Peroxide_60'\n mNOC2:NucleOlar Complex 2; involved in nuclear export of pre-ribos\nomes,,\n mPUS7:Unknown ,, Unknown\n Cond762:Heat_45'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n mNOC3:NucleOlar Complex 2; involved in the nuclear export of pre-r\nibosomes,,\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Y-Stre.NaCl:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond835:tlc1_Expt.2_Passage_7\n Cond460:17_deg_growth_ct-1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n mTRM82:Unknown ,, Unknown\n Cond359:2.5mM_DTT_090_min_dtt-1\n mNAN1:Net1-Associated Nucleolar protein 1,,Null mutant is inviable\n Cond417:YPD_12_h_ypd-2\n Cond946:W303ume6_YPD\n mYJL122W:Unknown ,, Unknown\n mHPT1:enzyme involved in de novo purine biosynthesis,hypoxanthine \nguanine phosphoribosyltransferase,Null mutant is viable; mut\nants show resistance to 8-azaguanine\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n mSPB1:Suppressor of PaB1 mutant; involved in 60S ribosomal subunit\n biogenesis,methyltransferase (putative),Null mutant is invi\nable. The spb1-1 mutant is an extragenic suppressor of a pab\n1 null mutation.\n mRRB1:RiboSome Assembly 2,,Null mutant is inviable; a temperature-\nsensitive mutant has decreased free 60s ribosomal subunit.\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond360:2.5mM_DTT_120_min_dtt-1\n mHAS1:Helicase Associated with SET1,RNA-dependent helicase (putati\nve),Null mutant is inviable\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mROK1:contains domains found in the DEAD protein family of ATP-dep\nendent RNA helicases; high-copy suppressor of kem1 null muta\nnt,,Null mutant is inviable\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mERB1:conserved eukaryotic protein involved in ribosome biogenesis\n,,Null mutant is inviable.\n mYMR310C:Unknown ,, Unknown\n mBMS1:BMH1 sensitive,,Null mutant is inviable; a temperature-sensi\ntive allele exhibits a synthetic growth defect with bmh1-del\nta; the temperature-sensitive allele also exhibits diploid s\npecific bud site randomization at the semi-permissive temper\nature\n Cond699:gal4-gal\n mFYV13:Function required for Yeast Viability on toxin exposure,,Nul\nl mutant is viable but exhibits K1 killer toxin hypersensiti\nvity.\n mPPT1:serine/threonine phosphatase,,\n mYDR412W:Unknown ,, Unknown\n Cond858:pm71-30\n Cond665:mec1_plus_gamma_30_min\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mMAK5 mCIC1 mSPB1 mNOP7 mPWP2 mUTP6 mUTP18 mUTP13 mNOP1 mDHR2 mSOF1 mSIK1 mNOP2 mNOP58 mLHP1 mYDR365C mRRP1 mBFR2 mLCP5 mRPF2 mYNR054C mNOP12 mUTP5 mYJR070C mUTP15 mYDR412W mERB1 mPUF6 mNOP13 mNUG1 mNSA2 mNSA1 mPRP43 mROK1 mRRP5 mHAS1 mYTM1 mYPR143W mEBP2 mKRE33 mNOC2 mRPF1 mGAR1 mNMD3 mUTP9 mUTP10 mNAN1 mIPI2 mRPC19 mIPI3 mUTP11 mDIP2 mUTP21 mUTP14 mYOR145C mRPA12 mMRT4 mDBP7 mDRS1 mNOC3 mCBF5 mPWP1 mBRX1 mFPR4 mRLP7 mNOP15 mNOG1 mNIP7 mRPA135 mRPC40 mKRI1 mNOP4 mRPA49 mYBR267W mYJL122W
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity