Module number 895




Database revision : gnsdb28.10
Date : Tue Feb 25 17:17:32 2003
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Cond72:gpa2\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond826:tlc1_Expt.1_Passage_7\n Cond458:YP_raffinose_vs_reference_pool_car-2\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mSDH1:flavoprotein subunit of succinate dehydrogenase,succinate de\nhydrogenase flavoprotein subunit,no growth on glycerol (unab\nle to respire)\n mSDH2:Succinate dehydrogenase (ubiquinone) iron-sulfur protein sub\nunit,succinate dehydrogenase (ubiquinone) iron-sulfur protei\nn subunit,Null mutant is viable\n mSDH3:succinate dehydrogenase cytochrome b,succinate dehydrogenase\n cytochrome b,Null mutant is viable, has impaired mitochondr\nial function, fails to grow on non-fermentable carbon source\ns\n mSDH4:succinate dehydrogenase membrane anchor subunit,succinate de\nhydrogenase membrane anchor subunit,Null mutant is viable, r\netains ability to grow on rich glycerol media\n Cond407:diauxic_shift_timecourse11.5_\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond829:tlc1_Expt.2_Passage_1\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond13:ase1(**12)\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond834:tlc1_Expt.2_Passage_6\n Cond657:wt_plus_gamma_120_min\n mPBI2:Proteinase inhibitor that inhibits protease Prb1p (yscB),pro\nteinase inhibitor I2B (PBI2),Null mutant is viable but shows\n 50% elevation of protein degradation rate when cells are su\nbject to nutritional stress\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond416:YPD_10_h__ypd-2\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mTSL1:123 kD regulatory subunit of trehalose-6-phosphate synthase/\nphosphatase complex; homologous to TPS3 gene product,similar\n to TPS3 gene product , trehalose-6-phosphate synthase/phosp\nhatase complex 123 kDa regulatory subunit,Null mutant is via\nble\n Cond822:tlc1_Expt.1_Passage_3\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond409:diauxic_shift_timecourse_15.5_h\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCOX4:subunit IV of cytochrome c oxidase,cytochrome c oxidase subu\nnit IV,Null mutant is viable and unable to grow on nonfermen\ntable carbon sources\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n mCWP1:cell wall protein, involved in O and N glycosylation, accept\nor of B1-6 glucan.,cell wall mannoprotein,Null mutant is via\nble, has increased sensitivities to calcoflour white and con\ngo red\n Cond155:she4\n Cond830:tlc1_Expt.2_Passage_2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond915:(99i4)_HBY4_YPGL_NormInt\n mINH1:ATPase inhibitor,ATPase inhibitor,Null mutant is viable; exh\nibits marked ATP hydrolysis in response to the uncoupler car\nbonylcyanide-m-chlorophenylhydrazone\n Cond189:vps21\n Cond452:sucrose_vs._reference_pool_car-1\n Cond807:crz1/Ca30'\n Cond694:gal10+gal\n Cond851:15_min\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mGLC3:Glycogen branching enzyme,1,4-glucan-6-(1,4-glucano)-transfe\nrase,Null mutant is viable, glycogen deficient\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae.  Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond848:90_min\n Cond145:rts1\n Cond825:tlc1_Expt.1_Passage_6\n Cond187:vac8\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYNL274C:Unknown ,, Unknown\n Cond972:anc1\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mGLK1:Glucose phosphorylation,glucokinase,Null mutant is viable wi\nth no discernible difference from wild-type; hxk1, hxk2, glk\n1 triple null mutants are unable to grow on any sugar except\n galactose and fail to sporulate\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n Cond413:YPD_4_h_ypd-2\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond874:30min\n Cond833:tlc1_Expt.2_Passage_5\n Cond27:ckb2\n Cond706:gal2gal80-gal\n Cond370:1.5_mM_diamide_(10_min)\n SSD1.ANC1: Cond230:yhr022c\n Cond25:cin5\n Cond21:bul1\n Cond206:yel044w\n Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mQCR2:40 kDa ubiquinol cytochrome-c reductase core protein 2,40 kD\na ubiquinol cytochrome-c reductase core protein 2,Null mutan\nt is viable and grows slowly on glycerol\n Cond828:tlc1_Expt.1_Passage_9\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond570:cdc15_30\n mQCR7:ubiquinol-cytochrome c oxidoreductase subunit 7 (14 kDa),ubi\nquinol cytochrome C oxidoreductase subunit 7 (14 kDa),Null m\nutant is viable but shows no ubiquinol:cytochrome c oxidored\nuctase activity, is respiratory-deficient, and shows lowered\n levels of other subunits of complex III, such as the 11-kDa\n subunit VIII, the Rieske Fe-S protein and cytochrome b\n mQCR8:Ubiquinol cytochrome-c reductase subunit 8 (11 kDa protein),\nubiquinol cytochrome C reductase subunit 8 (11 kDa),Null mut\nant is viable\n Cond343:constant_0.32_mM_H2O2_(120_min)_redo\n Cond408:diauxic_shift_timecourse_13.5_h\n Cond160:sir4\n mCYT1:Cytochrome c1,cytochrome c1,\n mATP1:mitochondrial F1F0-ATPase alpha subunit,F1F0-ATPase alpha su\nbunit,null mutant is viable; grows slowly on fermentable car\nbon sources; exhibits delayed kinetics of protein import for\n several mitochondrial precursors\n Cond837:tlc1_Expt.2_Passage_9__\n mATP2:F(1)F(0)-ATPase complex beta subunit, mitochondrial,F(1)F(0)\n-ATPase complex beta subunit,Mutant displays a growth defect\n on glycerol\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond332:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_5_minutes\n Cond455:YP_galactose_vs_reference_pool_car-2\n Cond423:YPD_stationary_phase_4_h_ypd-1\n mATP5:Subunit 5 of the mitochondrial ATP synthase complex; homolog\nous to bovine OSCP and E. coli delta.,ATP synthase subunit 5\n , oligomycin sensitivity-conferring protein,null mutant is \nviable, but unable to grow on glycerol; exhibits high level \nof genetic instability\n Cond320:heat_shock_17_to_37,_20_minutes\n mATP7:ATP synthase d subunit,ATP synthase d subunit,glycerol minus\n phenotype; mitochondria have no detectable oligomycin-sensi\ntive ATPase activity; F1 loosely bound to the membranous por\ntion\n Cond836:tlc1_Expt.2_Passage_8\n Cond448:galactose_vs._reference_pool_car-1\n mYBL100C:Unknown ,, Unknown\n RapamycinHap.hap_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins.  Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Cond45:ecm1(**3)\n Cond301:Heat_Shock_10_minutes_hs-1\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond369:1.5_mM_diamide_(5_min)\n mPGM2:Phosphoglucomutase,phosphoglucomutase,Null mutant is viable,\n pgm1 pgm2 deletion mutants fail to grow on galactose\n Cond824:tlc1_Expt.1_Passage_5\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond447:ethanol_vs._reference_pool_car-1\n Cond15:bim1(**15)\n Cond386:Hypo-osmotic_shock_-_30_min\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond323:heat_shock_29_to_37,_20_minutes\n mYDR134C:Unknown ,, Unknown\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n Cond855:pm38-30\n Cond457:YP_mannose_vs_reference_pool_car-2\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond820:tlc1_Expt.1_Passage_1\n Cond6:anp1\n mMIR1:Product of gene unknown,,Null mutant is viable on glucose co\nntaining media, but is unable to grow on a non-fermentable c\narbon source, shows reduced levels of mitochondrial proteins\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond827:tlc1_Expt.1_Passage_8\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n Cond935:10h\n Cond449:glucose_vs._reference_pool_car-1\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n Cond151:sbp1\n RapamycinDip.dip_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins.  Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond450:mannose_vs._reference_pool__car-1\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond144:rtg1\n Cond278:CDC42(tetpromoter)\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n Cond835:tlc1_Expt.2_Passage_7\n Cond456:YP_glucose_vs_reference_pool_car-2\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n Cond417:YPD_12_h_ypd-2\n mHSP30:Protein induced by heat shock, ethanol treatment, and entry \ninto stationary phase; located in plasma membrane,,\n Cond117:pfd2(**14)\n Cond823:tlc1_Expt.1_Passage_4\n Cond415:YPD_8_h_ypd-2\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond283:KAR2(tetpromoter)\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n Cond324:heat_shock_33_to_37,_20_minutes\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n Cond411:diauxic_shift_timecourse_20.5_h\n Cond543:rst1Drst2Dtec1D/wtlog10(intensity)\n Cond831:tlc1_Expt.2_Passage_3\n Cond453:YP_ethanol_vs_reference_pool_car-2\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond428:YPD_stationary_phase_3_d_ypd-1\n

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Computational Genomics Lab, Tel-Aviv uniresity