Module number 878




Database revision : gnsdb28.10
Date : Tue Feb 25 17:14:01 2003
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mFAT2:Fatty acid transporter, very similar to FAT1,,\n Cond101:mrpl33\n Cond292:Glucosamine\n Cond102:mrt4\n Cond248:ymr030w\n mYLR179C:Unknown ,, Unknown\n mYER152C:Unknown ,, Unknown\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond130:rml2(**13)\n Cond266:ynd1\n Cond93:kre1\n Cond280:FKS1(tetpromoter)\n Cond185:ubr2\n mWWM1:Unknown ,, Unknown\n Cond140:rps24a(**9)\n mSCS2:Likely to be involved in regulating INO1 expression, suppres\nsor of a dominant nuclear mutation that is inositol-dependen\nt in the presence of choline,,Null mutant is viable but is a\nn inositol auxotroph above 34 deg.\n Cond105:nrf1\n mTRK2:membrane protein; low affinity potassium transport,low affin\nity potassium transport , membrane protein,Null mutant is vi\nable, requires added potassium; trk1 trk2 double mutants are\n viable\n Cond729:sin3\n Cond28:cla4(haploid)\n Cond81:hog1(haploid)\n Cond505:wtħ50nMaF,120minlog10(intensity)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mTHR1:homoserine kinase,homoserine kinase,Null mutant is viable, t\nhreonine auxotroph\n mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond210:yer002w\n Cond200:yel001c\n Cond245:ymr014w\n mCWP1:cell wall protein, involved in O and N glycosylation, accept\nor of B1-6 glucan.,cell wall mannoprotein,Null mutant is via\nble, has increased sensitivities to calcoflour white and con\ngo red\n Cond937:t=0\n mGSP2:maintenance of nuclear organization; homologous to mammalian\n Ran, a small nuclear GTPase of the ras superfamily,GTP-bind\ning protein , Gsp1p homolog,Null mutant is viable\n Cond285:RHO1(tetpromoter)\n mYCR050C:Unknown ,, Unknown\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYHR199C:Unknown ,, Unknown\n Cond61:fks1(haploid)\n mRMD7:Unknown ,, Unknown\n mCYC3:cytochrome c heme lyase (CCHL),cytochrome c heme lyase (CCHL\n),Cytochrome c deficiency\n Cond86:imp2'(**12)\n mCAF120:Hypothetical ORF,,Null mutant is viable\n Cond238:yml005w\n Cond273:yor078w\n Cond287:2-deoxy-D-glucose\n mPTC2:Protein phosphatase type 2C,protein phosphatase type 2C,\n mYOR084W:Unknown ,, Unknown\n Cond145:rts1\n mTRP5:tryptophan synthetase,tryptophan synthetase,Null mutant is v\niable and requires tryptophan\n Cond127:ras2(haploid)\n Cond139:rpl8a\n Cond278:CDC42(tetpromoter)\n Cond43:dot4\n mVRP1:Involved in cytoskeletal organization and cellular growth,pr\noline-rich protein verprolin,Null mutant is viable but is bo\nth temperature and pH sensitive and cannot grow on minimal m\nedium. Null mutant also exhibits depolarization of the actin\n cytoskeleton.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond134:rpl12a\n Cond58:erp2\n Cond256:ymr141c\n Cond52:erd1\n Cond26:cka2\n mIMP2':Protein involved in nucleo-mitochondrial control of maltose,\n galactose and raffinose utilization,transcription factor,Nu\nll mutant is viable, Inability to grow on maltose, galactose\n and raffinose in respiratory-deficient conditions or in the\n presence of ethidium bromide and erythromycin; leaky phenot\nype on oxidizable carbon sources: sensitivity to heat shock \nand sporulation deficiency\n mPRB1:dispensable for haploidization and sporulation, but needed f\nor full protein degradation during sporulation, and proper s\npore morphology,vacuolar protease B,Null mutant is viable, p\nrotease B deficient, has smaller spores than wild-type embed\nded in a thick matrix\n mAHP1:alkyl hydroperoxide reductase,alkyl hydroperoxide reductase,\nhypersensitive to tert-butyl hydroperoxide\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond80:hmg1(haploid)\n mACH1:Mannose-containing glycoprotein which binds concanavalin A,a\ncetyl CoA hydrolase,\n mSDS24:Similar to S. pombe SDS23, suppresses DIS2, localized to the\n nucleus,,Null mutant is viable\n Cond205:yel033w\n mPAN1:Involved in actin organization and endocytosis,,Null mutant \nis inviable; conditional mutants show arrest of translation \ninitiation, alterations in mRNA poly(A) tail lengths, and al\ntered cellular location of Mod5p\n Cond91:kim4\n mFAS2:Trifunctional enzyme,fatty acid synthase alpha subunit,Fatty\n acid synthetase deficient\n mSED1:putative cell surface glycoprotein,cell surface glycoprotein\n (putative),Null mutant is viable; during stationary phase, \nnull mutants exhibit increased sensitivity to Zymolyase.\n Cond283:KAR2(tetpromoter)\n Cond474:gcn4D+/-100mM3AT(KNY124)\n Cond103:msu1\n mLGE1:Unknown ,, Unknown\n mYER119C:Unknown ,, Unknown\n mTEF4:Translation elongation factor EF-1gamma,translation elongati\non factor EF-1gamma,\n mYCR051W:Unknown ,, Unknown\n mCAR2:ornithine aminotransferase,ornithine aminotransferase,Catabo\nlism of arginine defective\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond161:sod1(haploid)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n
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Computational Genomics Lab, Tel-Aviv uniresity