Module number 876




Database revision : gnsdb28.10
Date : Tue Feb 25 17:13:56 2003
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mYPR109W:Unknown ,, Unknown\n mHSP104:involved in thermal and ethanol tolerance, inheritance of [P\nSI+], and reactivation of mRNA splicing after heat shock,hea\nt shock protein 104,Null mutant is viable and defective in i\nnduced thermotolerance\n mFIL1:Putative mitochondrial ribosome recycling factor,mitochondri\nal ribosome recycling factor (putative),Null mutant is viabl\ne but grows slowly; growth is further impaired by addition o\nf diepoxybutane or mitomycin C to medium. Null mutant also e\nxhibits decreased abundance of mitochondrial proteins.\n mMDM30:Unknown ,, Unknown\n mYDR031W:Unknown ,, Unknown\n Cond711:t2+Vec\n mSCO2:Originally identified as a multicopy suppressor of a respira\ntory defective mutant; homolog of Sco1p,,\n mYLR077W:Unknown ,, Unknown\n mYPR117W:Unknown ,, Unknown\n mPET117:Required for assembly of active cytochrome c oxidase,,petite\n; unable to grow on non-fermentable carbon sources\n mPEX15:44 kDa phosphorylated integral peroxisomal membrane protein,\n44 kDa phosphorylated integral peroxisomal membrane protein,\nNull mutant lacks morphologically recognizable peroxisomes a\nnd shows cytosolic mislocalization of peroxisomal matrix pro\nteins; overexpression of Pex15p results in proliferation of \nER membranes\n mYKL027W:Unknown ,, Unknown\n Cond719:t4-SSD1\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n Cond724:t4+SSD1,H44\n mYAL027W:Unknown ,, Unknown\n Cond713:t4+Vec\n mYDR003W:Unknown ,, Unknown\n mHEM4:catalyzes the fourth step in the heme biosynthesis pathway,u\nroporphyrinogen III synthase,respiratory deficiency, accumul\nation of porphyrins, and heme auxotrophy\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCAP1:capping - addition of actin subunits,capping protein,Null mu\ntant is viable; severe deficit of actin cables and increased\n number of actin spots in the mother; round, relatively larg\ne cells\n mYLR252W:Unknown ,, Unknown\n mROM1:Gdp-GTP Exchange Protein (GEP) for the Rho1p Small GTP-bindi\nng Protein,,Synthetically lethal with ROM2 (growth arrest wi\nth small bud and cell lysis)\n mMRPL40:Mitochondrial ribosomal protein MRPL40 (YmL40),ribosomal pro\ntein (YmL40),\n Cond718:t4+SSD1wt\n mYUH1:ubiquitin hydrolase,ubiquitin hydrolase,\n mSIF2:Sir4p-Interacting Factor,,Null mutant is viable, exhibits in\ncreased telomeric silencing\n mMRPL49:mitochondrial ribosomal protein of the large subunit,ribosom\nal protein large subunit,\n mYEL041W:Unknown ,, Unknown\n mMSW1:mitochondrial tryptophanyl-tRNA synthetase,tryptophan-tRNA l\nigase,Null mutant is viable, respiratory deficient, defectiv\ne in mitochondrial protein synthesis\n Cond709:t0+Vec\n mYDR316W:Unknown ,, Unknown\n mCSM1:Hypothetical ORF,,missegregates chromosomes in meiosis\n mPET123:May be component of mitochondrial translation appartus and m\nay interact with small subunit of mitochondrial ribosomes or\n with Pet122p to promote translational initiation of cytochr\nome c oxidase subunit III mRNA,mitochondrial ribosomal prote\nin of small subunit,Null mutant is viable but is rho- (with \nlarge deletions in mtDNA); pet123 mutations can suppress pet\n122 mutations; some pet123 alleles show synthetic phenotypes\n with mrp1 mutations\n mYMR003W:Unknown ,, Unknown\n mRET3:vesicle coat component,vesicle coat component,ret3-1 mutant \nis thermosensitive and shows defects in retrieval of dilysin\ne-tagged proteins from the Golgi back to the ER\n mFKS3:Protein with similarity to Gls1p and Gls2p (GB:Z49212),,\n mCOX11:Mitochondrial membrane protein required for insertion of Cu(\nB) and magnesium during assembly of cytochrome c oxidase,,de\nficient in cytochrome oxidase\n mSEC4:Involved in transport and fusion of post-Golgi secretory ves\nicles to the plasma membrane,ras homolog , small GTP binding\n protein,null is inviable; conditional mutants show defects \nin secretion and accumulation of post-Golgi vesicles under n\non-permissive conditions\n Cond717:t2-SSD1\n mYGR042W:Unknown ,, Unknown\n mYOR291W:Unknown ,, Unknown\n mUGA2:involved in utilization of GABA as a nitrogen source,succina\nte semialdehyde dehydrogenase,Null mutant is viable but cann\not grow with GABA as the only nitrogen source.\n Cond149:sap30\n Cond725:t4-SSD1,M31\n mABC1:multicopy suppressor of a cytochrome b mRNA translation defe\nct, essential for the electron transfer in the bc1 complex,,\nnull mutant is viable, no oxygen uptake and no growth on non\n-fermentable media\n Cond708:t0+SSD1\n mYLL047W:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYGL047W:Unknown ,, Unknown\n mSEN34:tRNA splicing endonuclease 34kDa subunit; homologous to the \n42-kDa subunit, SEN2; contains active site for 3' splice sit\ne cleavage,tetrameric tRNA splicing endonuclease 34 kDa subu\nnit,Null mutant is inviable and shows H242A impaired 3'splic\ne site cleavage\n mRHC18:Protein involved in recombination repair, homologous to S. p\nombe rad18,,Null mutant is inviable\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond712:t4+SSD1\n Cond723:t2-SSD1,M31\n mYEL028W:Unknown ,, Unknown\n mYMR040W:Unknown ,, Unknown\n mYML005W:Unknown ,, Unknown\n Cond714:t0+SSD1wt\n Cond715:t0-SSD1\n mCOG5:Unknown ,, Unknown\n mIMP2:Inner membrane protease (mitochondrial protein),protease,\n mDJP1:DnaJ-like protein required for Peroxisome biogenesis; Djp1p \nis located in the cytosol,,Null mutant is viable but shows p\nartial mislocalisation of peroxisomal matrix proteins to the\n cytosol\n mPCL10:PHO85 cyclin,,Null mutant is viable.\n mYMR160W:Unknown ,, Unknown\n mATP10:essential for assembly of a functional mitochondrial ATPase \ncomplex,,loss of rutamycin sensitivity in mitochondrial ATPa\nse but no effect on respiratory enzymes\n Cond710:t2+SSD1\n mYBR178W:Unknown ,, Unknown\n mYJL152W:Unknown ,, Unknown\n mMDM30 mIMP2
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity