Module number 839




Database revision : gnsdb28.10
Date : Tue Feb 25 17:07:49 2003
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mYER130C:Unknown ,, Unknown\n mYNL319W:Unknown ,, Unknown\n mYIL015C-A:Unknown ,, Unknown\n mHAA1:Homolog of Ace1 Activator,,\n mYOL163W:Unknown ,, Unknown\n mYKL044W:Unknown ,, Unknown\n mTOS3:Hypothetical ORF,,\n mYLR124W:Unknown ,, Unknown\n mTYE7:may be involved in glycolytic gene expression,33 kDa , serin\ne-rich protein, is a potential member of the bHLH/leucine-zi\npper protein family,Null mutant is viable; expression of eno\nlase genes is reduced three-fivefold in null mutant; gcr1 ty\ne7 double deletion mutants exhibit additive defects in enola\nse expression. TYE7 was isolated as a dominant suppressor of\n gcr1 mutations\n mMSN4:multicopy suppressor of snf1 mutation,zinc finger protein,Nu\nll mutant is viable; msn2 msn4 double deletion mutants exhib\nit higher sensitivity to different stresses, including carbo\nn source starvation, heat shock and severe osmotic and oxida\ntive stresses\n mYHR125W:Unknown ,, Unknown\n mUBP11:Ubiquitin-specific protease,ubiquitin-specific protease,viab\nle\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n mTIR4:Hypothetical ORF,cell wall mannoprotein,inviable under anaer\nobic conditions\n mBEM3:Gtpase-activating protein activity toward the essential bud-\nsite assembly GTPase Cdc42,rho GTPase activating protein (GA\nP),Null mutant is viable.\n mADR1:Positive transcriptional regulator of ADH2 and peroxisomal p\nrotein genes,positive transcriptional regulator,abolished de\nrepression of ADH2\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n mYJL084C:Unknown ,, Unknown\n mRGM1:Putative transcriptional repressor with proline-rich zinc fi\nngers,transcriptional repressor with proline-rich zinc finge\nrs (putative),Null mutant is viable; overexpression of RGM1 \ngreatly impairs cell growth.\n mYFR022W:Unknown ,, Unknown\n mFIT1:Facilitator of Iron Transport,Cell wall protein involved in \niron uptake,Impaired siderophore-iron uptake, activation of \nthe major iron-dependent transcription factor AFT1.\n mFRE5:similar to FRE2,,\n mFUS1:cell-surface protein required for cell fusion,,Null mutant i\ns viable; in fus1 x fus1 matings there is an interruption of\n the mating process just before cytoplasmic fusion\n mPGU1:Endo-polygalacturonase,endo-polygalacturonase,Null mutant is\n viable; exhibits clear halo around colonies on polygalactur\nonate medium\n mYFL013W-A:Unknown ,, Unknown\n mABM1:aberrant microtubules,,\n mHKR1:cell surface protein that may regulate cell wall beta-glucan\n synthesis and bud site selection; Hanenula mrakii killer to\nxin-resistance protein,contains EF hand motif , type I trans\nmembrane protein,Null mutant is inviable; overexpression con\nfers resistance to Hanenula mrakii killer toxin\n mAST1:Protein involved in targeting of plasma membrane [H+]ATPase,\n,multicopy AST1 suppresses pma1 alleles defective for target\ning\n mJIP3:Unknown ,, Unknown\n mYDR250C:Unknown ,, Unknown\n mYAR030C:Unknown ,, Unknown\n mYIL055C:Unknown ,, Unknown\n mKSS1:Recovery from alpha factor arrest,MAP kinase , involved in p\nheromone signal transduction,\n mYER135C:Unknown ,, Unknown\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n mDAN1:Delayed Anaerobic,cell wall mannoprotein , induced during an\naerobic growth,Null mutant is viable\n mLSB3:LAs17 Binding protein,,\n mTHI12:thiamine regulated gene, homologous to nmt1a in Schizosaccha\nromyces pombe; putatively involved in pyrimidine biosynthesi\ns,,\n mYGL046W:Unknown ,, Unknown\n mYDR149C:Unknown ,, Unknown\n mYHR097C:Unknown ,, Unknown\n mRNP1:ribonucleoprotein 1,RNA binding protein (putative),Null muta\nnt is viable\n mVID24:also involved in vacuolar protein targeting,peripheral vesic\nle membrane protein,Null mutant is viable, defective in fruc\ntose-1,6-bisphosphatase dergadation\n mYGL039W:Unknown ,, Unknown\n mSUT1:Involved in sterol uptake,,Null mutant is viable\n mPAI3:Cytoplasmic inhibitor of proteinase Pep4p,inhibitor of prote\ninase Pep4p,Null mutant is viable but shows increased rate o\nf protein degradation\n mCNA1:calmodulin binding protein homologous to mammalian calcineur\nin,calcineurin subunit A,Null mutant is viable (no obvious p\nhenotype)\n mYDR374C:Unknown ,, Unknown\n mRDS1:Unknown ,, Unknown\n mYLR445W:Unknown ,, Unknown\n mYKR041W:Unknown ,, Unknown\n mWSC2:cell wall integrity and stress response component 2,contains\n novel cysteine motif , integral membrane protein (putative)\n , similar to SLG1 (WSC1), WSC3 and WSC4,Null mutant is viab\nle and shows no phenotypes; slg1 (wsc1)-null wsc2-null doubl\ne mutant shows a lysis defect on YPD at room temperature and\n heat shock sensitivity; overexpression of WSC genes suppres\nses heat shock sensitivity of hyperactivated ras mutant; hea\nt shock sensitivity of wsc mutant strain is suppressed by de\nletion of ras2\n mCLG1:cyclin-like protein that interacts with Pho85p in affinity c\nhromatography,,Null mutant is viable\n mRHO2:Gtp-binding protein of the rho subfamily of ras-like protein\ns,GTP-binding protein , rho subfamily,null is viable\n mYBR285W:Unknown ,, Unknown\n mGCN4:transcriptional activator of amino acid biosynthetic genes,t\nranscriptional activator of amino acid biosynthetic genes,Th\ne null mutant is viable but requires arginine on minimal med\nium and issensitive to 3-amino-1,2,4-triazole. General contr\nol of amino acid synthesis non-derepressible in the null mut\nant.\n Cond65:fus3(haploid)\n mGAT2:Product of gene unknown,,\n mPMP2:May regulate plasma membrane H(+)-ATPase; nearly identical t\no PMP1,proteolipid associated with plasma membrane H(+)-ATPa\nse (Pma1p),Null mutant is viable; pmp1 pmp2 double mutant di\nsplays lower Vmax for the plasma membrane H(+)-ATPase (Pma1p\n)\n mSTP3:Involved in pre-tRNA splicing and in uptake of branched-chai\nn amino acids,,\n mSTP4:Involved in pre-tRNA splicing and in uptake of branched-chai\nn amino acids,,\n mCHS3:Required for chitin synthesis,chitin synthase 3,Null mutant \nis viable; reduced chitin levels; lack chitin synthase III a\nctivity in vitro; Derepressed INO1 transcription\n mLEU4:leucine biosynthesis,alpha-isopropylmalate synthase (2-isopr\nopylmalate synthase),Null mutant is viable, Leu+\n mGDS1:involved in nuclear control of mitochondria,,Null mutant is \nviable, shows partial impairment of growth on medium contain\ning glycerol as the carbon source. Overexpxression suppresse\ns NAM9-1 glycerol deficient phenotype\n mYMR102C:Unknown ,, Unknown\n mYPL166W:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSFH5:Unknown ,, Unknown\n mYCR022C:Unknown ,, Unknown\n mPRM5:pheromone-regulated membrane protein,,\n mMID2:Protein required for mating,,Null mutant is viable, dies whe\nn exposed to mating pheromone\n mYGR250C:Unknown ,, Unknown\n mDIG1:Down-regulator of Invasive Growth, Regulator of Sterile Twel\nve, binds Fus3 and Ste12,MAP kinase-associated protein,Null \nmutant is viable, shows abnormal bud morphology; dig1 dig2 d\nouble mutants show constitutive mating defect and invasive g\nrowth; overexpression causes pheromone resistance\n mYOL101C:Unknown ,, Unknown\n mSKT5:protoplast regeneration and killer toxin resistance gene, ma\ny be a post-translational regulator of chitin synthase III a\nctivity, interacts with Chs3p,,Null mutant is viable, resist\nant to Calcofluor white, exhibits a reduction in cell wall c\nhitin and chitin synthase III activity\n mCNB1:Type 2B protein phosphatase; regulatory B subunit of calcine\nurin,calcineurin regulatory B subunit , type 2B protein phos\nphatase , calcineurin regulatory B subunit , type 2B protein\n phosphatase,Null mutant is viable, Li+ and Na+ sensitive, c\nnb1 fks1 and cnb1 vma3 double mutants are inviable\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYJL195C:Unknown ,, Unknown\n mTPO2:Unknown ,, Unknown\n mTPO3:Unknown ,, Unknown\n mYNL190W:Unknown ,, Unknown\n mYOR325W:Unknown ,, Unknown\n mYOL162W:Unknown ,, Unknown\n mMEP3:ammonia permease of high capacity and low affinity; shows se\nquence similarity to Mep1p and Mep2p,NH4+ transporter,Null m\nutant is viable. mep1 mep2 mep3 triple mutants cannot grow o\nn media containing less than 5mM NH4+ as the sole nitrogen s\nource\n mSPO19:sporulation-defective; SPO19 was found as a weak high-copy s\nuppressor of the spo1-1 ts mutation. The gene is specificall\ny induced late in meiosis (Primig et al. (2000) Nat Genet 26\n:415-423),meiosis-specific GPI-protein,Null mutant is viable\n; unable to form spores\n mYHL012W:Unknown ,, Unknown\n mYPL033C:Unknown ,, Unknown\n mYER066C-A:Unknown ,, Unknown\n mTEF2:translational elongation factor EF-1 alpha,translational elo\nngation factor EF-1 alpha,Null mutant is viable, tef1 tef2 d\nouble deletion mutants are inviable\n mYLR040C:Unknown ,, Unknown\n mHRK1:Unknown ,, Unknown\n mYOL047C:Unknown ,, Unknown\n Cond538:fus3D/wtlog10(intensity)\n mYGR243W:Unknown ,, Unknown\n mMSB1:Protein that may play a role in polarity establishment and b\nud formation,,multicopy suppressor of cdc24 and cdc42 ts mut\nations\n mMSB2:putative integral membrane protein,integral membrane protein\n (putative),multicopy suppressor of cdc24 ts mutation\n mYDR539W:Unknown ,, Unknown\n mHXT10:high-affinity hexose transporter,high affinity hexose transp\norter,\n mYDR249C:Unknown ,, Unknown\n mYOR296W:Unknown ,, Unknown\n mYGL262W:Unknown ,, Unknown\n mARN2:Siderophore transporter for triacetylfusarinine C,triacetylf\nusarinine C transporter,YHL047c disrupted cells are unable t\no take up and utilize iron from triacetylfusarinine C und fu\nsigen\n mYCR099C:Unknown ,, Unknown\n mYGR290W:Unknown ,, Unknown\n mYGR069W:Unknown ,, Unknown\n mGSC2:Highly similar to FKS1 (GSC1). GSC2 and FKS1 encode redundan\nt catalytic components of 1,3-beta-glucan synthase. Deletion\n of both is lethal,1,3-beta-D-glucan synthase catalytic comp\nonent,Null mutant is viable and shows partially reduced 1,3-\nbeta-glucan synthase activity\n mYKR032W:Unknown ,, Unknown\n mHXT17:Hexose transporter,hexose transporter,\n mSRL3:Suppressor of rad53 lethality,,\n mYIR042C:Unknown ,, Unknown\n mYLR415C:Unknown ,, Unknown\n mYDR220C:Unknown ,, Unknown\n mRGA2:contains a Rho-GAP domain and two LIM domains, similar to Rg\na1p and all known Rho-GAPs,Rho-GTPase Activating Protein,Nul\nl mutants are viable but increase the restrictive temperatur\ne of a cdc24-4 strain and increase the constitutive activati\non of the pheromone response pathway in conjungtion with mut\nations in RGA1 and BEM3; overexpression of RGA2 causes a dec\nrease in the restrictive temperature of a cdc42-1 strain\n mYIR035C:Unknown ,, Unknown\n mSKT5 mCHS3 mKSS1 mDIG1 mBEM3 mYIL055C mCNB1 mCNA1
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity