Module number 837




Database revision : gnsdb28.10
Date : Tue Feb 25 17:07:44 2003
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mKRE23:Killer toxin REsistant,,Null mutant is K1 killer toxin resis\ntent\n mYLR124W:Unknown ,, Unknown\n mRTA1:involved in 7-aminocholesterol resistance,,Null mutant is vi\nable; overexpression confers resistance to 7-aminocholestero\nl\n mDCG1:Product of gene unknown,,\n mYGL132W:Unknown ,, Unknown\n mYOL037C:Unknown ,, Unknown\n mYOR366W:Unknown ,, Unknown\n mFYV2:Function required for Yeast Viability on toxin exposure,,K1 \nkiller toxin hypersensitivity\n mYHR125W:Unknown ,, Unknown\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mDIT1:Disp. for spores & spore viability - required for dityrosine\n accumul. in the outer spore wall (s.w.), s.w. maturation & \nresist. to ether & lytic enzymes. Spore-autonomous function \nin heterozygotes. mRNA is trans. mid/late in s.w. formation,\nfirst enzyme in dityrosine synthesis in the outer layer of t\nhe spore wall pathway, converting L-tyrosine to N-formyl-L-t\nyrosine,lack outermost layer of spore wall\n mYDL032W:Unknown ,, Unknown\n mYOL015W:Unknown ,, Unknown\n mYJL182C:Unknown ,, Unknown\n mUBP16:putative deubiquitinating enzyme,deubiquitinating enzyme (pu\ntative),\n mMPH3:Unknown ,, Unknown\n mYOR029W:Unknown ,, Unknown\n mYJL135W:Unknown ,, Unknown\n mYCR064C:Unknown ,, Unknown\n mYPL216W:Unknown ,, Unknown\n mYDR250C:Unknown ,, Unknown\n Cond:\n mYLR125W:Unknown ,, Unknown\n mYBL010C:Unknown ,, Unknown\n Cond916:(99i5)__HBY4_YPGL+G_NormInt\n mSPH1:SPa2-Homolog; protein involved in shmoo formation and requir\ned for bipolar bud site selection (GB:AF008236).,Spa2p homol\nog,Null mutant is viable but results in defects in shmoo for\nmation.\n mYDR112W:Unknown ,, Unknown\n mYNL033W:Unknown ,, Unknown\n mYMR144W:Unknown ,, Unknown\n mYPL162C:Unknown ,, Unknown\n Cond268:yor009w\n mMDJ2:Protein of the mitochondrial inner membrane with similarity \nto E. coli DnaJ and other DnaJ-like proteins, function parti\nally overlaps that of Mdj1p,chaperonin,Null mutant is viable\n, mdj1 mdj2 double mutants display severe grwoth defects at \nhigh temperature\n Cond900:(11i1)_S150-2B_YPGL_NormInt\n mMSS2:cox1 pre-mRNA splicing factor,cox2 pre-mRNA splicing factor,\nSuppression of a mitochondrial RNA splice defect; COX1 pre-m\nRNA processing factor\n mYDR102C:Unknown ,, Unknown\n mYFR012W:Unknown ,, Unknown\n mGAL4:Positive regulator of GAL genes,zinc finger transcription fa\nctor of the Zn(2)-Cys(6) binuclear cluster domain type,Null \nmutant is viable, cannot utilize galactose as sole carbon so\nurce\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mYPL191C:Unknown ,, Unknown\n Cond59:erp4\n mCAT8:Zinc-cluster protein involved in activating gluconeogenic ge\nnes; related to Gal4p,zinc-cluster protein involved in activ\nating gluconeogenic genes; related to Gal4p,Null mutant is v\niable but unable to grow on non-fermentable carbon sources d\nue to failure to derepress all major gluconeogenic enzymes; \noverexpression of Cat8p suppress inability of snf1 and snf4 \nmutants to grow on ethanol\n mYOR055W:Unknown ,, Unknown\n mTEP1:Similar to human tumor suppressor gene known as TEP1, MMAC1 \nand PTEN1,tyrosine phosphatase (putative),\n mYDR065W:Unknown ,, Unknown\n mYGL138C:Unknown ,, Unknown\n mICY2:Interacting with the cytoskeleton,,\n mYNR062C:Unknown ,, Unknown\n mYMR031W-A:Unknown ,, Unknown\n mREC104:meiosis-specific recombination gene, dispensable for mitotic\n recombination and axial elements in meiosis, required for t\nripartite synaptonemal complexes, meiotic recombination and \nspore viability; classified as an early recombination gene,m\neiosis-specific protein,Null mutant is viable, rec104 mutant\ns exhibit reduced meiotic DNA recombination, executes meiosi\ns I early; rec104 is rescued by spo13 and is epistatic to ra\nd52 spo13\n Cond871:yhe710-ss\n mDNA43:Protein required for S-phase (DNA synthesis) initiation or c\nompletion,,Null mutant is inviable; conditional allele demon\nstrates cell-cycle arrest at the restrictive temperature wit\nh a large-budded terminal phenotype\n mYDR290W:Unknown ,, Unknown\n mGAT4:very short and so far mRNA can't be detected,very short and \nso far mRNA can't be detected,being investigated\n mYOR364W:Unknown ,, Unknown\n mYGR126W:Unknown ,, Unknown\n mYJR038C:Unknown ,, Unknown\n mYOR343C:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCIT3:Mitochondrial isoform of citrate synthase,citrate synthase,N\null mutant shows severely reduced growth on the respiratory \nsubstrate glycerol in a delta cit1 background\n mHPA2:Histone and other Protein Acetyltransferase; Has sequence ho\nmology to known HATs and NATs,histone acetyltransferase,Null\n mutant is viable and does not show any detectable phenotype\n mPOR2:Mitochondrial porin,voltage dependent anion channel (YVDAC2)\n,Null mutant is viable; omp2 por2 double null mutant shows p\noor growth; POR2 is a multicopy suppressor of omp2 null temp\nerature-sensitive petite phenotype\n mYCR022C:Unknown ,, Unknown\n mYHL005C:Unknown ,, Unknown\n mYFL054C:Unknown ,, Unknown\n mYBL065W:Unknown ,, Unknown\n mYDL034W:Unknown ,, Unknown\n mYBR232C:Unknown ,, Unknown\n mYDL187C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mBFA1:Byr four alike,,Null mutant is viable; mutants are sensitive\n to microtubule inhibitors, exhibit defects in mitotic check\npoints, and exhibit moderate defects in mating efficiency\n mYML084W:Unknown ,, Unknown\n mYOR314W:Unknown ,, Unknown\n mYGL146C:Unknown ,, Unknown\n mSPO13:Spo13 acts as a transcriptional activator in a one-hybrid as\nsay (see Henninger et al (1996) SPO13 and control of meiotic\n chromosome segregation in Saccharomyces cerevisiae),,Null m\nutant is viable, defective for sporulation; loss of function\n results in a single division during meiosis (with some chro\nmosomes segregating reductionally or aberrantly depending on\n strain background), occurring slightly earlier or at the ti\nme of wild type meiosis I, and dyad asci containing two dipl\noid spores. spo13 rescues the meiotic lethality of early Rec\n- mutants and Rec+ haploids. Gain of function causes a CDC28\n-dependent arrest at M-phase in mitosis and a delay in MI nu\ncleardivision.\n mYMR324C:Unknown ,, Unknown\n mYOR325W:Unknown ,, Unknown\n mYLL059C:Unknown ,, Unknown\n mYPR014C:Unknown ,, Unknown\n mZIP2:Required for 'ZIPpering' up meiotic chromosomes during chrom\nosome synapsis,,Null mutant is viable but is defective in ch\nromosome synapsis, but not chromosome pairing, and causes me\niosis I non-disjunction and reduced homologous recombination\n mYDR314C:Unknown ,, Unknown\n Cond154:sgt2\n mYPT11:similar to Ypt1 and other Ras-like GTP-binding proteins,,\n mYVC1:Unknown ,, Unknown\n mLYS14:Transcriptional activator of lysine pathway genes with 2-ami\nnoadipate semialdehyde as co-inducer; saccharopine reductase\n synthesis,,Lysine requiring\n mHOP1:Meiosis-specific protein involved in homologous chromosome s\nynapsis and chiasmata formation,DNA binding protein,decrease\nd levels of meiotic crossing over and intragenic recombinati\non between markers on homologous chromosomes\n mYIL006W:Unknown ,, Unknown\n mYGR051C:Unknown ,, Unknown\n mYOR376W:Unknown ,, Unknown\n mYBL073W:Unknown ,, Unknown\n mDUR3:Urea active transport protein,,Null mutant is viable; urea d\negradation deficient\n mYDR401W:Unknown ,, Unknown\n mYAR047C:Unknown ,, Unknown\n mSAE2:Involved in meiotic recombination and chromosome metabolism,\n,Null mutant is viable, weakly sensitive to methyl methane s\nulfonate, shows blocked turnover of meiosis-specific double-\nstrand breaks, similar to rad50S mutant\n mNKP2:Unknown ,, Unknown\n mYGL118C:Unknown ,, Unknown\n mESC8:Unknown ,, Unknown\n mYOR268C:Unknown ,, Unknown\n mYIR042C:Unknown ,, Unknown\n mYLR415C:Unknown ,, Unknown\n mYDL242W:Unknown ,, Unknown\n mRAD24:checkpoint protein,cell cycle exonuclease (putative),radiati\non sensitive\n mYIL025C:Unknown ,, Unknown\n mYGR066C:Unknown ,, Unknown\n mYCR001W:Unknown ,, Unknown\n mYOR050C:Unknown ,, Unknown\n

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Computational Genomics Lab, Tel-Aviv uniresity