Module number 824




Database revision : gnsdb28.10
Date : Tue Feb 25 17:05:36 2003
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mYJL211C:Unknown ,, Unknown\n mYBR280C:Unknown ,, Unknown\n mCPT1:Phospholipid biosynthesis,sn-1,2-diacylglycerol cholinephosp\nhotransferase,Null mutant is viable, cpt1 ept1 double deleti\non mutants are viable\n mYBR077C:Unknown ,, Unknown\n mVPS74:Unknown ,, Unknown\n mGYP1:Gtpase activating protein for Ypt1p,GTPase activating protei\nn (GAP),Null mutant is viable and shows no phenotype\n mSNX4:Sorting NeXin,,\n mPPM1:carboxy methyl transferase for protein phosphatase 2A cataly\ntic subunit,carboxy methyl transferase for protein phosphata\nse 2A catalytic subunit,Mutant is rapamycin resistant, benom\nyl supersensitive, and nocodazole sensitive.\n mBRE5:Product of gene unknown,,null mutant is sensitive to brefeld\nin A\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mORM2:Unknown ,, Unknown\n mDOM34:an ORF of unknown function located in a centromeric region d\nuplicated between chromosomes III and XIV (DOM34 homologue o\nn chromosome III is a pseudogene),,\n mURA4:Third step in pyrimidine biosynthesis pathway,dihydrooratase\n,Null mutant is viable and requires uracil\n mINP54:INositol polyphosphate 5-Phosphatase, fourth one identified;\n has homology to Type I mammalian inositol polyphosphate 5-p\nhosphatases,inositol polyphosphate 5-phosphatase,\n mFET3:FET3 encodes a ferro-O2-oxidoreductase that is part of the h\nigh-affinity iron transport system,multicopper oxidase,The n\null mutant is viable but defective for high affinity Fe(II) \nuptake. The null mutant is inviable when environmental iron \nis limiting.\n mYBL006C:Unknown ,, Unknown\n mYJR097W:Unknown ,, Unknown\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n mHNT1:Hint homolog, member of the histidine triad superfamily of n\nucleotide-binding proteins,,\n mYJR083C:Unknown ,, Unknown\n mSTV1:Stv1p and Vph1p may be equivalent subunits for vacuolar-type\n H(+)-ATPases located on different organelles,110 kDa subuni\nt; not in vacuole membrane , vacuolar H-ATPase,Null mutant i\ns viable, displays additive phenotypes in combination with v\nph1 null mutations\n mYJL084C:Unknown ,, Unknown\n mSTE50:involved in pheromone signal transduction pathway; interacts\n with G protein and Ste11p,contains SAM (sterile alpha motif\n),Null mutant is viable, sterile, has a modulated sensitivit\ny to alpha-pheromone\n mPTM1:Putative membrane protein,membrane protein (putative),Null m\nutant is viable, no observable phenotype\n mYBR255W:Unknown ,, Unknown\n mPRD1:Saccharolysin (oligopeptidase yscD),,Null mutant is viable b\nut exhibits a decrease in the intracellular degradation of p\neptides\n mYOR131C:Unknown ,, Unknown\n mYDL222C:Unknown ,, Unknown\n mMCM22:Required for maintenance of chromosomes and minichromosomes,\n,Null mutant is viable\n mYBL010C:Unknown ,, Unknown\n mYJR149W:Unknown ,, Unknown\n mYEL059W:Unknown ,, Unknown\n mSEY1:Unknown ,, Unknown\n mFPS1:Suppressor of tps1/fdp1 and member of the MIP family of tran\nsmembrane channels; may be involved in glycerol efflux,glyce\nrol channel protein,Null mutant is viable\n mARL1:Hydrolyzes GTP; myristylated; in soluble fraction,ADP-ribosy\nlation factor-like protein 1,Null mutant is viable\n mYBL046W:Unknown ,, Unknown\n Cond937:t=0\n mHMX1:Unknown ,, Unknown\n mYDL110C:Unknown ,, Unknown\n mSAP190:190 kDa protein that associates with the SIT4 phosphatase in\n a cell cycle dependent manner,type 2A-related protein phosp\nhatase,Null mutant is viable\n mTAT1:Amino acid transport protein for valine, leucine, isoleucine\n, and tyrosine,amino acid transport protein for valine, leuc\nine, isoleucine, and tyrosine,\n mSSK1:Two-component signal transducer that with Sln1p regulates os\nmosensing MAP kinase cascade(suppressor of sensor kinase),tw\no-component signal transducer that with Sln1p regulates osmo\nsensing MAP kinase cascade(suppressor of sensor kinase),Null\n mutant is viable; suppresses the lethality of sln1 or ypd1 \ndisruption mutants\n mNIT2:Nit protein, nitrilase superfamily member,,\n mCYC1:iso-1-cytochrome c,iso-1-cytochrome c,Cytochrome c deficienc\ny\n mOPI1:Negative regulator of phospholipid biosynthesis,,The null mu\ntant is viable but constitutively accumulates INO1 mRNA.\n mYPL184C:Unknown ,, Unknown\n mOPI3:Second and third steps of methylation pathway for phosphatid\nylcholine biosynthesis,methylene-fatty-acyl-phospholipid syn\nthase (unsaturated phospholipid N-methyltransferase),Null mu\ntant is viable, temperature sensitive in the presence of mon\nomethylethanolamine, exhibits an inositol secretion phenotyp\ne\n mSLX1:Hypothetical ORF,,\n mMLF3:Protein of unknown function,,Null mutant is viable and hyper\nsensitive to leflunomide\n mYCR079W:Unknown ,, Unknown\n mKSP1:Serine/threonine kinase similar to casein kinase II and othe\nr serine/threonine protein kinases,,Null mutant is viable\n mLYS7:Involved in lysine biosynthesis, oxidative stress protection\n,copper chaperone for superoxide dismutase Sod1p,Null mutant\n is viable, methionine and lysine auxotroph, pH and temperat\nure sensitive; sensitive to superoxide generating drugs and \nlight irradiation, exhibits diminution of calcineurin activi\nty\n mBSD2:metal homeostasis protein; putative membrane protein,,Null m\nutant is viable; suppressor of oxygen toxicity in sod1 mutan\nts, increased sensitivity to copper and cadmium toxicity, el\nevation in copper ion accumulation\n mYCR076C:Unknown ,, Unknown\n mYKL050C:Unknown ,, Unknown\n mSTP4:Involved in pre-tRNA splicing and in uptake of branched-chai\nn amino acids,,\n Cond17:bub1(haploid**2,10)\n mYBR108W:Unknown ,, Unknown\n mYML117W-A:Unknown ,, Unknown\n mMRPL13:mitochondrial ribosomal protein YmL13,ribosomal protein (YmL\n13),Null mutant is viable, grows poorly on non-fermentable c\narbon sources\n mCHS6:Involved in chitin biosynthesis and/or its regulation,,Reduc\ned levels of chitin, temperature-sensitive growth on rich me\ndium in certain genetic backgrounds\n mYBR071W:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYML117W:Unknown ,, Unknown\n mTIS11:Zinc finger containing homolog of mammalian TIS11, glucose r\nepressible gene,,Null mutant is viable but alters metabolism\n that is reflected by a pH change on YPD plates.\n mYBR235W:Unknown ,, Unknown\n mAOR1:actin overexpression resistant,,Sensitive to NaCl and NaF at\n >35 deg. C.\n mBOP2:bypass of PAM1,,\n mRPL15B:Homology to rat L15,ribosomal protein L15B (YL10) (L13B) (rp\n15R),\n mYOL003C:Unknown ,, Unknown\n mGPG1:Unknown ,, Unknown\n mVTC1:Null mutant identified in different genetic screens both by \nits ability to reverse the Cdc42p suppression of a cdc24-4ts\n mutant and its ability to suppress the vacuolar ATPase null\n phenotype,S. pombe Nrf1p homolog (97% identical in predicte\nd amino acid sequence),Null mutant is viable, but exhibits b\noth reduced V-ATPase in the vacuolar membrane and reduced H(\n+)-ATPase(Pma1p) in the plasma membrane\n mVAM7:Regulator of vacuolar morphogenesis,heptad repeat motif , hy\ndrophilic protein,Null mutant is viable, exhibits prominent \nlarge vacuoles\n mAPS2:Related to the sigma subunit of the mammalian plasma membran\ne clathrin-associated protein (AP-2) complex,clathrin associ\nated protein complex small subunit,null mutant is viable; sl\night effect on chc1-ts cell growth\n mSWD3:YBR175W,,\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYNL122C:Unknown ,, Unknown\n mAPS3:sigma3-like subunit of the yeast AP-3 complex which function\ns in transport of alkaline phosphatase to the vacuole via th\ne alternate pathway, suppressor of loss of casein kinase 1 f\nunction,,Null mutant is viable, rescues yck1,yck2 double mut\nant\n mSDC1:YDR469W,,\n mYMR073C:Unknown ,, Unknown\n mSED1:putative cell surface glycoprotein,cell surface glycoprotein\n (putative),Null mutant is viable; during stationary phase, \nnull mutants exhibit increased sensitivity to Zymolyase.\n mEAF6:Unknown ,, Unknown\n mYMR157C:Unknown ,, Unknown\n mGDA1:converts nucleoside diphosphates to nucleoside monophosphate\ns to recycle nucleosides and promote transport of additional\n nucleotide sugars into golgi,guanosine diphosphatase of Gol\ngi membrane,Null mutant is viable and has partial block in m\nannosylation of proteins and sphingolipids\n mYDL162C:Unknown ,, Unknown\n mBAP2:contains 12 predicted transmembrane domains,amino acid perme\nase for leucine, valine, and isoleucine (putative),reduced u\nptake of leucine, isoleucine, and valine\n mYJR119C:Unknown ,, Unknown\n mAPL3:clathrin Associated Protein complex Large subunit,clathrin a\nssociated protein complex large subunit,Null mutant is viabl\ne\n mYGL226W:Unknown ,, Unknown\n mYMR099C:Unknown ,, Unknown\n mYBL107C:Unknown ,, Unknown\n mYBR062C:Unknown ,, Unknown\n mPPH21:serine-threonine protein phosphatase 2A,,Null mutant is viab\nle, pph21 pph22 mutants produce very small spores in some st\nrain backgrounds and are inviable in others, pph21 pph22 pph\n3 mutants are inviable\n mRCE1:Protease involved in ras and a-factor terminal proteolysis,p\nrotease,Null mutant is viable, has defects in Ras localizati\non and signaling, and suppresses the activated phenotype of \nthe RAS2val19 allele\n mMUD1:U1 snRNP A protein,U1 snRNP A protein,Null mutant is viable\n mHXT17:Hexose transporter,hexose transporter,\n mTRS33:Trapp subunit of 33 kDa,,Null mutant is viable\n mSGN1:contains one RNA recognition (RRM) domain,,\n mHAL5:Protein kinase homolog, mutant is salt and pH sensitive,,\n mRGA2:contains a Rho-GAP domain and two LIM domains, similar to Rg\na1p and all known Rho-GAPs,Rho-GTPase Activating Protein,Nul\nl mutants are viable but increase the restrictive temperatur\ne of a cdc24-4 strain and increase the constitutive activati\non of the pheromone response pathway in conjungtion with mut\nations in RGA1 and BEM3; overexpression of RGA2 causes a dec\nrease in the restrictive temperature of a cdc42-1 strain\n

this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity