Module number 816




Database revision : gnsdb28.10
Date : Tue Feb 25 17:04:39 2003
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Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond796:Ca5'\n Cond399:Nitrogen_Depletion_8_h\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n mSET6:Hypothetical ORF,,\n Cond798:Ca30'\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response.  Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cond362:dtt_000_min__dtt-2\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond400:Nitrogen_Depletion_12_h\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond834:tlc1_Expt.2_Passage_6\n mSDP1:Unknown ,, Unknown\n Cond467:steady_state_21_dec_C_ct-2\n Cond416:YPD_10_h__ypd-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond810:Na45'\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n mYDL222C:Unknown ,, Unknown\n Cond445:Msn4_overexpression\n Cond822:tlc1_Expt.1_Passage_3\n Cond802:CaFK30'\n mYOL150C:Unknown ,, Unknown\n Cond300:Heat_Shock_05_minutes_hs-1\n mYGR052W:Unknown ,, Unknown\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYLR252W:Unknown ,, Unknown\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mHOR2:RHR2 (GPP1) encodes another DL-glycerol-3-phosphatase,DL-gly\ncerol-3-phosphatase,\n mYBR056W:Unknown ,, Unknown\n mYLR108C:Unknown ,, Unknown\n mYOL085C:Unknown ,, Unknown\n mYGR053C:Unknown ,, Unknown\n mHOR7:hyperosmolarity-responsive gene,,\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond452:sucrose_vs._reference_pool_car-1\n mSGA1:intracellular sporulation-specific glucoamylase involved in \nglycogen degradation. Induced during starvation of a/a late \nin sporulation, but dispensable for sporulation,glucoamylase\n,suppression of growth arrest of cdc25\n Cond306:Heat_Shock_60_minutes_hs-1\n mYMR181C:Unknown ,, Unknown\n Cond797:Ca15'\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae.  Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mCIT1:citrate synthase. Nuclear encoded mitochondrial protein.,cit\nrate synthase,Null mutant is viable; disruption of both CIT1\n and CIT2 result in glutamate auxotrophy and poor growth on \nrich medium containing lactate\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCIT3:Mitochondrial isoform of citrate synthase,citrate synthase,N\null mutant shows severely reduced growth on the respiratory \nsubstrate glycerol in a delta cit1 background\n Cond293:HU\n mYNL274C:Unknown ,, Unknown\n Cond378:1M_sorbitol_-_15_min\n mPDE1:3',5'-Cyclic-nucleotide phosphodiesterase, low affinity,3',5\n'-cyclic-nucleotide phosphodiesterase, low affinity,Null mut\nant is viable\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mYBR116C:Unknown ,, Unknown\n mPRB1:dispensable for haploidization and sporulation, but needed f\nor full protein degradation during sporulation, and proper s\npore morphology,vacuolar protease B,Null mutant is viable, p\nrotease B deficient, has smaller spores than wild-type embed\nded in a thick matrix\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n mYNL115C:Unknown ,, Unknown\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond833:tlc1_Expt.2_Passage_5\n mTOR1:Involved in cell cycle signaling and meiosis,phosphatidylino\nsitol kinase homolog,Null mutant is viable, grows slowly; ra\npamycin resistance, tor1 tor2 double mutant is inviable\n mMCR1:NADH-cytochrome b5 reductase,NADH-cytochrome b5 reductase,\n Cond374:1.5_mM_diamide_(50_min)\n Cond370:1.5_mM_diamide_(10_min)\n mNTH1:hydrolyzes trehalose; may be inolved in growth transition fr\nom glucose to glycerol; shows significant sequence similarit\ny to Nth2p,neutral trehalase,Null mutant is viable\n mYBR203W:Unknown ,, Unknown\n Cond809:Na30'\n mHSP78:Similar to E. coli ClpB protein; involved in folding of some\n mitochondrial proteins,heat shock protein 78,Null mutant is\n viable but in ssc1 mutant background gives rho- phenotype\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYER053C:Unknown ,, Unknown\n mYIL089W:Unknown ,, Unknown\n mYBR269C:Unknown ,, Unknown\n Cond366:dtt_120_min_dtt-2\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond813:Na+FK30'\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mPIN3:[PSI+] induction,,Other phenotypes: overexpression of PIN3 a\nllows for the induction of the [PSI+] prion in strains cured\n of [PIN+].\n mAGP3:General amino acid permease with broad substrate specificity\n,amino acid permease,Null mutant is viable; loss of growth o\nn some amino acids as nitrogen source (leu, thr) in a strain\n which has no Gap1p or Agp1p function\n Cond801:CaFK15'\n Cond390:aa_starv_0.5_h\n Cond464:37_deg_growth_ct-1\n Cond320:heat_shock_17_to_37,_20_minutes\n mYLL020C:Unknown ,, Unknown\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond301:Heat_Shock_10_minutes_hs-1\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYCL042W:Unknown ,, Unknown\n Cond363:dtt_015_min_dtt-2\n mLAP4:vacuolar aminopeptidase ysc1,vacuolar aminopeptidase ysc1,Le\nucine aminopeptidase deficient\n Cond800:CaFK5'\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n mYBL064C:Unknown ,, Unknown\n mDCS2:Unknown ,, Unknown\n Cond2:ade2(haploid)\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n Cond375:1.5_mM_diamide_(60_min)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n Cond323:heat_shock_29_to_37,_20_minutes\n mYDR250C:Unknown ,, Unknown\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n mCMK1:Calmodulin-dependent protein kinase,calmodulin-dependent pro\ntein kinase,Null mutant is viable\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n mTSA2:Unknown ,, Unknown\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mGSP2:maintenance of nuclear organization; homologous to mammalian\n Ran, a small nuclear GTPase of the ras superfamily,GTP-bind\ning protein , Gsp1p homolog,Null mutant is viable\n Cond322:heat_shock_25_to_37,_20_minutes\n mPAI3:Cytoplasmic inhibitor of proteinase Pep4p,inhibitor of prote\ninase Pep4p,Null mutant is viable but shows increased rate o\nf protein degradation\n Cond459:YP_sucrose_vs_reference_pool_car-2\n mYDL124W:Unknown ,, Unknown\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYPS1:Gpi-anchored aspartic protease (Yapsin 1),GPI-anchored aspar\ntic protease,Null mutant is viable, defective in expression \nof somatostatin-28; yps1 mkc7 double disruptants are tempera\nture sensitive; yps1 mkc7 kex2 mutants are profoundly temper\nature sensitive and are cold sensitive\n mYPS3:Gpi-anchored aspartic protease (Yapsin 3),GPI-anchored aspar\ntic protease,Null mutant is viable\n mYDL023C:Unknown ,, Unknown\n mYOR121C:Unknown ,, Unknown\n mBAG7:Structural homolog of SAC7,GTPase activating protein (GAP),N\null mutant is viable; overexpression suppresses sac7 null mu\ntation\n Cond758:Heat_0'_(A)\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Cond835:tlc1_Expt.2_Passage_7\n Cond456:YP_glucose_vs_reference_pool_car-2\n mLSC2:beta subunit of succinyl-CoA ligase (synthetase; ATP-forming\n), a mitochondrial enzyme of the TCA cycle,,Null mutant is v\niable but grows slowly on minimal glycerol or pyruvate; muta\nnt suppresses idh2 null mutants for growth on glycerol\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYGR043C:Unknown ,, Unknown\n Cond417:YPD_12_h_ypd-2\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mGRE3:Induced by osmotic stress; similar to xylose reductase from \nother fungi,,\n mYAK1:Serine-threonine protein kinase,,viable, confers growth to s\ntrains deleted for tpk1, tpk2, tpk3 (genes encoding the cata\nlytic subunit of the cAMP-dependent kinase)\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n Cond811:Na60'\n mYHR087W:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n mYJL144W:Unknown ,, Unknown\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mMEP1:ammonia permease,ammonia permease,\n Cond324:heat_shock_33_to_37,_20_minutes\n mYMR040W:Unknown ,, Unknown\n mTPS1:Probable regulator of glucose influx into the cell & into gl\nycolytic pathway, indirectly regulating glucose-induced sign\nalling (activation & inactivation) & initial step(s) of gluc\nose metabolism. Homologue of E. coli otsA protein,trehalose-\n6-phosphate synthase/phosphatase complex 56 kDa synthase sub\nunit,null is viable, but does not grow on glucose and/or fru\nctose,and shows lack of trehalose\n mPUT1:proline oxidase,proline oxidase,inability to use proline as \na nitrogen source\n Cond380:1M_sorbitol_-_45_min_\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYOL047C:Unknown ,, Unknown\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond453:YP_ethanol_vs_reference_pool_car-2\n mMRP8:mitochondrial ribosomal protein,ribosomal protein,\n mGPD1:glycerol-3-phosphate dehydrogenase,glycerol-3-phosphate dehy\ndrogenase,lethal under conditions of osmotic stress, unable \nto grow on glycerol\n mHXT5:Member of superfamily of monosaccharide transporters,hexose \ntransporter,Null mutant is viable\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n mSRL3:Suppressor of rad53 lethality,,\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mTSA2 mYAK1 mDCS2

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Computational Genomics Lab, Tel-Aviv uniresity