Module number 652




Database revision : gnsdb28.10
Date : Tue Feb 25 17:02:41 2003
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Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n mYNR071C:Unknown ,, Unknown\n mYJL218W:Unknown ,, Unknown\n mYPR015C:Unknown ,, Unknown\n Cond163:ssn6(haploid)\n mYAP6:bZIP protein,,\n mMSN4:multicopy suppressor of snf1 mutation,zinc finger protein,Nu\nll mutant is viable; msn2 msn4 double deletion mutants exhib\nit higher sensitivity to different stresses, including carbo\nn source starvation, heat shock and severe osmotic and oxida\ntive stresses\n mSTR2:Sulfur TRansfer,cystathionine gamma-synthase,Null mutant is \nviable but unable to turn cysteine into homocysteine. Grows \nwhen supplied with cystathionine.\n mYCR100C:Unknown ,, Unknown\n Cond164:sst2(haploid)\n mYPL280W:Unknown ,, Unknown\n mYDR540C:Unknown ,, Unknown\n Cond13:ase1(**12)\n Cond291:FR901,228\n mDIT1:Disp. for spores & spore viability - required for dityrosine\n accumul. in the outer spore wall (s.w.), s.w. maturation & \nresist. to ether & lytic enzymes. Spore-autonomous function \nin heterozygotes. mRNA is trans. mid/late in s.w. formation,\nfirst enzyme in dityrosine synthesis in the outer layer of t\nhe spore wall pathway, converting L-tyrosine to N-formyl-L-t\nyrosine,lack outermost layer of spore wall\n Cond730:hda1\n mECM4:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mYMR322C:Unknown ,, Unknown\n mSOR1:sorbitol-induced sorbitol dehydrogenase,sorbitol dehydrogena\nse, sorbitol-induced,\n Cond729:sin3\n mFUS1:cell-surface protein required for cell fusion,,Null mutant i\ns viable; in fus1 x fus1 matings there is an interruption of\n the mating process just before cytoplasmic fusion\n mYJL037W:Unknown ,, Unknown\n Cond517:sst2D/wtlog10(intensity)\n mYOR338W:Unknown ,, Unknown\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n mYJL038C:Unknown ,, Unknown\n mYLR042C:Unknown ,, Unknown\n mTHI12:thiamine regulated gene, homologous to nmt1a in Schizosaccha\nromyces pombe; putatively involved in pyrimidine biosynthesi\ns,,\n mYER185W:Unknown ,, Unknown\n mTHI13:Product of gene unknown,,\n mOYE3:Old yellow enzyme,NADPH dehydrogenase,\n mSRY1:Serine Racemase homolog in Yeast,pyridoxal-5'phosphate-depen\ndent enzyme , similar to mouse glial serine racemase,Null mu\ntant is viable\n mYBR147W:Unknown ,, Unknown\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mNIT1:nitrilase,nitrilase,\n mYOR389W:Unknown ,, Unknown\n mPCK1:phosphoenolpyruvate carboxylkinase,phosphoenolpyruvate carbo\nxylkinase,Null mutant is viable.\n mICY2:Interacting with the cytoskeleton,,\n mYEL070W:Unknown ,, Unknown\n mSGA1:intracellular sporulation-specific glucoamylase involved in \nglycogen degradation. Induced during starvation of a/a late \nin sporulation, but dispensable for sporulation,glucoamylase\n,suppression of growth arrest of cdc25\n mADH5:alcohol dehydrogenase isoenzyme V,alcohol dehydrogenase isoe\nnzyme V,\n Cond87:isw1\n Cond871:yhe710-ss\n mYNR073C:Unknown ,, Unknown\n mDAK2:dihydroxyacetone kinase,dihydroxyacetone kinase,Null mutant \nis viable and show no growth defect in normal medium; mutant\n lacking both dak1 and dak2 is sensitive to dihydroxyacetone\n during saline growth\n mSNZ1:Snooze: stationary phase-induced gene family; may be involve\nd in cellular response to nutrient limitation and growth arr\nest,highly conserved 35 kDa protein that shows increased exp\nression after entry into stationary phase,Null mutant is via\nble, sensitive to 6-azauracil and methylene blue.\n Cond88:isw1,isw2\n mSNZ2:Snooze: stationary phase-induced gene family,,hypersporulati\non\n Cond405:Diauxic_Shift_Timecourse_-_0_h\n mYIL172C:Unknown ,, Unknown\n mSNZ3:Snooze: stationary phase-induced gene family,,hypersporulati\non\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYLR312C:Unknown ,, Unknown\n mYHL044W:Unknown ,, Unknown\n Cond293:HU\n mYGR043C:Unknown ,, Unknown\n mSNO1:SNZ1 proximal ORF, stationary phase induced gene,,Null mutan\nt is viable, sensitive to 6-azauracil and methylene blue.\n mSNO2:SNZ2 proximal ORF, stationary phase induced gene,,Null mutan\nt is viable.\n mCOS12:Protein with strong similarity to subtelomerically-encoded p\nroteins including Cos2p, Cos4p, Cos8p, YIR040c, Cos5p, Cos9p\n, and Cos6p,,\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n mSNO3:SNZ3 proximal ORF, stationary phase induced gene family,,Nul\nl mutant is viable.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYDL241W:Unknown ,, Unknown\n Cond250:ymr031w-a\n mECM13:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mMAL32:Part of the complex locus MAL3; functional in S288C; highly \nhomologous to MAL62 from S. carlsbergenesis strain CB11,malt\nase,Defective maltose fermentation\n mTMT1:Trans-aconitate Methyltransferase 1,,\n mGIT1:permease involved in the uptake of glycerophosphoinositol (G\nroPIns),permease involved in the uptake of glycerophosphoino\nsitol (GroPIns),Null mutant is viable, exhibits decreased Gr\noPIns transport\n Cond182:tup1(haploid)\n mMAL33:Part of complex locus MAL3; nonfunctional in S288C, shows ho\nmology to both functional & nonfunctional MAL-activator prot\neins in other Sc strains & to other nonfunctional MAL-activa\ntor sequences from S288C (i.e. MAL33, YPR196W, & YFL052W),MA\nL-activator protein,Defective maltose fermentation\n mFIG1:Factor-Induced Gene 1: expression is induced by the mating p\nheromones, a and alpha factor; required for efficient mating\n,integral membrane protein,Null mutant is viable, deficient \nin mating\n Cond731:hda1 \n mBIO3:biotin biosynthesis,7,8-diamino-pelargonic acid aminotransfe\nrase (DAPA) aminotransferase,\n mYOL162W:Unknown ,, Unknown\n mBIO5:transmembrane regulator of KAPA/DAPA transport,transmembrane\n regulator of KAPA/DAPA transport,\n mPHO89:Probable Na+/Pi symporter,Na+/Pi symporter (putative),Null m\nutant is viable\n mYLR040C:Unknown ,, Unknown\n Cond206:yel044w\n mYGL117W:Unknown ,, Unknown\n Cond727:rpd3\n mACA1:contains an ATF/CREB-like bZIP domain; transcriptional activ\nator,basic leucine zipper (bZIP) transcription factor,\n mYLL055W:Unknown ,, Unknown\n mYFR054C:Unknown ,, Unknown\n mBNA1:biosynthesis of nicotinic acid,3-hydroxyanthranilic acid dio\nxygenase,Null mutant is viable, nicotinic acid auxotroph\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n mYER187W:Unknown ,, Unknown\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n mHXT13:high-affinity hexose transporter,high affinity hexose transp\norter,\n Cond133:rpd3(haploid)\n mHXT15:High-affinity hexose transporter,hexose transporter,\n mHXT16:hexose transporter,hexose permease,\n mYOR391C:Unknown ,, Unknown\n mHXT17:Hexose transporter,hexose transporter,\n mSPO20:DBF2 Interacting Protein; SNAP 25 homolog,DBF2 interacting p\nrotein , SNAP 25 homolog,Null mutant is viable, other mutant\n fails to form spores\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mSNZ3 mSNO1 mYMR322C mSNZ2 mSNO2 mSNO3 mSNZ1
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Computational Genomics Lab, Tel-Aviv uniresity