Module number 649




Database revision : gnsdb28.10
Date : Tue Feb 25 17:02:00 2003
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mADY2:Accumulation of DYads,,Null mutant is viable; forms predomin\nantly asci containing 2 spores (dyads) whensporulated; requi\nred for long-term growth on YPD at 37 degrees C.\n Cond458:YP_raffinose_vs_reference_pool_car-2\n Cond936:12h\n Cond871:yhe710-ss\n mYJL160C:Unknown ,, Unknown\n Cond625:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y12-121\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYLL047W:Unknown ,, Unknown\n Cond385:Hypo-osmotic_shock_-_15_min\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n mYGL081W:Unknown ,, Unknown\n Cond963:t11.5_g/r_ratio\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYIL024C:Unknown ,, Unknown\n mSPO11:Dispensable for mitosis, premeiotic DNA synthesis, spindle p\nole body duplication, meiosis I, meiosis II & spores. Requir\ned for chromosome pairing seen by in situ hybridization, dou\nble strand breaks, synaptonemal complexes.,early meiosis-spe\ncific recombination protein,Null mutant is viable, sporulati\non defective; spo11 executes meiosis I early, is rescued by \nspo13 and is epistatic to rad52 spo13; and is classified as \nan early recombination function. It fails to form any recomb\nination intermediates and is partially suppressed by X-irrad\niation (by induced double strand breaks), in meiosis. The sp\no11-1 temperature sensitive mutant is double strand break-, \nrecombination-, and exhibits tripartite synaptonemal complex\n structures at a restrictive temperature, suggesting synapto\nnemal complex formation may be partially independent of doub\nle strand breaks and recombination. mRNA is induced early in\n meiosis; meiosis-specific regulation is dependent on a URS1\n element within the coding region.\n Cond729:sin3\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRIM4:Regulator of IMe2 expression,RNA-binding protein of the RRM \nclass (putative),Null mutant is viable. Homozygous null dipl\noid fails to sporulate, does not form meiosis I or II spindl\nes, and exhibits reduced expression of early and middle spor\nulation-specific genes. Null mutant is suppressed by hyperac\ntive Ime2p derivative, but not by overexpression IME1\n mSPS1:dispensable for mitosis, involved in middle/late stage of me\niosis, required for spore wall formation,,Null mutant is via\nble\n mSPC29:Nuclear import protein,spindle pole body associated protein,\nNull mutant is inviable\n mSPO16:Early meiotic protein required for efficient spore formation\n,,sporulation defective\n Cond959:t2_g/r_ratio\n mZIP1:Synaptonemal complex protein, component of the central eleme\nnt,,Null mutant is viable and shows defects in meiosis\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond940:6h\n Cond:\n mSHC1:sporulation-specific homolog of csd4,sporulation-specific pr\notein similar to Skt5p,\n Cond965:ndt80_delete_mid_g/r_ratio_\n mYLL030C:Unknown ,, Unknown\n mYSW1:Spore-specific protein,,\n mHOP1:Meiosis-specific protein involved in homologous chromosome s\nynapsis and chiasmata formation,DNA binding protein,decrease\nd levels of meiotic crossing over and intragenic recombinati\non between markers on homologous chromosomes\n Cond727:rpd3\n mRNP1:ribonucleoprotein 1,RNA binding protein (putative),Null muta\nnt is viable\n Cond937:t=0\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond934:8h\n Cond960:t5_g/r_ratio\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n Cond938:2h\n mULP2:Product of gene unknown,,Null mutant is viable but exhibits \ntemperature-sensitive growth, abnormal cell morphology, decr\neased plasmid and chromosome stability, and a severe sporula\ntion defect as well as hypersensitivity to DNA-damaging agen\nts, hydroxyurea, and benomyl. SMT4/ULP2 was also isolated as\n a high copy suppressor of a temperature sensitive mutation \nin MIF2, a putative centromere protein gene\n Cond961:t7_g/r_ratio\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond935:10h\n Cond449:glucose_vs._reference_pool_car-1\n Cond962:t9_g/r_ratio\n mECM23:ExtraCellular Mutant; similar to SRD1,,A Tn3 insertion into \nthis gene causes hypersensitivity to the cell surface polyme\nr perturbing agent calcofluor white.\n Cond958:t0.5_g/r_ratio\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity