Module number 624




Database revision : gnsdb28.10
Date : Tue Feb 25 17:41:54 2003
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mYGR269W:Unknown ,, Unknown\n mYJL211C:Unknown ,, Unknown\n mSFB2:binds to Sed5p and Sec23p by distinct domains,zinc finger pr\notein (putative),\n mBNI4:bud neck involved,required to link Chs3p and Chs4p to the se\nptins,Null mutant is viable, shows delocalized chitin, elong\nated buds, enlarged bud necks\n mSAP30:Hypothetical ORF,,\n mBRE2:Product of gene unknown,,null mutant is sensitive to brefeld\nin A\n mSIP3:Interacts with SNF1 protein kinase,transcriptional activator\n (putative),Null mutant is viable; does not confer snf1 phen\notypes\n mHAT1:histone acetyltransferase,histone acetyltransferase,Null mut\nant is viable\n mSWM1:Spore Wall Maturation 1,,Null mutant completes meiotic nucle\nar division but does not show spore wall maturation\n mPUF4:member of the PUF protein family,,\n mHYR1:Hydroperoxide resistance conferring gene,glutathione-peroxid\nase (putative),Null mutant is hypersensitive to oxidative st\nress\n mBUD2:GTPase-activating protein (GAP) for Rsr1p/Bud1p,GTPase activ\nating protein (GAP) for Rsr1p/Bud1p,Null mutant is viable, w\nith random bud site selection in all cell types\n mYLR171W:Unknown ,, Unknown\n mFYV2:Function required for Yeast Viability on toxin exposure,,K1 \nkiller toxin hypersensitivity\n mYJR097W:Unknown ,, Unknown\n mBEM3:Gtpase-activating protein activity toward the essential bud-\nsite assembly GTPase Cdc42,rho GTPase activating protein (GA\nP),Null mutant is viable.\n mYEL048C:Unknown ,, Unknown\n mLST4:involved in regulated secretion/recycling of nitrogen regula\nted permeases,,very low activity of the nitrogen-regulated p\nermeases Gap1p and Put4p on poor nitrogen sources; lst4-1 be\nhaves as a complete kanMX knockout for the phenotypes tested\n so far\n mYAL045C:Unknown ,, Unknown\n mGFD2:Unknown ,, Unknown\n mYDR179W-A:Unknown ,, Unknown\n mFYV8:Function required for Yeast Viability on toxin exposure,,Nul\nl phenotype is K1 killer toxin hypersensitive\n mYLR077W:Unknown ,, Unknown\n mPDR8:Unknown ,, Unknown\n mMDM1:Intermediate filament protein involved in organelle inherita\nnce,intermediate filament protein,Null mutant is inviable; t\nemperature sensitive mutants display defective transfer of n\nuclei and mitochondria into developing buds at the non-permi\nssive temperature\n mTAD1:Deaminates adenosine-37 to inosine in eukaryotic tRNA-Ala.,t\nRNA-specific adenosine deaminase subunit,Null mutant is viab\nle\n mDLD2:D-lactate dehydrogenase, located in mitochondrial matrix,,Nu\nll mutant is viable\n mYKR106W:Unknown ,, Unknown\n mYOR131C:Unknown ,, Unknown\n mYPL150W:Unknown ,, Unknown\n mABM1:aberrant microtubules,,\n mYBL089W:Unknown ,, Unknown\n mZRC1:Zinc- and cadmium-resistance protein,,Null mutant is viable \nand sensitive to zinc\n mNCR1:Niemann-Pick Type C homologous gene,transmembrane protein (p\nutative),Null mutant is viable.\n mYPL216W:Unknown ,, Unknown\n mRNH70:RNase H(70), a 70 kDa ribonuclease H,ribonuclease H,Null mut\nant is viable.\n mNMD2:Protein involved in decay of mRNA containing nonsense codons\n,,Null mutant is viable, exhibits stabilization of nonsense-\ncontaining mRNAs\n mGPM2:Similar to GPM1 (phosphoglycerate mutase); converts 3-phosph\noglycerate to 2-phosphoglycerate in glycolysis,,Null mutant \nis viable, gpm2 gpm3 double deletion mutants exhibit no synt\nhetic phenotypes\n mYLR143W:Unknown ,, Unknown\n mATF1:Alcohol acetyltransferase,alcohol acetyltransferase,\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n mSMM1:Suppressor of Mitochondrial Mutation in the tRNAasp gene; Di\nhydrouridine synthase 2,tRNA dihydrouridine synthase,Overexp\nression weakly suppresses a mutation affecting the maturatio\nn of mitochondrial tRNA-Asp.\n mYLR252W:Unknown ,, Unknown\n mDPH2:Diptheria toxin resistance protein, required for diphthamide\n biosynthesis,,Null mutant is viable\n mAMD1:putative alpha-mannosidase,alpha-mannosidase (putative),Null\n mutant is viable\n mPNT1:Involved in targeting of proteins to the mitochondrial inner\n membrane; Pentamidine resistance protein,,Null mutant is vi\nable and shows slightly increased susceptibility to pentamid\nine (an anti-Pneumocystis carinii drug) and related compound\ns; confers resistance to pentamidine when present in high co\npy number\n mRNP1:ribonucleoprotein 1,RNA binding protein (putative),Null muta\nnt is viable\n mDPH5:diphthamide biosynthesis,,Null mutant is viable\n mSPL2:Suppressor of plc1-delta. Isolated as a dosage suppressor of\n the temperature-sensitive phenotype of a plc1 null mutant. \nAlso suppresses the hyperosmotic-sensitive phenotype of the \nplc1 null mutant.,,Null mutant is viable and shows no obviou\ns phenotype; spl2-delta plc1-delta double mutant fails to gr\now on SCD complete media, but grows on YPD at 25 degrees C\n mYOR175C:Unknown ,, Unknown\n mALG6:Required for glucosylation in the N-linked glycosylation pat\nhway,glucosyltransferase,Null mutant is viable and defective\n in protein glycosylation.\n mYKL031W:Unknown ,, Unknown\n mYER051W:Unknown ,, Unknown\n mRMD5:Unknown ,, Unknown\n mYDR269C:Unknown ,, Unknown\n mTAT2:Tryptophan permease, high affinity,tryptophan permease, high\n affinity,suppressor of chromosome segregation mutation\n mALG8:adds glucose to the dolichol-linked oligosaccharide precurso\nr prior to transfer to protein,glycosyl transferase,Null mut\nant is viable, secretes under-glycosylated proteins\n mCYC2:Involved in import of cytochrome c into mitochondria,cytochr\nome c mitochondrial import factor,Null mutant is viable. Del\netion of CYC2 leads to accumulation of apocytochrome c in th\ne cytoplasm; strains with deletions of CYC2 still import low\n levels of cytochrome c into mitochondria\n mYMR029C:Unknown ,, Unknown\n mGIS2:GIG3 suppressor,,\n mCNE1:Functions in endoplasmic reticulum protein quality control,c\nalnexin and calreticulin homolog,Null mutant is viable, incr\nease of cell-surface expression of ste2-3p, increase in secr\netion of heterologously expressed mammalian alpha 1-antitryp\nsin\n mYDR008C:Unknown ,, Unknown\n mYPR096C:Unknown ,, Unknown\n mYPR118W:Unknown ,, Unknown\n mYPR038W:Unknown ,, Unknown\n mELG1:enhanced frequency of direct-repeat recombination,,Null muta\nnt is viable, not sensitive to MMS or UV.\n mTRP1:Note that the sequence of TRP1 from strain S228C, which is t\nhe sequence stored in SGD, contains an ochre mutation at cod\non 67.,N-(5'-phosphoribosyl)-anthranilate isomerase,tryptoph\nan requiring\n mYGL007W:Unknown ,, Unknown\n mYFR024C:Unknown ,, Unknown\n mSLK19:synthetic lethal KAR3,leucine zipper (putative),Null mutant \nexibits long astral microtubules, short spindles, bypass mei\nosis I, partial mitotic arrest; synthetic lethal with kar3*,\n loss of both produces mitotic arrest\n mBSD2:metal homeostasis protein; putative membrane protein,,Null m\nutant is viable; suppressor of oxygen toxicity in sod1 mutan\nts, increased sensitivity to copper and cadmium toxicity, el\nevation in copper ion accumulation\n mGEA1:component of a complex guanine nucleotide exchange activity \nfor the ADP-ribosylation factor ARF,GDP/GTP exchange factor,\nMutant exhibits defective ER to Golgi transport; synthetical\nly lethal with gea2::HIS3.\n mYBR071W:Unknown ,, Unknown\n mYLR137W:Unknown ,, Unknown\n mANB1:hypusine containg protein; ANB1 is expressed under anaerobic\n conditions and repressed under aerobic conditions whereas i\nts homolog HYP2 is inversely regulated,translation initiatio\nn factor eIF-5A, anaerobically expressed form,null mutant is\n viable; a double mutant containing disruptions of both ANB1\n and and the highly homologous HYP2 is inviable\n mPTK1:Putative serine/threonine protein kinase,,Mutant shows decre\nase in total polyamine accumulation and resistance to polyam\nine analogs; ptk1 ptk2 double mutant shows virtually abolish\ned high-affinity spermidine transport\n mIMD3:Hypothetical ORF,IMP dehydrogenase homolog,\n mYPL261C:Unknown ,, Unknown\n mYEL006W:Unknown ,, Unknown\n mDIG1:Down-regulator of Invasive Growth, Regulator of Sterile Twel\nve, binds Fus3 and Ste12,MAP kinase-associated protein,Null \nmutant is viable, shows abnormal bud morphology; dig1 dig2 d\nouble mutants show constitutive mating defect and invasive g\nrowth; overexpression causes pheromone resistance\n mSEO1:Suppressor of Sulfoxyde Ethionine resistance,permease (putat\nive),\n mAPS1:Involved in a subset of clathrin functions at the Golgi,clat\nhrin associated protein complex small subunit,Null mutant is\n viable; aps1 mutants demonstrate synthetic effects with chc\n1 alleles\n mYLR414C:Unknown ,, Unknown\n mYNL122C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSIZ1:Sap and mIZ. Contains two known protein motifs: SAP (DNA bin\nding) and MIZ-finger,chromatin protein,Null mutant is viable\n. SIZ1 is a dosage bypass suppressor of an SMT4 deletion. A\n siz1 siz2 deletion has a synthetic phenotype (slow growth).\n mYOR118W:Unknown ,, Unknown\n mYOS9:Unknown ,, Unknown\n mTPO4:Unknown ,, Unknown\n mYOR154W:Unknown ,, Unknown\n mPPH3:protein phosphatase type 2A,protein phosphatase type 2A,Null\n mutant is viable, pph3 pph21 pph22 mutants are inviable\n mYBR174C:Unknown ,, Unknown\n mYNL144C:Unknown ,, Unknown\n mFCY21:identical to FCY2,purine-cytosine permease,\n mMAI1:Unknown ,, Unknown\n mYAR028W:Unknown ,, Unknown\n mYCL049C:Unknown ,, Unknown\n mYOL093W:Unknown ,, Unknown\n mYLR232W:Unknown ,, Unknown\n mSBE22:functionally redundant and similar in structure to SBE2,,syn\nthetic lethal with sbe2 mutation\n mAPL1:beta-adaptin, large subunit of the clathrin-associated prote\nin complex,beta-adaptin , clathrin associated protein comple\nx large subunit,null mutant is viable\n mYBL012C:Unknown ,, Unknown\n mCUP2:Upregulates metallothionein (CUP1) expression in response to\n Cu2+,transcriptional activator,Null mutant is sensitive to \nCu2+\n mYMR320W:Unknown ,, Unknown\n mAPL5:Delta-like subunit of the yeast AP-3 complex which functions\n in transport of alkaline phosphatase to the vacuole via the\n alternate pathway, suppressor of loss of casein kinase 1 fu\nnction,clathrin assembly complex AP-3 adaptin component delt\na-like subunit,Null mutant is viable, rescues yck1,yck2 doub\nle mutant\n mYBL062W:Unknown ,, Unknown\n mAPL6:beta3-like subunit of the yeast AP-3 complex which functions\n in transport of alkaline phosphatase to the vacuole via the\n alternate pathway, suppressor of loss of casein kinase 1 fu\nnction,clathrin assembly complex beta adaptin component (put\native),Null mutant is viable, null rescues yck1 yck2 double \nmutant\n mYGL226W:Unknown ,, Unknown\n mYOR300W:Unknown ,, Unknown\n mMSB3:Multicopy Suppressor of Bud Emergence,GTPase activating prot\nein (GAP) for Ypt6,Null mutant is viable. msb3/msb4 double \nmutant exhibits slow growth and disorganized actin cytoskele\nton\n mARN1:Product of gene unknown,,\n mYGL262W:Unknown ,, Unknown\n mELA1:similar to mammalian elongin A, interacts with elongin C,elo\nngin A transcription elongation factor,viable\n mRCE1:Protease involved in ras and a-factor terminal proteolysis,p\nrotease,Null mutant is viable, has defects in Ras localizati\non and signaling, and suppresses the activated phenotype of \nthe RAS2val19 allele\n mYGL161C:Unknown ,, Unknown\n mNRG2:homologue of NRG1,NRG1 homolog,Null mutant is viable with no\n detected phenotypes\n mYDR220C:Unknown ,, Unknown\n mRGA2:contains a Rho-GAP domain and two LIM domains, similar to Rg\na1p and all known Rho-GAPs,Rho-GTPase Activating Protein,Nul\nl mutants are viable but increase the restrictive temperatur\ne of a cdc24-4 strain and increase the constitutive activati\non of the pheromone response pathway in conjungtion with mut\nations in RGA1 and BEM3; overexpression of RGA2 causes a dec\nrease in the restrictive temperature of a cdc42-1 strain\n mKRE20:Killer toxin REsistant,,Null mutant is viable but exhibits K\n1 killer toxin resistance.\n mYDL050C:Unknown ,, Unknown\n mGSG1:Probably has role late in meiosis following DNA replication,\n,homozygous diploids do not sporulate (no asci)\n mYDL180W:Unknown ,, Unknown\n mYNL319W:Unknown ,, Unknown\n mCIN2:involvement in microtubule function,tubulin folding cofactor\n C,Null mutant is viable but shows supersensitivity to benom\nyl and nocodazole, cold sensitivity, defects in karyogamy, a\nnd increased rates of chromosome loss; shows genetic interac\ntion with tubulin mutations\n mFOB1:The gene product is essential for both DNA replication fork \nblocking and recombinational hotspot activities.,DNA replica\ntion fork blocking protein,Loss of replication fork blocking\n and recombinational hotspot activities.\n mKGD2:dihydrolipoyl transsuccinylase component of alpha-ketoglutar\nate dehydrogenase complex in mitochondria,alpha-ketoglutarat\ne dehydrogenase complex dihydrolipoyl transsuccinylase compo\nnent,Null mutant is viable but is respiratory deficient (pet\n-), and its mitochondria are unable to catalyze the reductio\nn of NAD+ by alpha-ketoglutarate\n mABP1:Actin binding protein,actin binding protein,Null mutant is v\niable\n mBIT1:Unknown ,, Unknown\n mPMC1:May be involved in depleting cytosol of Ca2+ ions,Ca2+ ATPas\ne (putative),Null mutant is viable but fails to grow in high\n Ca2+ medium; this death in high calcium is suppressed by mu\ntations in calcineurin (CNA1, CNA2, CNB1) and calmodulin (CM\nD1); pmc1 vcx1 double mutant is even more sensitive to Ca2+\n mMDM32:Unknown ,, Unknown\n mHMS2:High-copy mep2 suppressor,heat shock transcription factor ho\nmolog,Null mutant is viable; multicopy expression suppresses\n the pseudohyphal defect of mep2/mep2 strains\n mAPM3:Mu3-like subunit of the yeast AP-3 complex which functions i\nn transport of alkaline phosphatase to the vacuole via the a\nlternate pathway,clathrin associated protein complex medium \nsubunit,Null mutant is viable, even combined with apm1 and a\npm2\n mAPM4:Clathrin associated protein, medium subunit,clathrin associa\nted protein complex medium subunit,\n mYBL006C:Unknown ,, Unknown\n mRAS1:ras proto-oncogene homolog,ras homolog,\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n mYOR345C:Unknown ,, Unknown\n mYNL022C:Unknown ,, Unknown\n mRXT1:Unknown ,, Unknown\n mTRK1:180 kDa high affinity potassium transporter,180 kDa high aff\ninity potassium transporter,Null mutant is viable, requires \nadded potassium; trk1 trk2 double mutants are viable\n mYDR119W:Unknown ,, Unknown\n mYPL176C:Unknown ,, Unknown\n mMNR2:Product of gene unknown,,overexpression overcomes manganese \ntoxicity\n mADK2:Adenylate kinase (mitochondrial GTP:AMP phosphotransferase),\nadenylate kinase , mitochondrial GTP:AMP phosphotransferase \n, adenylate kinase , mitochondrial GTP:AMP phosphotransferas\ne,null mutant is viable\n mJNM1:coiled-coil domain protein required for proper nuclear migra\ntion during mitosis (but not during conjugation),,Null mutan\nt is viable but is cold-sensitive\n mYEL059W:Unknown ,, Unknown\n mMAK3:N-acetyltransferase,N-acetyltransferase,deficient in mainten\nance of killer\n mYDR112W:Unknown ,, Unknown\n mSTD1:interacts with the SNF1 protein kinase and TBP in two-hybrid\n and in in vitro binding studies,MTH1 homolog,Null mutant is\n viable, no defects in mating or sporulation. Suppressor of \nTBP deletion; multicopy suppressor of SNF; std1-mth1 has def\nective glucose derepression and sporulation\n mGOT1:Golgi Transport,membrane protein,Null mutant is viable but e\nxhibits ER to Golgi transport defects in vitro. got1 is synt\nhetically lethal with mutations in sft2; the got1 sft2 doubl\ne mutant exhibits defects in transport to the Golgi complex.\n mYBR220C:Unknown ,, Unknown\n mMSS1:May play a part in mitochondrial translation,GTPase (putativ\ne),respiratory deficient in presence of pr454 mutation in mi\ntochondrial 15S rRNA; block in splicing of mitochondrial int\nrons\n mZRG8:Zinc regulated gene,,\n mSIF2:Sir4p-Interacting Factor,,Null mutant is viable, exhibits in\ncreased telomeric silencing\n mPPR1:Positive regulator of URA1 and URA3,zinc finger transcriptio\nn factor of the Zn(2)-Cys(6) binuclear cluster domain type,N\null mutant is viable, deficient in pyrimidine biosynthetic p\nathway\n mYDL110C:Unknown ,, Unknown\n mYDR374C:Unknown ,, Unknown\n mYLR169W:Unknown ,, Unknown\n mSPP1:YPL138C,,\n mELC1:similar to mammalian elongin C, interacts with elongin A,elo\nngin C transcription elongation factor,\n mCLG1:cyclin-like protein that interacts with Pho85p in affinity c\nhromatography,,Null mutant is viable\n mYER186C:Unknown ,, Unknown\n mOPI1:Negative regulator of phospholipid biosynthesis,,The null mu\ntant is viable but constitutively accumulates INO1 mRNA.\n mYPL184C:Unknown ,, Unknown\n mYOR055W:Unknown ,, Unknown\n mYDL073W:Unknown ,, Unknown\n mMDR1:Mac1-dependent regulator,GTPase activating protein (GAP) fo\nr Ypt6,Null mutant is viable\n mSMY1:not believed to act as a kinesin, colocalizes with Myo2p,kin\nesin heavy chain homolog,high copy suppressor of myosin\n mENT1:epsin N-terminal homology-containing protein,,Null mutant is\n viable, synthetically lethal with ent2 (YLR206w). ent1/2 do\nuble mutants have endocytosis and actin cytoskeleton defects\n.\n mAPG7:autophagy,,Null mutant is viable, defective in autophagy\n mYPL039W:Unknown ,, Unknown\n mYCR076C:Unknown ,, Unknown\n mSGE1:multi-copy suppressor of gal11 null; member of drug-resistan\nce protein family,,Null mutant is viable; shows decreased ex\npression of galactose-inducible genes; shows increased sensi\ntivity to crystal violet\n mENT5:Unknown ,, Unknown\n mYOL046C:Unknown ,, Unknown\n mPUS7:Unknown ,, Unknown\n mYNR040W:Unknown ,, Unknown\n mYMR258C:Unknown ,, Unknown\n mFIN1:Cell cycle-dependent filament between nuclei,cell cycle-depe\nndent filament between nuclei,Null mutant is viable; overpro\nduction is lethal in haploids and strongly inhibits growth i\nn diploids.\n mMIS1:mitochondrial C1-tetrahydroflate synthase,C1-tetrahydrofolat\ne synthase,Null mutant is viable, exhibits no apparent defec\nts in cell growth\n mIDS2:IME2-Dependent Signalling,,Null mutations reduce or abolish \nthe ability of IME2p to activate expression of early, middle\n, and late meiotic genes. Recessive and null ids2 mutants pr\nevent toxicity of Ime2p expression in rad52 haploids, but do\n not affect Ime2p polypeptide accumulation.\n mGDH1:NADP-specific glutamate dehydrogenase,NADP-specific glutamat\ne dehydrogenase,Null mutant is viable\n mTPK3:Involved in nutrient control of cell growth and division,cAM\nP-dependent protein kinase catalytic subunit,Null mutant is \nviable, tpk1 tpk2 tpk3 triple mutant is inviable\n mYNL089C:Unknown ,, Unknown\n mGDH2:NAD-dependent glutamate dehydrogenase,NAD-dependent glutamat\ne dehydrogenase,Null mutant is viable, grows very poorly on \nglutamate as a nitrogen source\n mSWD1:YAR003W,,\n mVAM7:Regulator of vacuolar morphogenesis,heptad repeat motif , hy\ndrophilic protein,Null mutant is viable, exhibits prominent \nlarge vacuoles\n mLYP1:lysine permease,lysine permease,\n mSWD3:YBR175W,,\n mYKL174C:Unknown ,, Unknown\n mVTC3:Phosphate metabolism; transcription is regulated by PHO syst\nem,polyphosphate synthetase (putative),Null nutant is viable\n; no polyphosphate accumulation in a vtc2(phm1)/vtc3(phm2) d\nouble disruptant\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n mYPL004C:Unknown ,, Unknown\n mPHO87:May collaborate with Pho86p and Pho84p in inorganic phosphat\ne uptake; protein contains 12 predicted transmembrane domain\ns,phosphate permease,Null mutant is viable; pho86 pho87 doub\nle mutant constitutively synthesizes repressible acid phosph\natase and is aresenate-resistant\n mYOR325W:Unknown ,, Unknown\n mFIG4:FIG4 expression is induced by mating factor.,,Null mutant is\n viable, mating defective\n mYHL012W:Unknown ,, Unknown\n mYPR064W:Unknown ,, Unknown\n mYTA6:Member of CDC48/PAS1/SEC18 family of ATPases,AAA ATPase,\n mYPL170W:Unknown ,, Unknown\n mYMR157C:Unknown ,, Unknown\n mYPL033C:Unknown ,, Unknown\n mGDA1:converts nucleoside diphosphates to nucleoside monophosphate\ns to recycle nucleosides and promote transport of additional\n nucleotide sugars into golgi,guanosine diphosphatase of Gol\ngi membrane,Null mutant is viable and has partial block in m\nannosylation of proteins and sphingolipids\n mAPG13:autophagy,,Defective in autophagy\n mSHR5:Involved in RAS localization and palmitoylation,,Null mutant\n is viable; exhibits normal palmityltransferase activity in \nvitro and attenuates Ras function in cells with mutant Ras2 \nproteins that are not farnesylated or palmitoylated; shr5 mu\ntation originally isolated as suppressor of Ras function\n mSUR1:Involved in maintenance of phospholipid levels,integral memb\nrane protein , similar to YBR161w, Hoc1p, and Och1p , integr\nal membrane protein , similar to YBR161w, Hoc1p, and Och1p ,\n integral membrane protein , similar to YBR161w, Hoc1p, and \nOch1p,Null mutant is viable, calcium sensitive at 37 degrees\n C on YPD but calcium tolerant at 26 degrees C, accumulates \ngreatly reduced levels of several mannosylated sphingolipids\n; sur1 mutations have been isolated based on their ability t\no suppress certain phenotype of rvs161 mutants including red\nuced viability upon starvation and sensitivies to unrelated \ndrugs; SUR1 is a high copy suppressor of the calcium sensiti\nvity of csg2 mutants\n mAPG16:autophagy,,Null mutant is viable, defective in autophagy\n mDAL7:allantoin pathway,malate synthase 2,Null mutant is viable\n mYOR246C:Unknown ,, Unknown\n mCUE1:Cue1p assembles with Ubc7p. Cue1p recruits Ubc7p to the cyto\nsolic surface of the endoplasmic reticulum. Assembly with Cu\ne1p is a prerequisite for the function of Ubc7p,Ubc7p bindin\ng and recruitment protein,Null mutant is viable and shows st\nabilization of ER degradation substrates\n mDSE3:Hypothetical ORF,,\n mHMG1:3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase is\nozyme,3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reduct\nase isozyme,Null mutant is viable, sensitive to compactin, a\n competitive inhibitor of HMG-CoA reductase; hmg1 hmg2 doubl\ne deletion mutants are inviable\n mCUE2:Unknown ,, Unknown\n mBNA4:Unknown ,, Unknown\n mFYV14:Function required for Yeast Viability on toxin exposure,,Nul\nl mutant is viable but exhibits K1 killer toxin hypersensiti\nvity.\n mYBR062C:Unknown ,, Unknown\n mMMP1:S-MethylMethionine Permease,high affinity S-methylmethionine\n permease,Null mutant is viable but is unable to use S-methy\nlmethionine as a sulfur source\n mKAP114:KAryoPherin (collective name for homologous family of nuclea\nr transport receptors) of approximately 114kD,,The null muta\nnt is viable.\n mRER1:Protein involved in retention of membrane proteins, includin\ng Sec12p, in the ER; localized to Golgi, where it may functi\non in returning membrane proteins to the ER,,Null mutant is \nviable and shows mislocalization of transmembrane proteins t\nhat are normally retained in the early secretory compartment\ns\n Cond521:fus3-K42Dą50nMaF,30minlog10(intensity)\n mCRN1:coronin, an actin-binding protein originally identified in D\nictyostelium,Dictyostelium and human actin-binding protein c\noronin homolog,Null mutant is viable\n mSCW10:Soluble Cell Wall protein,soluble cell wall protein,Null mut\nant is viable.\n mYMR209C:Unknown ,, Unknown\n mSWD1 mSWD3 mAPM3 mAPL5 mFYV14 mIMD3 mGDH2 mELA1 mHAT1 mYPL004C mYTA6 mYPL150W mHTA1 mKAP114 mYGL161C mVAM7
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity