Module number 619




Database revision : gnsdb28.10
Date : Tue Feb 25 17:40:08 2003
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Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n mMCD1:Mitotic Chromosome Determinant; similar to S. pombe RAD21; m\nay function in chromosome morphogenesis from S phase through\n mitosis,,Null mutant is inviable; temperature sensitive mut\nants are defective in mitotic sister chromatid cohesion and \nmitotic chromosome condensation; multicopy suppressor of smc\n1-2 mutation\n mPOL1:Required for mitotic DNA synthesis, premeiotic DNA synthesis\n, recombination, and full sporulation,DNA polymerase I alpha\n subunit p180,Null mutant is inviable. pol1(ts) mutants show\n blocked cell division at 36 degrees C\n Cond541:fus3D+50nMaF,30min/wtlog10(intensity)\n mTOS4:Hypothetical ORF,,\n Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond798:Ca30'\n Cond548:cln3-2\n Cond578:cdc15_130\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond735: Cond740: Cond513:GAL-STE11-4,3hrs.gallog10(intensity)\n Cond504:wtħ50nMaF,90minlog10(intensity)\n mCLB5:role in DNA replication during S phase; additional functiona\nl role in formation of mitotic spindles along with Clb3 and \nClb4,B-type cyclin,Null mutant is viable, but has an extende\nd S phase\n mYBR070C:Unknown ,, Unknown\n Cond579:cdc15_140\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n Cond561:alpha70\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n mYLR049C:Unknown ,, Unknown\n mCDC6:Protein involved in initiation of DNA replication,pre-initia\ntion complex component,arrest at initiation of S phase\n Cond505:wtħ50nMaF,120minlog10(intensity)\n mCDC47:Essential for initiation of DNA replication,,Null mutant is \ninviable, at nonpermissive temperature cdc47(ts) mutants arr\nest with a large bud and a single nucleus\n Cond733: Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond562:alpha77\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n Cond748: mCLN2:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest; dominant mutation advances the G(sub)1- to\n S- phase transition and impairs ability of cells to arrest \nin G(sub)1 phase in response to external signals\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond530:GAL-BNI1D,3hrs.gallog10(intensity)\n Cond568:alpha119\n Cond753: mYCL022C:Unknown ,, Unknown\n mYPL267W:Unknown ,, Unknown\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n mMCM3:Member of complex that acts at ARS's to initiate replication\n,,Null mutant is inviable, at nonpermissive temperature mcm3\n(ts) mutants arrest with a large bud and a single nucleus an\nd exhibit a high rate of recombination; mcm3 mutants are def\nective in minichromosome maintenance; mcm3-1 cdc45-1 mutants\n are synthetically lethal\n Cond553:alpha14\n Cond752: Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n Cond749: Cond557:alpha42\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n Cond65:fus3(haploid)\n mYOR066W:Unknown ,, Unknown\n Cond797:Ca15'\n Cond502:wtħ50nMaF,45minlog10(intensity)\n Cond54:erg3(haploid)\n Cond581:cdc15_160\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n Cond572:cdc15_70\n Cond558:alpha49\n mYOR263C:Unknown ,, Unknown\n Cond734: Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n mCDC21:cell division cycle blocked at 36 degree C,thymidylate synth\nase,defective in continued replication during S phase of the\n cell cycle; temperature-sensitive thymidylate auxotroph\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n mKCC4:involved in septin organization,S. pombe Nim1 homolog , prot\nein kinase,Null mutant is viable\n mYJL195C:Unknown ,, Unknown\n Cond554:alpha21\n mENB1:Siderophore transporter for enterobactin; AFT1 regulon,enter\nobactin transporter,Null mutants are viable but are unable t\no take up and utilize iron from enterobactin\n Cond738:90\n Cond571:cdc15_50\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond737: Cond747: Cond366:dtt_120_min_dtt-2\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n mDSE3:Hypothetical ORF,,\n mSVS1:involved in vanadate resistance,,Null mutant is viable, show\ns increased sensitivity to vanadate, but not other metallic \nions or drugs\n Cond570:cdc15_30\n mRNR1:ribonucleotide reductase,ribonucleotide reductase, large (R1\n) subunit,Null mutant is inviable\n Cond736: Cond503:wtħ50nMaF,60minlog10(intensity)\n Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond559:alpha56\n mYRO2:Homolog to HSP30 heat shock protein Yro1p,,\n mSWE1:protein kinase homolog,protein kinase homolog,Null mutant is\n viable\n Cond750: Cond510:fus3Dħ50nMaF,30minlog10(intensity)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n Cond549:clb2-2\n mYOX1:Homeodomain protein that binds leu-tRNA gene,homeobox-domain\n containing protein,Null mutant is viable\n mCDC47 mMCM3
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Computational Genomics Lab, Tel-Aviv uniresity