Module number 54




Database revision : gnsdb28.10
Date : Tue Feb 25 17:35:56 2003
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Cond158:sir2\n Cond277:AUR1(tetpromoter)\n Cond476:GCN4C/GCN4(R4760/R6257)\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n Cond221:yer083c\n Cond104:npr2\n mLYS20:homocitrate synthase, highly homologous to YDL131W,YDL131W (\nLYS21) homolog , homocitrate synthase,Null mutant is viable,\n is able to grow on minimal media, and exhibits reduced but \nsignificant homocitrate synthase activity\n Cond260:ymr237w\n Cond29:clb2\n Cond130:rml2(**13)\n mYCL042W:Unknown ,, Unknown\n Cond13:ase1(**12)\n Cond137:rpl34a(**9)\n Cond537:kss1D/wtlog10(intensity)\n Cond730:hda1\n Cond190:vps8\n Cond140:rps24a(**9)\n Cond244:ymr010w\n mSDT1:suppressor of deletion of TFIIS,,null mutant is viable, but \nis sensitive to 6-azauracil\n Cond90:jnm1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n Cond30:clb6\n Cond53:erg2\n Cond142:rps27b(**11)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n mPYC2:converts pyruvate to oxaloacetate,pyruvate carboxylase,Null \nmutant is viable; pyc1 pyc2 double mutant is unable to grow \non glucose as sole carbon source unless aspartate is added t\no the medium\n Cond184:ubr1\n Cond123:rad57\n Cond6:anp1\n mSPL2:Suppressor of plc1-delta. Isolated as a dosage suppressor of\n the temperature-sensitive phenotype of a plc1 null mutant. \nAlso suppresses the hyperosmotic-sensitive phenotype of the \nplc1 null mutant.,,Null mutant is viable and shows no obviou\ns phenotype; spl2-delta plc1-delta double mutant fails to gr\now on SCD complete media, but grows on YPD at 25 degrees C\n Cond298:Terbinafine\n mHOR7:hyperosmolarity-responsive gene,,\n Cond279:ERG11(tetpromoter)\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond85:imp2\n Cond201:yel008w\n mYAP1801:Yeast Assembly Polypeptide, member of AP180 protein family, \nbinds Pan1p and clathrin,,Null mutant is viable\n Cond229:yhr011w(**14)\n Cond216:yer044c(haploid)\n mPEX21:Peroxin; Pex18p and Pex21p are partially functionally redund\nant.,peroxin,Null mutant is viable.\n Cond86:imp2'(**12)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond226:yhl029c\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond287:2-deoxy-D-glucose\n Cond478:WT+/-10mM3AT(R491)\n mTRP2:anthranilate synthase Component I,anthranilate synthase comp\nonent I,tryptophan requiring\n Cond145:rts1\n Cond144:rtg1\n Cond71:gln3\n Cond43:dot4\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond114:pet117\n Cond132:rnr1(haploid**9)\n Cond171:ste24(haploid)\n Cond26:cka2\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond175:swi4\n Cond69:gcn4\n Cond94:kss1(haploid)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYJR111C:Unknown ,, Unknown\n Cond250:ymr031w-a\n mPHO84:inorganic phosphate transporter, transmembrane protein,inorg\nanic phosphate transporter,Null mutant is viable\n Cond27:ckb2\n Cond394:aa_starv_6_h\n Cond731:hda1 \n Cond162:spf1\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond294:Itraconazole\n Cond348:1mM_Menadione_(40_min)_redo\n Cond299:Tunicamycin\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond274:yor080w(**3)\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mVHT1:vitamin H transporter,H+-biotin symporter,reduced biotin upt\nake, reduced levels of protein biotinylation\n Cond392:aa_starv_2_h\n Cond39:dig1\n Cond160:sir4\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n mHIS1:involved in the first step of histidine biosynthesis,ATP pho\nsphoribosyltransferase,Null mutant is viable and requires hi\nstidine\n
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Computational Genomics Lab, Tel-Aviv uniresity