Module number 43




Database revision : gnsdb28.10
Date : Tue Feb 25 17:34:39 2003
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Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n mHSP104:involved in thermal and ethanol tolerance, inheritance of [P\nSI+], and reactivation of mRNA splicing after heat shock,hea\nt shock protein 104,Null mutant is viable and defective in i\nnduced thermotolerance\n Cond826:tlc1_Expt.1_Passage_7\n Cond141:rps24a(haploid)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond548:cln3-2\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response.  Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n mKAR2:Involved in translocation of nascent polypeptides across the\n ER membrane,HSP70 family , mammalian BiP (GPR78) homolog , \nHSP70 family , mammalian BiP (GPR78) homolog,null mutants ar\ne inviable; other mutants block karyogamy (nuclear fusion) d\nuring mating\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond834:tlc1_Expt.2_Passage_6\n Cond579:cdc15_140\n Cond976:F82G_1_mM_1NaPP1\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond382:1M_sorbitol_-_90_min\n mTSL1:123 kD regulatory subunit of trehalose-6-phosphate synthase/\nphosphatase complex; homologous to TPS3 gene product,similar\n to TPS3 gene product , trehalose-6-phosphate synthase/phosp\nhatase complex 123 kDa regulatory subunit,Null mutant is via\nble\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond373:1.5_mM_diamide_(40_min)\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond376:1.5_mM_diamide_(90_min)\n Cond318:37C_to_25C_shock_-_60_min\n Cond673:DES460_(wild_type)_+_heat_20_min\n mHCH1:high copy Hsp90 supressor,,Null mutant is viable; when overe\nxpressed, HCH1 is an allele-specific suppressor of hsp82 ts \nmutants\n Cond722:t2+SSD1,H44\n Cond312:Heat_Shock_015_minutes_hs-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond306:Heat_Shock_60_minutes_hs-1\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae.  Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond74:hat2\n Cond825:tlc1_Expt.1_Passage_6\n mYLR217W:Unknown ,, Unknown\n Cond760:Heat_15'\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond581:cdc15_160\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond572:cdc15_70\n Cond422:YPD_stationary_phase_2_h_ypd-1\n Cond972:anc1\n Cond358:2.5mM_DTT_060_min_dtt-1\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n mSTI1:Heat shock protein also induced by canavanine and entry into\n stationary phase,heat shock protein also induced by canavan\nine and entry into stationary phase,Null mutant is viable bu\nt shows slow growth at high or low temperatures; shows synth\netic interactions with hsp82, cpr7, kin28 and sba1\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond374:1.5_mM_diamide_(50_min)\n Cond706:gal2gal80-gal\n Cond370:1.5_mM_diamide_(10_min)\n Cond571:cdc15_50\n Cond634:DES460_+_0.02%_MMS_-_15_min\n SSD1.ANC1: Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond325:29C_to_33C_-_5_minutes\n Cond282:IDI1(tetpromoter)\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond975:WT_1_mM_1NaPP1\n Cond742: Cond461:21_deg_growth_ct-1\n Cond828:tlc1_Expt.1_Passage_9\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Cond564:alpha91\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n mHSC82:constitutively expressed heat shock protein,chaperonin,Null \nmutant is viable at 25 degrees C; ability to grow at higher \ntemperatures varies with gene copy number\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond11:arg5,6\n Cond837:tlc1_Expt.2_Passage_9__\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond332:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_5_minutes\n mHSP82:82 kDa heat shock protein; homolog of mammalian Hsp90,heat s\nhock protein 90 , mammalian Hsp90 homolog , heat shock prote\nin 90 , mammalian Hsp90 homolog,Null mutant is viable at 25 \ndegrees C; ability to grow at higher temperatures varies wit\nh gene copy number\n Cond368:dtt_480_min_dtt-2\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond836:tlc1_Expt.2_Passage_8\n Cond316:37C_to_25C_shock_-_30_min\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond462:25_deg_growth_ct-1\n Cond301:Heat_Shock_10_minutes_hs-1\n Cond982:pho85D_10_mM_1NaPP1_\n Cond369:1.5_mM_diamide_(5_min)\n Cond824:tlc1_Expt.1_Passage_5\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond331:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_30_minutes\n Cond586:cdc15_210\n Cond375:1.5_mM_diamide_(60_min)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n Cond323:heat_shock_29_to_37,_20_minutes\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt.  Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond286:YEF3(tetpromoter)\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n Cond633:DES460_+_0.02%_MMS_-_5_min\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond820:tlc1_Expt.1_Passage_1\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond588:cdc15_230\n Cond827:tlc1_Expt.1_Passage_8\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n Cond317:37C_to_25C_shock_-_45_min\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond273:yor078w\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mCPR6:a cyclophilin related to the mammalian CyP-40; physically in\nteracts with RPD3 gene product,cyclophilin 40 , peptidyl-pro\nlyl cis-trans isomerase (PPIase),Null mutant is viable, has \nnormal growth rate\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond625:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y12-121\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Cond835:tlc1_Expt.2_Passage_7\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mALD4:Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equa\nlly well. (sold by SIGMA under the catalogue number A5550, a\nccording to A. Blomberg).,aldehyde dehydrogenase,\n Cond359:2.5mM_DTT_090_min_dtt-1\n Cond642:DES459_(mec1-)_+_0.02%_MMS_-_30_min\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond823:tlc1_Expt.1_Passage_4\n Cond775:Alkali_80'\n mAHP1:alkyl hydroperoxide reductase,alkyl hydroperoxide reductase,\nhypersensitive to tert-butyl hydroperoxide\n mAHA1:Unknown ,, Unknown\n Cond319:37C_to_25C_shock_-_90_min\n Cond554:alpha21\n Cond398:Nitrogen_Depletion_4_h\n Cond372:1.5_mM_diamide_(30_min)\n Cond876:zero2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond575:cdc15_100\n Cond283:KAR2(tetpromoter)\n Cond324:heat_shock_33_to_37,_20_minutes\n Cond327:29C_to_33C_-_30_minutes\n Cond574:cdc15_90\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond543:rst1Drst2Dtec1D/wtlog10(intensity)\n Cond831:tlc1_Expt.2_Passage_3\n Cond576:cdc15_110\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast.  Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond392:aa_starv_2_h\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond307:Heat_Shock_80_minutes_hs-1\n Cond577:cdc15_120\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n mCPR6 mHSP82 mSTI1

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Computational Genomics Lab, Tel-Aviv uniresity