Module number 385




Database revision : gnsdb28.10
Date : Tue Feb 25 17:37:38 2003
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mSLZ1:sporulation-specific protein with a leucine zipper motif, re\ngulated by the transcription factor Ume6 and expressed early\n in meiosis,,\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond871:yhe710-ss\n mPBP2:Overexpression confers resistance to the antimalarial drug m\nefloquine,,Null mutant is viable\n Cond944:SK1_ume6_YPA\n Cond462:25_deg_growth_ct-1\n Cond405:Diauxic_Shift_Timecourse_-_0_h\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond963:t11.5_g/r_ratio\n Cond378:1M_sorbitol_-_15_min\n mYNL116W:Unknown ,, Unknown\n Cond941:SK1_YPD\n Cond328:33C_vs._30C_-_90_minutes\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond729:sin3\n Cond810:Na45'\n Cond364:dtt_030_min__dtt-2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond959:t2_g/r_ratio\n Stress.WeakCold:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mREC114:meiosis-specific recombination gene; dispensable for mitotic\n recombination and axial elements in meiosis but required fo\nr synaptonemal complexes, meiotic recombination, and spore v\niability; classified as an early recombination gene,early sp\norulation protein,reduced meiotic recombination, rec114 muta\nnts execute meiosis I early, are rescued by spo13 and are ep\nistatic to rad52 spo13\n Cond940:6h\n Cond:\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond942:SK1ume6_YPD\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond633:DES460_+_0.02%_MMS_-_5_min\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mHOP1:Meiosis-specific protein involved in homologous chromosome s\nynapsis and chiasmata formation,DNA binding protein,decrease\nd levels of meiotic crossing over and intragenic recombinati\non between markers on homologous chromosomes\n Cond727:rpd3\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond948:W303_ume6_YPA_\n Cond126:ras1(haploid)\n Cond937:t=0\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond934:8h\n mIME2:Positive regulator of meiosis, dispensable for mitosis, stim\nulates early, middle and late gene expression and negatively\n regulates IME1,,Null mutant is viable, homozygous null muta\nnts are sporulation defective. High copy IME2 stimulates mei\notic recombination without starvation and permits meiosis in\n an ime1 null background\n Cond960:t5_g/r_ratio\n mTID3:Product of gene unknown,,Null mutant is inviable\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mYDR374C:Unknown ,, Unknown\n mMEK1:Disp. for chr. pairing & chr. condensation seen by in situ h\nybrid. Required for full double strand breaks, normal length\n synaptonemal complexes, meiotic recomb. & spore viability. \nmek1 is rescued by spo13 & in early recomb. function,meiosis\n-specific serine/threonine protein kinase,Null mutant is via\nble, however diploids homozygous for a mek1 null mutation pr\noduce only low percentages of viable spores, reduced spore v\niability is rescued by spo13 mutations\n Cond938:2h\n mULP2:Product of gene unknown,,Null mutant is viable but exhibits \ntemperature-sensitive growth, abnormal cell morphology, decr\neased plasmid and chromosome stability, and a severe sporula\ntion defect as well as hypersensitivity to DNA-damaging agen\nts, hydroxyurea, and benomyl. SMT4/ULP2 was also isolated as\n a high copy suppressor of a temperature sensitive mutation \nin MIF2, a putative centromere protein gene\n Cond961:t7_g/r_ratio\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mYLR445W:Unknown ,, Unknown\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond935:10h\n Cond962:t9_g/r_ratio\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mAPG1:Required for autophagy,protein kinase,Defective in autophagy\n; loses viability more rapidly than wild type during nitroge\nn starvation; defective in vacuolar protein degradation duri\nng nitrogen starvation; defective in sporulation\n Cond958:t0.5_g/r_ratio\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity