Module number 3230




Database revision : gnsdb28.10
Date : Tue Feb 25 17:15:55 2003
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mSPR3:a sporulation-specific homologue of the yeast CDC3/10/11/12 \nfamily of bud neck microfilament genes; regulated by ABFI,,N\null mutant is viable\n mYKR015C:Unknown ,, Unknown\n mCRR1:CRH-Related,,\n Cond448:galactose_vs._reference_pool_car-1\n mUBC11:homolog of ubiquitin carrier protein E2-C,,Null mutant is vi\nable\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond183:ubp8\n Cond362:dtt_000_min__dtt-2\n mDIT1:Disp. for spores & spore viability - required for dityrosine\n accumul. in the outer spore wall (s.w.), s.w. maturation & \nresist. to ether & lytic enzymes. Spore-autonomous function \nin heterozygotes. mRNA is trans. mid/late in s.w. formation,\nfirst enzyme in dityrosine synthesis in the outer layer of t\nhe spore wall pathway, converting L-tyrosine to N-formyl-L-t\nyrosine,lack outermost layer of spore wall\n mSMA2:SPOrulation deficient,,Undergoes both meiotic nuclear divisi\nons without chromosome missegregation but fails to form spor\nes , undergoes meiotic nuclear divisions but does not form s\npores\n mPES4:Suppressor of DNA polymerase epsilon mutation,poly(A) bindin\ng protein , similar to YHR015W,\n Cond99:med2(haploid)\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYJL037W:Unknown ,, Unknown\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYNL019C:Unknown ,, Unknown\n mSPS1:dispensable for mitosis, involved in middle/late stage of me\niosis, required for spore wall formation,,Null mutant is via\nble\n mYKR005C:Unknown ,, Unknown\n mSPS2:Middle/late gene of meiosis,,Null mutant is viable\n Cond940:6h\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond:\n mGAS4:Unknown ,, Unknown\n mFRM2:Protein involved in the integration of lipid signaling pathw\nays with cellular homeostatis,,Null mutant is viable and sen\nsitive to arachidonic acid\n mSPO74:Protein involved in sporulation,,undergoes meiotic nuclear d\nivisions but does not form spores\n mYJL038C:Unknown ,, Unknown\n Cond231:yhr031c\n mSPR28:Septin-related protein expressed during sporulation,,Null mu\ntant is viable\n mYNL033W:Unknown ,, Unknown\n Cond934:8h\n Cond920:3h\n mBNR1:Bni1p-related protein, helps regulate reorganization of the \nactin cytoskeleton, potential target of Rho4p,,Null mutant i\ns viable; bni1 bnr1 double mutant exhibits severe temperatur\ne sensitive growth\n Cond961:t7_g/r_ratio\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mYOR298W:Unknown ,, Unknown\n Cond935:10h\n Cond449:glucose_vs._reference_pool_car-1\n mYHR054C:Unknown ,, Unknown\n mTEP1:Similar to human tumor suppressor gene known as TEP1, MMAC1 \nand PTEN1,tyrosine phosphatase (putative),\n mMSH4:dispensable for DNA repair, required for full levels of reci\nprocal exchange and spore viability,meiosis specific protein\n, E.coli MutS protein, localizes to discrete sites on meioti\nc chromosomes,Null mutant is viable, has no apparent defect \nin mismatch repair, wild-type levels of gene conversion and \npostmeiotic segregation\n mYJL045W:Unknown ,, Unknown\n Cond87:isw1\n Cond936:12h\n Cond871:yhe710-ss\n mYOR255W:Unknown ,, Unknown\n Cond88:isw1,isw2\n Cond625:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y12-121\n Cond918:1h\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYGL015C:Unknown ,, Unknown\n Cond422:YPD_stationary_phase_2_h_ypd-1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond963:t11.5_g/r_ratio\n mYAL018C:Unknown ,, Unknown\n mSTE3:The a factor receptor encoded by the STE3 gene allows yeast \ncells of the Alpha mating type to recognize cells of the a m\nating type,a-factor receptor,The null mutant is viable. Alph\na cells lacking STE3 are sterile, but a cells lacking STE3 c\nan mate.\n mGIP1:Glc7-interacting protein.,,sporulation defective\n mYOL024W:Unknown ,, Unknown\n mYKL177W:Unknown ,, Unknown\n mCDA1:Required for proper formation of the ascospore wall,chitin d\neacetylase,Null mutant is viable, mutants spores disrupted f\nor both cda1 and cda2 fail to emit natural fluorescence and \nare sensitive to hydrolyrtic enzymes, ether, and heat shock\n mYOR365C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYCL048W:Unknown ,, Unknown\n mYDR317W:Unknown ,, Unknown\n mYOL162W:Unknown ,, Unknown\n mSPO16:Early meiotic protein required for efficient spore formation\n,,sporulation defective\n mYHL012W:Unknown ,, Unknown\n mSSP1:Involved in the control of meiotic nuclear divisions & spore\n formation; dispensable for mitosis, premeiotic DNA synthesi\ns, recombination, meiosis I, meiosis II, & initiation of pro\nspore walls; required for spore wall elongation,,Null mutant\n is viable; spo3-1 at a semi-permissive temperature produces\n asci with one or two randomly packaged haploid spores; at a\n restrictive temperature, prospore walls grow and close prio\nr to the completion of meiosis II, resulting in immature ane\nuploid and/or anucleate spores. Multinucleate cells completi\nng meiosis II, but blocked in spore development, bud and res\nume division in return to growth assay.\n mDAL1:allantoinase,allantoinase,Allantoin degradation deficient\n mYSW1:Spore-specific protein,,\n mHOP1:Meiosis-specific protein involved in homologous chromosome s\nynapsis and chiasmata formation,DNA binding protein,decrease\nd levels of meiotic crossing over and intragenic recombinati\non between markers on homologous chromosomes\n mYBR250W:Unknown ,, Unknown\n mSPS18:sporulation-specific protein,transcription factor,suppressio\nn of X-ray sensitivity of rad55\n mMIP6:RNA-binding protein, interacts with MEX67,,\n mYGL230C:Unknown ,, Unknown\n Cond960:t5_g/r_ratio\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n mHXT14:High-affinity hexose transporter,hexose transporter,\n Cond938:2h\n Cond964:ndt80_delete_early_g/r_ratio\n mYGR226C:Unknown ,, Unknown\n Cond962:t9_g/r_ratio\n mYFL040W:Unknown ,, Unknown\n mSPO20:DBF2 Interacting Protein; SNAP 25 homolog,DBF2 interacting p\nrotein , SNAP 25 homolog,Null mutant is viable, other mutant\n fails to form spores\n mYDR042C:Unknown ,, Unknown\n mSPO21:sporulation defective,,meiosis proficient, fails to form spo\nres\n mSPR1:Sporulation regulated genes,exo-1,3-beta-glucanase, sporulat\nion-specific,Fail to hydrolyze p-nitrophenyl-beta-D-glucanas\ne or laminarin; mutant spores exhibit reduced thermoresistan\nce\n mSPR28 mSPR3
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Computational Genomics Lab, Tel-Aviv uniresity