Module number 3222




Database revision : gnsdb28.10
Date : Tue Feb 25 17:14:19 2003
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Cond547:cln3-1\n Cond498:wtħ500nMaF,30minlog10(intensity)\n Cond755: Cond494:wtħ5nMaF,30minlog10(intensity)\n Cond565:alpha98\n Cond798:Ca30'\n Cond548:cln3-2\n Cond552:alpha7\n Cond500:wtħ50nMaF,15minlog10(intensity)\n Cond751: Cond13:ase1(**12)\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond533:fus3D+50nMaF/wt+50nMaF,30minlog10(intensity)\n Cond735: Cond504:wtħ50nMaF,90minlog10(intensity)\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n Cond556:alpha35\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond519:rst1Drst2Dħ50nMaF,30minlog10(intensity)\n Cond745: mYCR064C:Unknown ,, Unknown\n Cond505:wtħ50nMaF,120minlog10(intensity)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n mGAS1:Glycophospholipid-anchored surface protein,cell surface glyc\noprotein 115-120 kDa,Null mutant is slow growing and exhibit\ns cell wall defects.\n Cond53:erg2\n Cond507:bni1Dħ50nMaF,90minlog10(intensity)\n Cond509:kss1Dħ50nMaF,30minlog10(intensity)\n Cond496:wtħ50nMaF,30minlog10(intensity)\n mCLN1:role in cell cycle START,G1 cyclin,Null mutant is viable, ex\nhibits G1 arrest\n Cond748: COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n mCIS3:cik1 suppressor,similar to Hsp150p and Pir1p, Pir2p, and Pir\n3p,Null mutant is viable; CIS3 is a high copy suppressor of \ncik1 deletion mutants\n Cond480:WT+/-100mM3AT(SetA)(R491)\n mCWP2:major constituent of the cell wall containing GPI-anchor, pl\nays a role in stabilizing the cell wall, low pH resistance p\nrotein,cell wall mannoprotein,Null mutant is viable, display\ns increased sensitivity to Congo red, calcofluor white, and \nZymolyase\n mYMR144W:Unknown ,, Unknown\n Cond566:alpha105\n mCSI2:chitin synthase involved,chitin synthase 3 complex structura\nl component (putative),Null mutant is viable but shows deloc\nalized chitin deposition\n Cond495:wtħ15.8nMaF,30minlog10(intensity)\n Cond279:ERG11(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond752: Cond508:bni1Dħ50nMaF,120minlog10(intensity)\n mYHP1:Hypothetical ORF,,\n Cond557:alpha42\n mHHT2:Histone H3 (HHT1 and HHT2 code for identical proteins),histo\nne H3 (HHT1 and HHT2 code for identical proteins),\n Cond807:crz1/Ca30'\n Cond506:bni1Dħ50nMaF,60minlog10(intensity)\n Cond580:cdc15_150\n mYKL097C:Unknown ,, Unknown\n Cond502:wtħ50nMaF,45minlog10(intensity)\n mSPC98:Involved in microtubule organization by the SBP,spindle pole\n body component,Null mutant is inviable; overexpression is t\noxic resulting in accumulation of cells with large buds, 2N \nDNA content, defect in microtubule structure. ts-phenotype: \narrest in G2 of cell cycle with large bud, duplicated spindl\ne pole bodies, short spindle and elongated cytoplasmic micro\ntubules\n Cond581:cdc15_160\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond563:alpha84\n mELO1:elongation enzyme 1, required for the elongation of the satu\nrated fatty acid tetradecanoic acid (14:0) to that of hexade\ncanoic acid (16:0),,Null mutant is viable, but shows no grow\nth on media supplemented with less than 16-C saturated fatty\n acid in a fatty acid synthase minus background\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond175:swi4\n Cond806:crz1/Ca15'\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cond501:wt+/-50nMaF,30minlog10(intensity)\n Cond250:ymr031w-a\n mHTA1:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable\n mHTA2:Histone H2A (HTA1 and HTA2 code for nearly identical protein\ns),histone H2A (HTA1 and HTA2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2. Overexpression of TRT2 can s\nuppress Ty insertion mutations\n Cond153:sgs1\n mHCM1:Dosage-dependent suppressor of cmd1-1 mutation; shows homolo\ngy to fork head family of DNA-binding proteins,,Null mutant \nis viable; exacerbates temperature-sensitivity of a cmd1-1 (\ncalmodulin) mutant\n Cond738:90\n mHHF1:Histone H4 (HHF1 and HHF2 code for identical proteins),histo\nne H4 (HHF1 and HHF2 code for identical proteins),\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond294:Itraconazole\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mTOS11:Hypothetical ORF,,\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond742: Cond747: Calcin.crz1:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond497:wtħ158nMaF,30minlog10(intensity)\n Cond560:alpha63\n Cond576:cdc15_110\n Cond555:alpha28\n Cond493:wtħ1.5nMaF,30minlog10(intensity)\n mYOR246C:Unknown ,, Unknown\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n Cond736: Cond511:GAL-STE4,3hrs.gallog10(intensity)\n Cond503:wtħ50nMaF,60minlog10(intensity)\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond564:alpha91\n mSNA2:Unknown ,, Unknown\n mSRL1:Suppressor of rad53 lethality,,\n Cond521:fus3-K42Dħ50nMaF,30minlog10(intensity)\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n mHTB1:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable\n Cond551:alpha0\n mHTB2:Histone H2B (HTB1 and HTB2 code for nearly identical protein\ns),histone H2B (HTB1 and HTB2 code for nearly identical prot\neins),Null mutant is viable. Deletion of the HTA2-HTB2 (TRT2\n) locus has no reported observable phenotypes, presumably be\ncause HTA1-HTB1 (TRT1) expression is upregulated and can com\npensate in the absence of TRT2\n Cond652:wt_plus_gamma_20_min\n mHHF1 mHTA1 mHHT2 mHTB1
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Computational Genomics Lab, Tel-Aviv uniresity