Module number 3179




Database revision : gnsdb28.10
Date : Tue Feb 25 17:18:28 2003
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mYNL319W:Unknown ,, Unknown\n mYPL103C:Unknown ,, Unknown\n mTKL1:Transketolase 1,transketolase 1,Null mutant is viable; growt\nh on fermentable carbon sources, but not gluconeogenic carbo\nn sources, is reduced; tkl1 tkl2 mutants are auxotrophic for\n aromatic amino acids\n mSHS1:Interacts with Spa2p and plays a role in cytokinesis,,defici\nent for cytokinesis\n mYPR076W:Unknown ,, Unknown\n mHMS2:High-copy mep2 suppressor,heat shock transcription factor ho\nmolog,Null mutant is viable; multicopy expression suppresses\n the pseudohyphal defect of mep2/mep2 strains\n mHYR1:Hydroperoxide resistance conferring gene,glutathione-peroxid\nase (putative),Null mutant is hypersensitive to oxidative st\nress\n mYMR158W-A:Unknown ,, Unknown\n mAPM4:Clathrin associated protein, medium subunit,clathrin associa\nted protein complex medium subunit,\n mINP54:INositol polyphosphate 5-Phosphatase, fourth one identified;\n has homology to Type I mammalian inositol polyphosphate 5-p\nhosphatases,inositol polyphosphate 5-phosphatase,\n mBEM3:Gtpase-activating protein activity toward the essential bud-\nsite assembly GTPase Cdc42,rho GTPase activating protein (GA\nP),Null mutant is viable.\n mYER156C:Unknown ,, Unknown\n mCLB2:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb1 mutation)\n mSTV1:Stv1p and Vph1p may be equivalent subunits for vacuolar-type\n H(+)-ATPases located on different organelles,110 kDa subuni\nt; not in vacuole membrane , vacuolar H-ATPase,Null mutant i\ns viable, displays additive phenotypes in combination with v\nph1 null mutations\n mMPH1:Mutator PHenotype; Similar to ATP-dependent RNA helicases,,\n mYGR223C:Unknown ,, Unknown\n mPTM1:Putative membrane protein,membrane protein (putative),Null m\nutant is viable, no observable phenotype\n mMDM1:Intermediate filament protein involved in organelle inherita\nnce,intermediate filament protein,Null mutant is inviable; t\nemperature sensitive mutants display defective transfer of n\nuclei and mitochondria into developing buds at the non-permi\nssive temperature\n mYNL127W:Unknown ,, Unknown\n mWWM1:Unknown ,, Unknown\n mYGR012W:Unknown ,, Unknown\n mTOP1:topoisomerase I,topoisomerase I,Null mutant is viable\n mUBR1:Ubiquitin-protein ligase,ubiquitin-protein ligase,Null mutan\nt is viable, unable to degrade substrates of the N-end rule \npathway, partially defective in sporulation\n mYPL034W:Unknown ,, Unknown\n mYJR098C:Unknown ,, Unknown\n mPEX14:Peroxisomal peripheral membrane protein (peroxin) involved i\nn import of peroxisomal matrix proteins,,Null mutant is viab\nle but is unable to grow on oleate and lacks peroxisomes\n mYFL034W:Unknown ,, Unknown\n mYBL089W:Unknown ,, Unknown\n mZRC1:Zinc- and cadmium-resistance protein,,Null mutant is viable \nand sensitive to zinc\n mMF(ALPHA)2:alpha mating factor,alpha mating factor,Null mutant is viabl\ne.\n mUBC8:Ubiquitin-conjugating enzyme that is able to ubiquitinate hi\nstones in vitro,ubiquitin-conjugating enzyme , ubiquitin-pro\ntein ligase,Null mutant is viable\n mBPH1:beige protein homologue 1,,Null mutant is viable, sensitive \nto low pH\n mFMT1:Formyl-Methionyl-tRNA Transformylase (consistent with name o\nf bacterial homologs),methionyl-tRNA transformylase,Null mut\nant is viable and lacks mitochondrial formyl-Met-tRNA\n mYPL136W:Unknown ,, Unknown\n mYBL010C:Unknown ,, Unknown\n mYIR003W:Unknown ,, Unknown\n mJNM1:coiled-coil domain protein required for proper nuclear migra\ntion during mitosis (but not during conjugation),,Null mutan\nt is viable but is cold-sensitive\n mSTD1:interacts with the SNF1 protein kinase and TBP in two-hybrid\n and in in vitro binding studies,MTH1 homolog,Null mutant is\n viable, no defects in mating or sporulation. Suppressor of \nTBP deletion; multicopy suppressor of SNF; std1-mth1 has def\nective glucose derepression and sporulation\n mRTF1:Directly or indirectly regulates the DNA-binding properties \nof Spt15p, the TATA box-binding protein, and the relative ac\ntivities of different TATA elements,nuclear protein,Null mut\nant is viable and can suppress TATA box-binding protein muta\nnts (SPT15) in an allele-specific fashion\n mARL1:Hydrolyzes GTP; myristylated; in soluble fraction,ADP-ribosy\nlation factor-like protein 1,Null mutant is viable\n mYGL235W:Unknown ,, Unknown\n mYUH1:ubiquitin hydrolase,ubiquitin hydrolase,\n mDPH5:diphthamide biosynthesis,,Null mutant is viable\n mZRG8:Zinc regulated gene,,\n mYMR221C:Unknown ,, Unknown\n mRMS1:Transcription regulator,,null mutant is viable with no appar\nent defects\n mZRG17:zinc-regulated gene,,\n mYGL152C:Unknown ,, Unknown\n mVPS13:vacuolar Protein Sorting,,Null mutant is viable but exhibits\n defects in vacuolar protein sorting.\n mCDC50:cell division cycle mutant,,Null mutant is cold-sensitive an\nd sensitive to MMS and HU\n mYMR029C:Unknown ,, Unknown\n mGIS2:GIG3 suppressor,,\n mRHO2:Gtp-binding protein of the rho subfamily of ras-like protein\ns,GTP-binding protein , rho subfamily,null is viable\n mSYT1:Suppressor of Ypt3,,\n mPEX6:Required for peroxisome assembly,AAA ATPase,lack of peroxiso\nme biogenesis\n mYLR224W:Unknown ,, Unknown\n mENT5:Unknown ,, Unknown\n mYNR040W:Unknown ,, Unknown\n mYPR053C:Unknown ,, Unknown\n mSUB1:Suppressor of TFIIB mutations,transcriptional coactivator,Nu\nll mutant is viable, auxotrophic for inositol; high copy sup\npressor of SUA7 (TFIIB) mutations. Overexpression of SUB1 st\nimulates transcription by some types of activators in vivo\n mYBR071W:Unknown ,, Unknown\n mGCV2:Glycine CleaVage system,glycine cleavage system P subunit , \nglycine decarboxylase complex P subunit , glycine synthase P\n subunit,Inability to convert glycine to serine (ser1 backgr\nound); Inability to utilize glycine as a nitogen source.\n mANB1:hypusine containg protein; ANB1 is expressed under anaerobic\n conditions and repressed under aerobic conditions whereas i\nts homolog HYP2 is inversely regulated,translation initiatio\nn factor eIF-5A, anaerobically expressed form,null mutant is\n viable; a double mutant containing disruptions of both ANB1\n and and the highly homologous HYP2 is inviable\n mNTO1:Unknown ,, Unknown\n mYBR235W:Unknown ,, Unknown\n mIMD3:Hypothetical ORF,IMP dehydrogenase homolog,\n mRPL15B:Homology to rat L15,ribosomal protein L15B (YL10) (L13B) (rp\n15R),\n mYOL003C:Unknown ,, Unknown\n mAPS1:Involved in a subset of clathrin functions at the Golgi,clat\nhrin associated protein complex small subunit,Null mutant is\n viable; aps1 mutants demonstrate synthetic effects with chc\n1 alleles\n mYNL136W:Unknown ,, Unknown\n mSWD3:YBR175W,,\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYNL122C:Unknown ,, Unknown\n mPIB1:Phosphatidylinositol(3)-phosphate binding,,none yet known\n mNUT1:Negative regulator of URS2 of the HO promoter,,Null mutant i\ns viable, deletion of NUT1 causes a constitutive, Swi4p-inde\npendent phenotype in combination with the nut2-1 allele or a\nn allele of CCR4\n mURK1:converts ATP and uridine to ADP and UMP,uridine kinase,\n mSED1:putative cell surface glycoprotein,cell surface glycoprotein\n (putative),Null mutant is viable; during stationary phase, \nnull mutants exhibit increased sensitivity to Zymolyase.\n mYPT7:Gtp-binding protein of the rab family; required for homotypi\nc fusion event in vacuole inheritance, for endosome-endosome\n fusion, and for fusion of endosomes to vacuoles when expres\nsed from high copy plasmid,GTP-binding protein , rab family \n, GTP-binding protein , rab family,Null mutant is viable, ch\naracterized by highly fragmented vacuoles and differential d\nefects of vacuolar transport and maturation\n mSCJ1:dnaJ homolog,DnaJ homolog,Null mutant is viable but exhibits\n defects in protein sorting and sensitivity to tunicamycin.\n mGCS1:Zn-finger-containing protein that functions as ADP-ribosylat\nion factor GTPase-activating protein and is involved in regu\nlating vesicle transport,ADP-ribosylation factor GTPase-acti\nvating protein (ARF GAP),Null mutant is cold-sensitive for r\neentry into mitotic cell cycle from stationary phase and sho\nws inefficient secretion of invertase\n mAPG12:autophagy,,Null mutant is viable, defective in autophagy\n mYBL012C:Unknown ,, Unknown\n mAPG13:autophagy,,Defective in autophagy\n mSHR5:Involved in RAS localization and palmitoylation,,Null mutant\n is viable; exhibits normal palmityltransferase activity in \nvitro and attenuates Ras function in cells with mutant Ras2 \nproteins that are not farnesylated or palmitoylated; shr5 mu\ntation originally isolated as suppressor of Ras function\n mAPL3:clathrin Associated Protein complex Large subunit,clathrin a\nssociated protein complex large subunit,Null mutant is viabl\ne\n mFUN21:Function unknown now,,Null mutant is viable\n mAPL4:Gamma-adaptin, large subunit of the clathrin-associated prot\nein (AP) complex,clathrin associated protein complex large s\nubunit , gamma-adaptin,\n mTEF4:Translation elongation factor EF-1gamma,translation elongati\non factor EF-1gamma,\n mAPG16:autophagy,,Null mutant is viable, defective in autophagy\n mYGR243W:Unknown ,, Unknown\n mHVG1:Homologous to VRG4,nucleotide sugar transporter (putative),N\null mutant is viable\n mYGL226W:Unknown ,, Unknown\n mYDR466W:Unknown ,, Unknown\n mDSE3:Hypothetical ORF,,\n mYGL262W:Unknown ,, Unknown\n mFYV14:Function required for Yeast Viability on toxin exposure,,Nul\nl mutant is viable but exhibits K1 killer toxin hypersensiti\nvity.\n mYJL192C:Unknown ,, Unknown\n mELA1:similar to mammalian elongin A, interacts with elongin C,elo\nngin A transcription elongation factor,viable\n mSNA2:Unknown ,, Unknown\n mYBR062C:Unknown ,, Unknown\n mYPL182C:Unknown ,, Unknown\n mYOR053W:Unknown ,, Unknown\n mPPH22:serine-threonine protein phosphatase 2A,,Null mutant is viab\nle, pph21 pph22 mutants produce very small spores in some st\nrain backgrounds and are inviable in others, pph21 pph22 pph\n3 mutants are inviable\n mSWE1:protein kinase homolog,protein kinase homolog,Null mutant is\n viable\n mTRS33:Trapp subunit of 33 kDa,,Null mutant is viable\n mSGN1:contains one RNA recognition (RRM) domain,,\n mYDL050C:Unknown ,, Unknown\n mNHP6A:Homologous to mammalian high mobility group proteins 1 and 2\n; functions redundantly with the highly homologous gene, NHP\n6A; high-mobility group non-histone chromatin protein,11 kDa\n nonhistone chromosomal protein,Deleting both NHP6A and NHP6\nB gives temperature-sensitive yeast with morphological and c\nytoskeletal defects at the restrictive temperature defects a\nre suppressed by 1 M sorbitol in the medium; nhp6a nhp6b dou\nble mutant also lacks induction of a subset of genes\n mAPG12 mAPG16 mFYV14 mIMD3 mELA1 mSWE1 mCLB2
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity