Module number 3105




Database revision : gnsdb28.10
Date : Tue Feb 25 17:06:09 2003
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mYNL319W:Unknown ,, Unknown\n mRAD28:Protein involved in the same pathway as Rad26p, has beta-tra\nnsducin (WD-40) repeats,,Null mutant is viable but is hyperm\nutable following exposure to UV light and is slightly more s\nensitive to UV light in the presence of mutations in rad7 or\n rad16\n mAPG5:Involved in autophagy,,reduced viability upon nutrient starv\nation; defective in autophagy\n mVPS74:Unknown ,, Unknown\n mAPG7:autophagy,,Null mutant is viable, defective in autophagy\n mGLT1:Glutamate synthase (NADH),glutamate synthase (NADH),Null mut\nant is viable\n mENT5:Unknown ,, Unknown\n mUGA3:Transcriptional activator necessary for gamma-aminobutyrate \n(GABA)-dependent induction of GABA genes (such as UGA1, UGA2\n, UGA4),zinc finger transcription factor of the Zn(2)-Cys(6)\n binuclear cluster domain type,Null mutant is viable but exh\nibits defects in activation of UGA1 and UGA4.\n mYMR258C:Unknown ,, Unknown\n mYDR031W:Unknown ,, Unknown\n mATX1:antioxidant protein and metal homeostasis factor, protects a\ngainst oxygen toxicity,copper binding homeostasis protein (p\nutative),hypersensitive toward paraquat (a generator of supe\nroxide anion)\n mFET3:FET3 encodes a ferro-O2-oxidoreductase that is part of the h\nigh-affinity iron transport system,multicopper oxidase,The n\null mutant is viable but defective for high affinity Fe(II) \nuptake. The null mutant is inviable when environmental iron \nis limiting.\n mANB1:hypusine containg protein; ANB1 is expressed under anaerobic\n conditions and repressed under aerobic conditions whereas i\nts homolog HYP2 is inversely regulated,translation initiatio\nn factor eIF-5A, anaerobically expressed form,null mutant is\n viable; a double mutant containing disruptions of both ANB1\n and and the highly homologous HYP2 is inviable\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n mSFH5:Unknown ,, Unknown\n mHNT3:Unknown ,, Unknown\n mCLB3:Involved in mitotic induction and perhaps in DNA replication\n and spindle assembly,B-type cyclin,Null mutant is viable\n mPTM1:Putative membrane protein,membrane protein (putative),Null m\nutant is viable, no observable phenotype\n mYBR027C:Unknown ,, Unknown\n mPES4:Suppressor of DNA polymerase epsilon mutation,poly(A) bindin\ng protein , similar to YHR015W,\n mYBR216C:Unknown ,, Unknown\n mYNL122C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYMR126C:Unknown ,, Unknown\n mYJR054W:Unknown ,, Unknown\n mVPS27:hydrophilic protein; has cysteine rich putative zinc finger \nesential for function,cysteine rich putative zinc finger ess\nential for function , hydrophilic protein , cysteine rich pu\ntative zinc finger essential for function , hydrophilic prot\nein , cysteine rich putative zinc finger essential for funct\nion , hydrophilic protein , cysteine rich putative zinc fing\ner essential for function , hydrophilic protein , cysteine r\nich putative zinc finger essential for function , hydrophili\nc protein , cysteine rich putative zinc finger essential for\n function , hydrophilic protein,required for membrane traffi\nc to the vacuole\n mVPS29:vacuolar protein sorting,,Defective for sorting of soluble h\nydrolases to the vacuole. Mislocalisation of the vacuolar hy\ndrolase sorting receptor Vps10p.\n mITC1:Imitation switch Two Complex 1,,Null mutant is viable, but s\nhows abnormal morphology and reduced mating efficiency when \nthe disruption is in a MATalpha background. \n mYPR197C:Unknown ,, Unknown\n mYNL100W:Unknown ,, Unknown\n mEAF6:Unknown ,, Unknown\n mYJL207C:Unknown ,, Unknown\n mAUT1:Protein involved in autophagocytosis during starvation,,Null\n mutant is viable, defective in starvation-induced bulk flow\n transport of cytoplasmic proteins to the vacuole, exhibits \ndecreased survival rates during starvation, defective in pro\ntein degradation in the vacuoles induced by nitrogen starvat\nion, homozygous diploids fail to sporulate\n mAPG12:autophagy,,Null mutant is viable, defective in autophagy\n mYBL012C:Unknown ,, Unknown\n mAPG13:autophagy,,Defective in autophagy\n mPHO13:p-nitrophenyl phosphatase,p-nitrophenyl phosphatase,Null mut\nant is viable\n mAPG16:autophagy,,Null mutant is viable, defective in autophagy\n mDPH2:Diptheria toxin resistance protein, required for diphthamide\n biosynthesis,,Null mutant is viable\n mSTB6:binds Sin3p in two-hybrid assay,,Null mutant is viable\n mIDP3:peroxisomal NADP-dependent isocitrate dehydrogenase,NADP-dep\nendent isocitrate dehydrogenase,Null mutant is viable but is\n unable to grow on polyunsaturated fatty acids as sole carbo\nn source\n mAUT7:Forms a protein complex with Aut2p to mediate attachment of \nautophagosomes to microtubules. Defective in maturation of t\nhe vacuolar protein, aminopeptidase I,similar to LC3, a micr\notubule-associated protein from rat,Null mutant is viable bu\nt lacks autophagocytosis and is unable to sporulate. AUT7 is\n a suppressor of mutant phenotypes of aut2-1 cells. Uptake o\nf precursor Aminopeptidase I into the vacuole depends on Aut\n2p and Aut7p.\n mDPH5:diphthamide biosynthesis,,Null mutant is viable\n mNFU1:Nifu-like protein,,Null mutant is viable on YPD 30 degrees C\n, and is synthetically lethal with SSQ1\n mYOR296W:Unknown ,, Unknown\n mELA1:similar to mammalian elongin A, interacts with elongin C,elo\nngin A transcription elongation factor,viable\n mSNA2:Unknown ,, Unknown\n mYER140W:Unknown ,, Unknown\n mCCC1:Functions in the homeostasis of both calcium and manganese i\nons,transmembrane Ca2+ transporter (putative),Wild-type comp\nlements csg1 (calcium sensitive-group) mutants when overexpr\nessed\n mARP1:actin-related protein of the dynactin complex,,Null mutant i\ns viable, but both null mutations and overexpression lead to\n defects in spindle orientation and nuclear migration\n mTRS33:Trapp subunit of 33 kDa,,Null mutant is viable\n mGIS2:GIG3 suppressor,,\n mYDL050C:Unknown ,, Unknown\n mAUT7 mAPG7 mAUT1 mAPG12 mFET3 mAPG16 mAPG5
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity