Module number 3061




Database revision : gnsdb28.10
Date : Tue Feb 25 17:12:33 2003
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mTLG1:member of the syntaxin family of t-SNAREs,tSNARE that affect\ns a late Golgi compartment,Endocytosis defect and loss of Ke\nx2p in SEY6210 background; Deletion may be lethal in some ge\nnetic backgrounds\n mPTC1:serine-threonine protein phosphatase,,Null mutant is viable;\n exhibits synthetic phenotypes in combination with ptp2, kcs\n1, and mpk1 (slt2) mutants; ptc1 mutations suppress the hype\nr-recombination of pkc1 mutants\n mYDL180W:Unknown ,, Unknown\n mATC1:interacts with AIP3, localized to the nucleus,,\n mYDR336W:Unknown ,, Unknown\n mYDL027C:Unknown ,, Unknown\n Cond136:rpl27a(**4)\n mARO10:Hypothetical ORF,,\n mPMP3:plasma membrane protein involved in salt tolerance,hypotheti\ncal transmembrane protein,Null mutant is viable and sensitiv\ne to cations such as sodium\n mENT5:Unknown ,, Unknown\n mYDR048C:Unknown ,, Unknown\n mUFD2:Ubiquitin fusion degradation protein,,Null mutant is viable \nbut exhibits increased sensitivity to ethanol stress.\n mYDR271C:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mRTT103:Regulator of Ty1 Transposition,,Gene disruption causes Ty1 h\nypertransposition phenotype\n mHNT1:Hint homolog, member of the histidine triad superfamily of n\nucleotide-binding proteins,,\n Cond679:DES460(wt)_vs._DES459(mec1)_genomic_DNA_comparison\n mCLB3:Involved in mitotic induction and perhaps in DNA replication\n and spindle assembly,B-type cyclin,Null mutant is viable\n mSTE5:Protein of the pheromone pathway,,Null mutant is viable but \nsterile. Overexpression of STE5 suppresses the temperature s\nensitivity of a cdc25 allele.\n mYDR179W-A:Unknown ,, Unknown\n mARO3:DAHP synthase; a.k.a. phospho-2-dehydro-3-deoxyheptonate ald\nolase, phenylalanine-inhibited; phospho-2-keto-3-deoxyhepton\nate aldolase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-\ndeoxy-D-arabine-heptulosonate-7-phosphate synthase,DAHP synt\nhase; a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, ph\nenylalanine-inhibited; phospho-2-keto-3-deoxyheptonate aldol\nase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-deoxy-D-a\nrabine-heptulosonate-7-phosphate synthase,null mutant is via\nble\n mYNL122C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSDC1:YDR469W,,\n Cond680:DES460(wt)_vs._DES459(mec1)_genomic_DNA_comparison_,\n2\n mPPH3:protein phosphatase type 2A,protein phosphatase type 2A,Null\n mutant is viable, pph3 pph21 pph22 mutants are inviable\n mYCK1:membrane-bound casein kinase I homolog,casein kinase I homol\nog,Null mutant is viable; yck1 yck2 double deletion mutants \nare inviable; yck1 point mutants suppress defective Snf1p ki\nnase activity in snf4 strains\n mYHL012W:Unknown ,, Unknown\n mNMD2:Protein involved in decay of mRNA containing nonsense codons\n,,Null mutant is viable, exhibits stabilization of nonsense-\ncontaining mRNAs\n mLSM6:Like Sm-F protein,snRNP protein,Null mutant is viable but gr\nows slowly at 23deg and 30deg, and is required for growth at\n 37deg\n mCSN9:Unknown ,, Unknown\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYDL091C:Unknown ,, Unknown\n mYDR370C:Unknown ,, Unknown\n Cond677:DES459_(mec1)_-_log_phase_(IR_time_=_0_sample)\n mYDR279W:Unknown ,, Unknown\n mSPL2:Suppressor of plc1-delta. Isolated as a dosage suppressor of\n the temperature-sensitive phenotype of a plc1 null mutant. \nAlso suppresses the hyperosmotic-sensitive phenotype of the \nplc1 null mutant.,,Null mutant is viable and shows no obviou\ns phenotype; spl2-delta plc1-delta double mutant fails to gr\now on SCD complete media, but grows on YPD at 25 degrees C\n mARO80:Hypothetical ORF,,\n mYDR267C:Unknown ,, Unknown\n mYDL110C:Unknown ,, Unknown\n mYDL177C:Unknown ,, Unknown\n mYDL133W:Unknown ,, Unknown\n mPPH21:serine-threonine protein phosphatase 2A,,Null mutant is viab\nle, pph21 pph22 mutants produce very small spores in some st\nrain backgrounds and are inviable in others, pph21 pph22 pph\n3 mutants are inviable\n mATP17:Subunit f of mitochondrial ATP synthase. Homologous to bovin\ne subunit f.,ATP synthase subunit f,No growth on glycerol\n mPPH22:serine-threonine protein phosphatase 2A,,Null mutant is viab\nle, pph21 pph22 mutants produce very small spores in some st\nrain backgrounds and are inviable in others, pph21 pph22 pph\n3 mutants are inviable\n mYPD1:Ypd1p is an intermediate protein between Sln1p and Ssk1p in \nthe phosphorelay reaction.,two-component phosphorelay interm\nediate,Null mutant is inviable due to the persistent activat\nion of HOG1 MAP kinase cascade. The ypd1 lethality can be su\nppressed by overexpression of the tyrosine phosphatase gene \nPTP2, or by inactivation of either one of SSK1, SSK2, PBS2, \nor HOG1 genes.\n mRGA2:contains a Rho-GAP domain and two LIM domains, similar to Rg\na1p and all known Rho-GAPs,Rho-GTPase Activating Protein,Nul\nl mutants are viable but increase the restrictive temperatur\ne of a cdc24-4 strain and increase the constitutive activati\non of the pheromone response pathway in conjungtion with mut\nations in RGA1 and BEM3; overexpression of RGA2 causes a dec\nrease in the restrictive temperature of a cdc42-1 strain\n mYDL203C:Unknown ,, Unknown\n mESBP6:Protein with similarity to mammalian monocarboxylate transpo\nrters MCT1 and MCT2,monocarboxylate permease (putative),\n mYDL073W:Unknown ,, Unknown\n mARR4:Unknown ,, Unknown\n mPPH21 mPPH22 mYCK1
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Computational Genomics Lab, Tel-Aviv uniresity