Module number 3047




Database revision : gnsdb28.10
Date : Tue Feb 25 17:08:49 2003
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mYJL015C:Unknown ,, Unknown\n Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n mGUT2:glycerol-3-phosphate dehydrogenase, mitochondrial,glycerol-3\n-phosphate dehydrogenase,Null mutant is viable, unable to ut\nilize glycerol as a carbon source\n mYJL218W:Unknown ,, Unknown\n mYPR015C:Unknown ,, Unknown\n Cond163:ssn6(haploid)\n mYMR107W:Unknown ,, Unknown\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n mTIR2:cold-shock induced protein of the Srp1p/Tip1p family of seri\nne-alanine-rich proteins,,Null mutant is viable.\n mTIR4:Hypothetical ORF,cell wall mannoprotein,inviable under anaer\nobic conditions\n mYKL161C:Unknown ,, Unknown\n mYBR230C:Unknown ,, Unknown\n mDIT2:Disp. for spores & spore viab. - required for dityrosine bio\nsynth. & dityrosine accumul. in outer spore wall (s.w.); s.w\n. matur. & resist. to ether & lytic enz. mRNA trans. mid/lat\ne during s.w. formation,catalyzes oxidation of N-formyl tyro\nsine to N,N-bisformyl dityrosine in vitro , cytochrome P450 \n56,lack outermost layer of spore wall\n mYER188W:Unknown ,, Unknown\n mYPR196W:Unknown ,, Unknown\n mFRE4:similar to FRE2,,\n mMNN4:involved in mannose metabolism,,mannan synthesis defective\n mYHR176W:Unknown ,, Unknown\n mPEX18:Peroxin; Pex18p and Pex21p are partially functionally redund\nant.,peroxin,Null mutant is viable but has reduced growth on\n oleate, partial impairment of peroxisome biogenesis\n mMPC54:Meiotic Plaque Component,,Null: viable. Other phenotypes: sp\norulation deficient.\n mSEF1:Suppressor of Essential Function,transcription factor (putat\nive),defective sporulation; high copy number suppressor of r\npm2\n mYHR213W:Unknown ,, Unknown\n mDAN1:Delayed Anaerobic,cell wall mannoprotein , induced during an\naerobic growth,Null mutant is viable\n mYCR101C:Unknown ,, Unknown\n mYLR311C:Unknown ,, Unknown\n mDAN3:delayed anaerobic gene,putative cell wall protein,unknown\n mYOR392W:Unknown ,, Unknown\n mGAL1:Haploid specific protein localized in the Golgi and plasma m\nembrane,galactokinase,Null mutant is viable and cannot utili\nze galactose.\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n mVEL1:Unknown ,, Unknown\n mICY1:Interacting with the cytoskeleton,,\n mYEL070W:Unknown ,, Unknown\n mSGA1:intracellular sporulation-specific glucoamylase involved in \nglycogen degradation. Induced during starvation of a/a late \nin sporulation, but dispensable for sporulation,glucoamylase\n,suppression of growth arrest of cdc25\n mYCL069W:Unknown ,, Unknown\n mRCK1:Serine/threonine protein kinase,,Null mutant is viable\n mYNR073C:Unknown ,, Unknown\n mYJR157W:Unknown ,, Unknown\n mAUS1:ABC(ATP-binding cassette) protein involved in Uptake of Ster\nols,ATP-binding cassette (ABC) family,Null mutant is viable \nbut exhibits reduced cholesterol accumulation.\n mSTP3:Involved in pre-tRNA splicing and in uptake of branched-chai\nn amino acids,,\n mDCI1:Delta(3,5)-delta(2,4)-dienoyl-CoA isomerase,delta(3,5)-delta\n(2,4)-dienoyl-CoA isomerase,\n mZAP1:Zinc-regulated DNA binding protein involved in zinc ion home\nostasis,metalloregulatory protein involved in zinc-responsiv\ne transcriptional regulation,High level expression of ZRT1 a\nnd ZRT2 in both zinc-limited and zinc-replete cells\n mODC1:Oxodicarboxylate carrier,mitochondrial 2-oxodicarboxylate tr\nansport protein,\n mPAU4:member of the seripauperin protein/gene family (see Gene_cla\nss PAU),,\n mPAU5:member of the seripauperin protein/gene family (see Gene_cla\nss PAU),,\n mHPA2:Histone and other Protein Acetyltransferase; Has sequence ho\nmology to known HATs and NATs,histone acetyltransferase,Null\n mutant is viable and does not show any detectable phenotype\n mPAU6:member of the seripauperin protein/gene family,,\n mYJL220W:Unknown ,, Unknown\n mGPG1:Unknown ,, Unknown\n mYOL159C:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSPS100:involved in spore development,sporulation-specific cell wall\n maturation protein,Null mutant is viable.\n mYIL024C:Unknown ,, Unknown\n mYGL146C:Unknown ,, Unknown\n mGIT1:permease involved in the uptake of glycerophosphoinositol (G\nroPIns),permease involved in the uptake of glycerophosphoino\nsitol (GroPIns),Null mutant is viable, exhibits decreased Gr\noPIns transport\n mYLR327C:Unknown ,, Unknown\n mLIN1:Unknown ,, Unknown\n mPRY1:Pathogen Related in Sc, contains homology to the plant PR-1 \nclass of pathogen related proteins. The protein sequence is \nover 60% identical with the Pry2p & Pry3p over 145 resid. PR\nY1 is >35% identical (50% similar) to tobacco PR-1c protein.\n,,\n Cond206:yel044w\n mKTR2:May be involved in extracellular matrix assembly; involved i\nn N-linked glycosylation of cell wall mannoproteins,mannosyl\ntransferase (putative) , type 2 membrane protein,Null mutant\n is viable, with partial resistance to killer toxin\n mAUT4:Autophagy gene essential for breakdown of autophagic vesicle\ns in the vacuole,,Null mutant is viable, but exhibits defect\ns in lysis of autophagic vesicles after delivery to the vacu\nole; vesicles accumulate in the vacuole in the absence of PM\nSF; maturation of the vacuolar protein, aminopeptidase I is \nunaffected in aut4\n mYLL055W:Unknown ,, Unknown\n mYIR041W:Unknown ,, Unknown\n mSPS18:sporulation-specific protein,transcription factor,suppressio\nn of X-ray sensitivity of rad55\n mYJL163C:Unknown ,, Unknown\n mYFR054C:Unknown ,, Unknown\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mYNL195C:Unknown ,, Unknown\n mYKL091C:Unknown ,, Unknown\n mGPH1:Releases glucose-1-phosphate from glycogen,glycogen phosphor\nylase,Null mutant is viable; haploid cells contain higher le\nvels of intracellular glycogen\n mTHI2:Transcriptional activator of thiamine biosynthetic genes,,Nu\nll mutant is viable, demonstrates thiamine auxotrophy, reduc\ned expression of thiamine biosynthetic genes\n mNRG1:involved in regulation of glucose repression,binds to UAS-1 \nin the STA1 promoter and can interact with Ssn6p , transcrip\ntional repressor,Null mutant is viable, relieves glucose rep\nression of SUC2 and STA1; suppresses snf mutations\n mYDR278C:Unknown ,, Unknown\n mTHI4:Protein highly expressed in early stationary phase during gr\nowth on molasses,biosynthetic pathway component producing th\ne thiazole precursor of thiamine,Null mutant is viable, auxo\ntrophic for thiamine\n mYSP3:subtilisin-like protease III,subtilisin-like protease III,\n mTHI7:Thiamine Metabolism,thiamine transporter,Null mutant is viab\nle, thi7 mutants are pyrithiamine resistant and cordycepin r\nesistant\n mRTA1:involved in 7-aminocholesterol resistance,,Null mutant is vi\nable; overexpression confers resistance to 7-aminocholestero\nl\n mYLL020C:Unknown ,, Unknown\n mKRE29:Killer toxin REsistant,,Heterozygous diploid mutant exhibits\n haploinsufficiency K1 killer toxin resistance\n mAQY1:Aquaporin,aquaporin,Null mutant is viable and exhibits impro\nved viability when grown under hypo-osmolar or hyper-osmolar\n stress.\n mSPG1:Hypothetical ORF,,Null mutant is viable; SPG1 is required fo\nr long-term survival in YPD at 37 degrees C.\n mTOS8:Hypothetical ORF,,\n mAQY2:aquaporin water channel in yeast,MIP family member , aquapor\nin (putative),\n mPXA2:Homolog of the human adrenoleukodystrophy transporter; forms\n a heterodimer with Pxa1p of two half ATP-binding cassette t\nransporters in the peroxisome membrane,ABC transporter 2,Nul\nl mutant is viable; reduces stability of Pxa1p\n mYAP6:bZIP protein,,\n mHMS1:High-copy mep2 suppressor,myc-family transcription factor ho\nmolog,Null mutant is viable; multicopy expression suppresses\n the pseudohyphal defect of mep2/mep2 strains\n mCTT1:cytoplasmic catalase T,catalase T,Null mutant is viable and \nheat sensitive\n mSMP1:Transcription factor of the MADS (Mcm1p, Agamous, Deficiens,\n SRF) box family; closely related to RLM1,,Null mutant is vi\nable; overexpression of DNA-binding domain of SMP1 causes an\n 'osmoremedial' phenotype\n mYOL015W:Unknown ,, Unknown\n mYOR192C:Unknown ,, Unknown\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n mYBL049W:Unknown ,, Unknown\n mMAL11:Part of MAL1 complex locus; encodes funct. maltose permease \nin all strains, exhibits sign. seq. variability; shows homol\n. to functional maltose permease from S. carlsbergenesis; me\nmber of the 12 tm domain superfamily of sugar transporters,a\nlpha-glucoside transporter , hexose transporter , maltose pe\nrmease,Mutant is defective in maltose fermentation.\n mMAL12:Part of the complex locus MAL1; functional in S288C,maltase,\nDefective maltose fermentation\n mYPR077C:Unknown ,, Unknown\n mYMR322C:Unknown ,, Unknown\n mSOR1:sorbitol-induced sorbitol dehydrogenase,sorbitol dehydrogena\nse, sorbitol-induced,\n mYKL223W:Unknown ,, Unknown\n mYFL052W:Unknown ,, Unknown\n mLEE1:Product of gene unknown,,\n mSPO73:Hypothetical ORF,,Undergoes meiotic nuclear divisions but do\nes not form spores\n mYJL216C:Unknown ,, Unknown\n mRCN1:Regulator of calcineurin,calcineurin inhibitor,Overexpressio\nn phenotype: decreased calcineurin function\n mYIR014W:Unknown ,, Unknown\n mYBR300C:Unknown ,, Unknown\n mTHI12:thiamine regulated gene, homologous to nmt1a in Schizosaccha\nromyces pombe; putatively involved in pyrimidine biosynthesi\ns,,\n mYER185W:Unknown ,, Unknown\n mOYE3:Old yellow enzyme,NADPH dehydrogenase,\n mPAI3:Cytoplasmic inhibitor of proteinase Pep4p,inhibitor of prote\ninase Pep4p,Null mutant is viable but shows increased rate o\nf protein degradation\n mYDL124W:Unknown ,, Unknown\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n mBAG7:Structural homolog of SAC7,GTPase activating protein (GAP),N\null mutant is viable; overexpression suppresses sac7 null mu\ntation\n mYJR037W:Unknown ,, Unknown\n mSTL1:sugar transporter-like protein,sugar transporter-like protei\nn,Null mutant is viable, no growth defects on galactose, man\nnose, maltose, or glycerol.\n mYBR285W:Unknown ,, Unknown\n Cond871:yhe710-ss\n mDAK2:dihydroxyacetone kinase,dihydroxyacetone kinase,Null mutant \nis viable and show no growth defect in normal medium; mutant\n lacking both dak1 and dak2 is sensitive to dihydroxyacetone\n during saline growth\n mYKL050C:Unknown ,, Unknown\n mYML131W:Unknown ,, Unknown\n mGLG1:self-glucosylating initiator of glycogen synthesis; similar \nto mammalian glycogenin,glycogen synthesis initiator,Null mu\ntant is viable; disruption of both GLG1 and GLG2 renders cel\nls unable to synthesize glycogen\n mYPR151C:Unknown ,, Unknown\n mYMR018W:Unknown ,, Unknown\n mOM45:45-kDa mitochondrial outer membrane protein,45 kDa mitochond\nrial outer membrane protein,Null mutant is viable and shows \nnormal growth, viability, mitochondrial function and mitocho\nndrial protein import\n mTHI20:THI for thiamine metabolism. Transcribed in the presence of \nlow level of thiamine (10-8M) and turned off in the presence\n of high level (10-6M) of thiamine. Under the positive contr\nol of THI2 and THI3.,,null mutant is viable; the double dele\ntion of YOL055c and YPL258c renders the cells auxotrophic fo\nr thiamine\n mYOL155C:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mTHI21:THI for thiamine metabolism. Transcribed in the presence of \nlow level of thiamine (10-8M) and turned off in the presence\n of high level (10-6M) of thiamine. Under the positive contr\nol of THI2 and THI3.,,null mutant is viable; the double dele\ntion of YOL055c and YPL258c renders the cells auxotrophic fo\nr thiamine\n mYHR022C:Unknown ,, Unknown\n mTHI22:THI for thiamine metabolism. Transcribed in the presence of \nlow level of thiamine (10-8M) and turned off in the presence\n of high level (10-6M) of thiamine. Under the positive contr\nol of THI2 and THI3.,,null mutant is viable\n mYGR043C:Unknown ,, Unknown\n mQDR1:Quinidine Resistance,multidrug resistance transporter,Null m\nutant is viable, but exhibits higher susceptibility to quini\ndine\n mSOL4:similar to SOL3,,\n mYAL065C:Unknown ,, Unknown\n mGRE2:induced by osmotic stress; similar to dihydroflavonol 4-redu\nctase from plants,,\n mMAL32:Part of the complex locus MAL3; functional in S288C; highly \nhomologous to MAL62 from S. carlsbergenesis strain CB11,malt\nase,Defective maltose fermentation\n Cond182:tup1(haploid)\n mBIO3:biotin biosynthesis,7,8-diamino-pelargonic acid aminotransfe\nrase (DAPA) aminotransferase,\n mPHO89:Probable Na+/Pi symporter,Na+/Pi symporter (putative),Null m\nutant is viable\n mBIO5:transmembrane regulator of KAPA/DAPA transport,transmembrane\n regulator of KAPA/DAPA transport,\n mNCA3:With NCA2, regulates proper expression of subunits 6 (Atp6p)\n and 8 (Atp8p ) of the Fo-F1 ATP synthase,,Null mutant is vi\nable\n mYDR070C:Unknown ,, Unknown\n mYLR004C:Unknown ,, Unknown\n mYKR105C:Unknown ,, Unknown\n Cond984:pho85D_DMSO_24_hrs._vs._F82G_10_mM_1-Na_PP1_24_hrs._\n mISF1:May regulate NAM7 function, possibly at level of mRNA turnov\ner,,Null mutant is viable; overexpression suppresses defects\n in hap2, hap3, and hap3 mutants; isf1 mbr1 double mutant ha\ns synthetic phenotypes\n mSHC1:sporulation-specific homolog of csd4,sporulation-specific pr\notein similar to Skt5p,\n mSIP18:Salt-Induced Protein,,Null mutant is viable.\n mYNL285W:Unknown ,, Unknown\n mACA1:contains an ATF/CREB-like bZIP domain; transcriptional activ\nator,basic leucine zipper (bZIP) transcription factor,\n mSUC2:invertase (sucrose hydrolyzing enzyme),invertase (sucrose hy\ndrolyzing enzyme),Null mutant is viable but cannot ferment s\nucrose\n mYMR251W:Unknown ,, Unknown\n mYPT53:Involved in vacuolar protein sorting and endocytosis,GTP-bin\nding protein , rab family,Null mutant is viable\n mHXT10:high-affinity hexose transporter,high affinity hexose transp\norter,\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n mYMR244W:Unknown ,, Unknown\n mYAR047C:Unknown ,, Unknown\n mHXT8:High-affinity hexose transporter,hexose permease,\n mHXT13:high-affinity hexose transporter,high affinity hexose transp\norter,\n mPFS1:Prospore Formation at Selected spindle poles,,Null mutant is\n viable; homozygous null diploid accumulates nonsister-spore\n dyads, normal meiotic spindles\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n mPHM8:involved in phosphate metabolism,,\n mYOR289W:Unknown ,, Unknown\n mHXT15:High-affinity hexose transporter,hexose transporter,\n mHXT16:hexose transporter,hexose permease,\n mHXT17:Hexose transporter,hexose transporter,\n mYGR226C:Unknown ,, Unknown\n mMBR1:Involved in mitochondrial biogenesis,,Null mutant is viable,\n shows defective growth on glycerol\n
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Computational Genomics Lab, Tel-Aviv uniresity