Module number 3007




Database revision : gnsdb28.10
Date : Tue Feb 25 17:03:00 2003
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Cond580:cdc15_150\n mHST3:Homolog of SIR2,,hst3 hst4 double mutant has defects in telo\nmeric silencing, cell cycle progression, radiation resistanc\ne, and genomic stability\n mIQG1:Homolog of the mammalian IQGAP1 and 2 genes; probable regula\ntor of cellular morphogenesis, inducing actin-ring formation\n in association with cytokinesis,,Null mutant is inviable (s\npores germinate, divide several times and lyse); cells are m\nultinucleate and have defects in cytokinesis, morphology, ac\ntin, and tubulin\n mPMP1:May regulate plasma membrane H(+)-ATPase,proteolipid associa\nted with plasma membrane H(+)-ATPase (Pma1p),Null mutant is \nviable; pmp1 pmp2 double mutant displays a lower Vmax for th\ne plasma membrane H(+)-ATPase (Pma1p)\n mPMA2:plasma membrane ATPase,plasma membrane ATPase,Null mutant is\n viable\n mCHS2:chitin synthase 2,chitin synthase 2,disruption results in lo\nss of well-defined septa and in growth arrest\n mYPL141C:Unknown ,, Unknown\n mSML1:Suppressor of mec lethality,,Null mutant is viable and suppr\nesses mec1 and rad53 lethality; suppresses mip1-1 at 37 C, s\nuppresses dun1 DNA damage sensitivity; increased resistance \nto DNA damage; increased dNTP pools\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond502:wtħ50nMaF,45minlog10(intensity)\n mFET3:FET3 encodes a ferro-O2-oxidoreductase that is part of the h\nigh-affinity iron transport system,multicopper oxidase,The n\null mutant is viable but defective for high affinity Fe(II) \nuptake. The null mutant is inviable when environmental iron \nis limiting.\n mBUD4:co-assembles with Bud3p at bud sites,,Null mutant is viable,\n haploids have dipolar budding, normally they have axial bud\nding, no effects on diploids\n Cond558:alpha49\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond585:cdc15_200\n mCLB2:Involved in mitotic induction,B-type cyclin,Null mutant is v\niable (lethal in combination with clb1 mutation)\n mYOR256C:Unknown ,, Unknown\n mPRM7:pheromone-regulated membrane protein,,\n Cond556:alpha35\n mMRH1:Membrane protein related to Hsp30p; Localized by immunofluor\nescence to membranes, mainly the plasma membr. punctuate imm\nunofluorescence pattern observed in buds. The nuclear envelo\npe, but not vacuole or mitochondrial membranes also stained,\n,Null mutant is viable\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond582:cdc15_170\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond573:cdc15_80\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Cond586:cdc15_210\n mTPO3:Unknown ,, Unknown\n Cond554:alpha21\n Cond571:cdc15_50\n Cond575:cdc15_100\n Cond974:WT_vs_F82G_2\n mNCE102:involved in secretion of proteins that lack classical secret\nory signal sequences,,An uncharacterized allele exhibits def\nects in the export of the mammalian protein galectin-1.\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n mYDL037C:Unknown ,, Unknown\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond587:cdc15_220\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond560:alpha63\n Cond576:cdc15_110\n Cond555:alpha28\n Cond568:alpha119\n Cond570:cdc15_30\n mNTA1:Removes amide group from N-terminal asparagine and glutamine\n, to generate aspartate and glutamate, which are destabilizi\nng terminal residues,52 kDa amidase specific for N-terminal \nasparagine and glutamine,Null mutant is viable but cannot de\ngrade N-end rule substrates that have N-terminal asparagine \nor glutamine\n mYBR190W:Unknown ,, Unknown\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mPHO3:Acid phosphatase, constitutive,acid phosphatase,phosphatase \ndeficient\n mYKR103W:Unknown ,, Unknown\n Cond559:alpha56\n mYRO2:Homolog to HSP30 heat shock protein Yro1p,,\n Cond553:alpha14\n Cond577:cdc15_120\n Cond550:clb2-1\n Cond567:alpha112\n mYNL057W:Unknown ,, Unknown\n Cond551:alpha0\n Cond549:clb2-2\n
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Computational Genomics Lab, Tel-Aviv uniresity