Module number 2915




Database revision : gnsdb28.10
Date : Tue Feb 25 17:33:03 2003
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UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond936:12h\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mERG12:mevalonate catabolism,mevalonate kinase,Null mutant is invia\nble and unable to grow vegetatively or germinate spores; mut\nants exhibit increased mitotic stability of plasmids with we\nak ARS elements.\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond944:SK1_ume6_YPA\n Cond879:MMC\n Cond767:Acid_40'\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond918:1h\n Y-Stre.NaCl:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond760:Heat_15'\n Cond887:t-BuOOH\n Cond765:Acid_10'\n mTIR2:cold-shock induced protein of the Srp1p/Tip1p family of seri\nne-alanine-rich proteins,,Null mutant is viable.\n mDSS4:dominant suppressor of sec4,GDP dissociation factor for Sec4\np,Null mutant is viable\n Cond875:60min\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond775:Alkali_80'\n Cond766:Acid_20'\n mAPS3:sigma3-like subunit of the yeast AP-3 complex which function\ns in transport of alkaline phosphatase to the vacuole via th\ne alternate pathway, suppressor of loss of casein kinase 1 f\nunction,,Null mutant is viable, rescues yck1,yck2 double mut\nant\n mOST2:Oligosaccharyltransferase catalyzes the transfer of oligosac\ncharide from dolichol-oligosaccharide donor to consensus gly\ncosylation acceptor sites (asparagines) in newly synthesized\n proteins in ER lumen,40% identical to vertebrate DAD1 prote\nin , oligosaccharyltransferase complex 16 kDa epsilon subuni\nt,Null mutant is inviable; overexpression of OST2 suppresses\n temperature-sensitivity of wbp1-2 mutant; conditional mutan\nts show pleiotropic underglycosylation of soluble and membra\nne-bound glycoproteins\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n mYPL107W:Unknown ,, Unknown\n Cond880:BCNU\n Cond776:Alkali_100'\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes.  Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond772:Alkali_20'\n mSPP41:appears to control expression of spliceosome components PRP4\n and PRP3,negative transcriptional regulator of prp spliceos\nome genes,Null mutant is inviable; suppressor of prp mutatio\nns\n Cond889:4NQO_2\n mSNF8:appears to be functionally related to SNF7,,Null mutant is v\niable, sporulation defective, grows poorly on raffinose as a\n carbon source, shows a five-fold decrease in invertase dere\npression\n mLTP1:Homologous to mammalian phosphotyrosine phosphatase,18 kDa p\nhosphotyrosine phosphatase,Null mutant is viable\n mYOR164C:Unknown ,, Unknown\n mCKB2:Casein kinase II, beta' subunit,Casein kinase II beta' subun\nit,Null mutant is viable\n Cond934:8h\n Cond771:Alkali_10'\n Cond789:NaCl_120'\n Cond773:Alkali_40'\n Cond938:2h\n Cond935:10h\n Cond768:Acid_60'\n Cond939:4h\n Cond790:Sorbitol_15'\n

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Computational Genomics Lab, Tel-Aviv uniresity