Module number 2863




Database revision : gnsdb28.10
Date : Tue Feb 25 17:36:24 2003
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mSPC2:subunit of signal peptidase complex, homologous to mammalian\n protein SPC25,signal peptidase complex subunit , similar to\n mammalian protein SPC25,Null mutant is viable. spc1 spc2 do\nuble deletion mutants grow relatively well as compared to wi\nld-type. spc2 sec11 double deletion mutant is inviable. Spc2\np is important for cell viability and signal peptidase activ\nity at high temperatures (42 degrees celsius).\n Cond717:t2-SSD1\n Cond720:t0+SSD1,H44\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond708:t0+SSD1\n Cond711:t2+Vec\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n mCUS2:cold sensitive U2 snRNA Supressor,,Null mutant is viable, en\nhances U2 mutations; mutations in this gene suppress the col\nd sensitive phenotype of U2 RNA mutation G53A\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns.  J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mYPL257W:Unknown ,, Unknown\n Cond906:(77i5)_S150-2B_YPD_NormInt\n mERV1:Protein essential for mitochondrial biogenesis and cell viab\nility,,Null mutant is inviable; mutants demonstrate defects \nin mitochondrial biogenesis\n mVMA22:Required for V-ATPase activity,,Null mutant is viable but is\n defective in vacuolar H(+)-ATPase activity, sensitive to ca\nlcium, cyclosporin A, and FK506, and requires calcineurin fo\nr viability\n Cond712:t4+SSD1\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n mMTF1:Mitochondrial RNA polymerase specificity factor,mitochondria\nl RNA polymerase specificity factor,Null mutant is viable, d\nefective in respiration, and lacks mtDNA.\n Cond723:t2-SSD1,M31\n mVPS29:vacuolar protein sorting,,Defective for sorting of soluble h\nydrolases to the vacuole. Mislocalisation of the vacuolar hy\ndrolase sorting receptor Vps10p.\n Cond719:t4-SSD1\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n mDPB3:C and C' subunits of DNA polymerase II,DNA polymerase II C a\nnd C' subunits,Null mutant is viable, shows increased sponta\nneous mutation rate\n Cond724:t4+SSD1,H44\n Cond715:t0-SSD1\n mTAF10:TFIID subunit (TBP-associated factor) with predicted molecul\nar weight of 23 kD.,TFIID subunit,Null mutant is inviable\n mMRPS28:Mitochondrial ribosomal protein MRPS28 (E. coli S15),ribosom\nal protein (E. coli S15),Null mutant is viable, unable to re\nspire, spontaneously loses portions of its mitochondrial gen\nomes at a high frequencY\n mSRB6:involved in transcription as part of Srb/Mediator complex,pa\nrt of Srb/Mediator complex , transcription factor,Null mutan\nt is inviable; temperature sensitive mutants are associated \nwith decreased total polyA+ RNA levels\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYJR087W:Unknown ,, Unknown\n mYOP1:Ypt Interacting Protein,,\n Cond718:t4+SSD1wt\n Cond721:t0-SSD1,M31\n Cond934:8h\n Cond659:DES460_(wt)_-_mock_irradiation_-_30_min\n mDCP1:Decapping protein involved in mRNA degradation,,Null mutant \nis inviable in the FY1679 background, but viable, though gro\nws slowly, in the CEN.PK141 background.\n mPNG1:de-N-glycosylation enzyme,peptide:N-glycanase,Null mutant is\n viable and shows no growth or viability defect under experi\nmental conditions\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Cond672:DES459_(mec1)_-_mock_irradiation_-_60_min\n Cond709:t0+Vec\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond710:t2+SSD1\n Cond59:erp4\n Cond660:DES460_(wt)_-_mock_irradiation_-_60_min\n

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Computational Genomics Lab, Tel-Aviv uniresity