Module number 2854




Database revision : gnsdb28.10
Date : Tue Feb 25 17:35:11 2003
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mYDL180W:Unknown ,, Unknown\n mATE1:arginyl-tRNA-protein transferase,arginyl-tRNA-protein transf\nerase,Null mutant is viable, but unable to degrade substrate\ns of the N-end rule pathway that start with residues recogni\nzed by the Arg-transferase\n mLOT6:LOw Temperature responsive,,\n mMDM30:Unknown ,, Unknown\n mYLR404W:Unknown ,, Unknown\n mYBL009W:Unknown ,, Unknown\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n mORM2:Unknown ,, Unknown\n Cond711:t2+Vec\n mURA4:Third step in pyrimidine biosynthesis pathway,dihydrooratase\n,Null mutant is viable and requires uracil\n mYSC83:similar to S. douglasii YSD83,,Null mutant is viable\n mDNM1:involved in receptor-mediated endocytosis and mitochondrial \norganization,similar to dynamin GTPase,Null mutant is viable\n, shows mating defects consistent with a delay in receptor-m\nediated endocytosis\n mBUD7:bud site selection,,Diploid-specific heterogenous bud site s\nelection\n mSTV1:Stv1p and Vph1p may be equivalent subunits for vacuolar-type\n H(+)-ATPases located on different organelles,110 kDa subuni\nt; not in vacuole membrane , vacuolar H-ATPase,Null mutant i\ns viable, displays additive phenotypes in combination with v\nph1 null mutations\n mMRPL38:mitochondrial ribosomal protein L14,ribosomal protein L14,\n mDAL82:Positive regulator of allophanate inducible genes,positive t\nranscriptional regulator,loss of induction for allantoin deg\nradation pathways\n mPGU1:Endo-polygalacturonase,endo-polygalacturonase,Null mutant is\n viable; exhibits clear halo around colonies on polygalactur\nonate medium\n mSSP120:secretory protein,,Null mutant is viable\n Cond724:t4+SSD1,H44\n Cond713:t4+Vec\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mFPS1:Suppressor of tps1/fdp1 and member of the MIP family of tran\nsmembrane channels; may be involved in glycerol efflux,glyce\nrol channel protein,Null mutant is viable\n mPNT1:Involved in targeting of proteins to the mitochondrial inner\n membrane; Pentamidine resistance protein,,Null mutant is vi\nable and shows slightly increased susceptibility to pentamid\nine (an anti-Pneumocystis carinii drug) and related compound\ns; confers resistance to pentamidine when present in high co\npy number\n Cond718:t4+SSD1wt\n mYNL026W:Unknown ,, Unknown\n mLEM3:Product of gene unknown,,null mutant is sensitive to brefeld\nin A and shows increased glucocorticoid receptor activity in\n response to dexamethasone\n Cond709:t0+Vec\n mIES5:Ino Eighty Subunit 5,,Null: non essential.\n mYKR016W:Unknown ,, Unknown\n mNUP53:Component of karyopherin docking complex of the nuclear pore\n complex,karyopherin docking complex component of the nuclea\nr pore complex,Null mutant is viable but disrupts Kap121 loc\nalization to the nuclear envelope.\n mBSD2:metal homeostasis protein; putative membrane protein,,Null m\nutant is viable; suppressor of oxygen toxicity in sod1 mutan\nts, increased sensitivity to copper and cadmium toxicity, el\nevation in copper ion accumulation\n mYLR224W:Unknown ,, Unknown\n mYLR064W:Unknown ,, Unknown\n mYLL029W:Unknown ,, Unknown\n Cond725:t4-SSD1,M31\n Cond708:t0+SSD1\n mNHA1:Putative Na+/H+ antiporter,,Null mutant is viable but shows \nincreased sensitivity to sodium and lithium; overexpression \nof NHA1 confers higher and partially Phenotype-dependent tol\nerance to those ions\n mYLR253W:Unknown ,, Unknown\n mSEC17:peripheral membrane protein required for vesicular transport\n between ER and Golgi,,secretion deficient\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond712:t4+SSD1\n mMTF1:Mitochondrial RNA polymerase specificity factor,mitochondria\nl RNA polymerase specificity factor,Null mutant is viable, d\nefective in respiration, and lacks mtDNA.\n mGRE2:induced by osmotic stress; similar to dihydroflavonol 4-redu\nctase from plants,,\n mPSR2:Plasma membrane Sodium Response 2,,Mutant is sensitive to so\ndium ions.\n mYDR128W:Unknown ,, Unknown\n Cond723:t2-SSD1,M31\n mRBK1:ribokinase,ribokinase,\n mECM19:ExtraCellular Mutant,,A Tn3 insertion into this gene causes \nhypersensitivity to the cell surface polymer perturbing agen\nt calcofluor white.\n mNGL1:DNase/RNase (putative); CCR4 C-terminal homolog, homology to\n drosophila Angel gene,DNase (putative) , RNase (putative),N\null mutant is viable.\n mYPL170W:Unknown ,, Unknown\n mSCJ1:dnaJ homolog,DnaJ homolog,Null mutant is viable but exhibits\n defects in protein sorting and sensitivity to tunicamycin.\n mYLR072W:Unknown ,, Unknown\n mUSA1:Identified by its interaction with the U1 snRNP-specific pro\ntein, Snp1p.,pre-mRNA splicing factor (putative),\n mMSB3:Multicopy Suppressor of Bud Emergence,GTPase activating prot\nein (GAP)  for Ypt6,Null mutant is viable. msb3/msb4 double \nmutant exhibits slow growth and disorganized actin cytoskele\nton\n Cond721:t0-SSD1,M31\n mPPA2:mitochondrial inorganic pyrophosphatase,inorganic pyrophosph\natase,Null mutant is viable but is unable to grow on respira\ntory carbon sources and lacks mitochondrial DNA\n mCUE1:Cue1p assembles with Ubc7p. Cue1p recruits Ubc7p to the cyto\nsolic surface of the endoplasmic reticulum. Assembly with Cu\ne1p is a prerequisite for the function of Ubc7p,Ubc7p bindin\ng and recruitment protein,Null mutant is viable and shows st\nabilization of ER degradation substrates\n mYLR345W:Unknown ,, Unknown\n mMMP1:S-MethylMethionine Permease,high affinity S-methylmethionine\n permease,Null mutant is viable but is unable to use S-methy\nlmethionine as a sulfur source\n mMAK32:Protein necessary for structural stability of L-A double-str\nanded RNA-containing particles,,\n mYLR454W:Unknown ,, Unknown\n mYKR007W:Unknown ,, Unknown\n mPTP1:phosphotyrosine-specific protein phosphatase,phosphotyrosine\n-specific protein phosphatase,viable\n Cond710:t2+SSD1\n mYBL095W:Unknown ,, Unknown\n Cond939:4h\n

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Computational Genomics Lab, Tel-Aviv uniresity