Module number 2800




Database revision : gnsdb28.10
Date : Tue Feb 25 17:28:03 2003
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Cond899:RPN4_MMS__\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast.  Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes.  Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond717:t2-SSD1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n Cond878:MNNG\n Cond895:G2MMS\n Cond47:ecm18(**7)\n mRPL7B:Homolog of mammalian ribosomal protein L7 and E. coli L30,ri\nbosomal protein L7B (L6B) (rp11) (YL8),Null mutant is viable\n; disruption of both RPL7A and RPL7B is lethal\n Cond879:MMC\n mYGL232W:Unknown ,, Unknown\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond882:zero3\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mURA5:Fifth step in pyrimidine biosynthesis pathway,orotate phosph\noribosyltransferase 1,Null mutant is viable\n Cond362:dtt_000_min__dtt-2\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n mMDM39:Unknown ,, Unknown\n Cond946:W303ume6_YPD\n Cond886:g-ray\n mERG2:sterol biosynthesis,C-8 sterol isomerase,Null mutant is viab\nle\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond892:S\n mYNL056W:Unknown ,, Unknown\n Cond745: Cond898:RPN4\n Cond463:29_deg_growth_ct-1\n Cond876:zero2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond890:G1\n mURM1:ubiquitin-like protein,ubiquitin-like protein,Null mutant is\n viable and has temperature-sensitive growth defect at 37 de\ngrees C\n mRNH70:RNase H(70), a 70 kDa ribonuclease H,ribonuclease H,Null mut\nant is viable.\n Cond872:Zero1\n Cond:\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond885:20\n Cond809:Na30'\n Cond942:SK1ume6_YPD\n Cond310:Heat_Shock_000_minutes_hs-2\n Cond55:erg4(haploid**7)\n mLYS12:homo-isocitrate dehydrogenase, an NAD-linked mitochondrial e\nnzyme required for the fourth step in the biosynthesis of ly\nsine, in which homo-isocitrate is oxidatively decarboxylated\n to alpha-ketoadipate.,homo-isocitrate dehydrogenase,Null mu\ntant is viable but shows decreased growth in the absence of \nlysine\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond881:4NQO\n mRPA34:RNA polymerase I subunit, not shared (A34.5),,Null mutant is\n viable but its RNA polymerase I lacks subunit A49 (rpa49p);\n synthetically lethal with RPA14; shows synthetic interactio\nns with DNA topoisomerase I (TPO1)\n Cond894:G2\n mCAF20:binds to eIF4E, the mRNA cap-binding protein, and represses \ncap-dependent translation initiation by interfering with the\n interaction of eIF4E and eIF4G,20 kDa subunit , mRNA cap bi\nnding protein eIF-4F , 20 kDa subunit , mRNA cap binding pro\ntein eIF-4F,Null mutant is viable and grows faster; deletion\n of CAF20 partially suppresses mutations in translation init\niation factors; overexpression of CAF20 causes slower growth\n and enhances translation mutation phenotypes\n mPFD1:Prefoldin subunit 1; putative homolog of subunit 1 of bovine\n prefoldin, a chaperone comprised of six subunits,bovine pre\nfoldin subunit 1 homolog (putative),\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n.  J Biol Chem. 2002 Aug 23;277(34):31079-88\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth.  Nature. 2000 Jul 6;406(6791):90-4.\n mSER2:phosphoserine phosphatase,phosphoserine phosphatase,serine-r\nequiring\n mTIM13:Translocase of the inner membrane; mitochondrial intermembra\nne space protein mediating import and insertion of polytopic\n inner membrane proteins,mitochondrial protein import machin\nery subunit,Null mutant is viable.\n

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Computational Genomics Lab, Tel-Aviv uniresity