Module number 2794




Database revision : gnsdb28.10
Date : Tue Feb 25 17:36:56 2003
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mMAF1:Mod5 protein sorting,,Mislocalizes Mod5p to the nucleus\n Cond899:RPN4_MMS__\n mMET13:putative methylenetetrahydrofolate reductase (mthfr),methyle\nnetetrahydrofolate reductase (mthfr) (putative),Null mutant \nis viable and shows methionine auxotrophy; double disruption\n of MET12 and MET13 (the two putative mthfr genes) also conf\ners methionine auxotrophy, but has no other known phenotype \nat this time.\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mPMA2:plasma membrane ATPase,plasma membrane ATPase,Null mutant is\n viable\n mYOR161C:Unknown ,, Unknown\n Cond777:msn2/4_acid_0'\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond887:t-BuOOH\n mARK1:actin regulating kinase,serine/threonine kinase (putative),N\null mutant is viable and shows slight delocalisation of acti\nn cytoskeleton\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mFET3:FET3 encodes a ferro-O2-oxidoreductase that is part of the h\nigh-affinity iron transport system,multicopper oxidase,The n\null mutant is viable but defective for high affinity Fe(II) \nuptake. The null mutant is inviable when environmental iron \nis limiting.\n mSTE13:dipeptidyl aminopeptidase,dipeptidyl aminopeptidase,Null mut\nant is viable, sporulation proficient\n mSYM1:Unknown ,, Unknown\n mBBC1:shows synthetic fitness defect with bni1 mutants and associa\ntes with the Bee1p-Vrp1p-Myo3/5p complex,,\n mYJL084C:Unknown ,, Unknown\n mMID2:Protein required for mating,,Null mutant is viable, dies whe\nn exposed to mating pheromone\n mNST1:Unknown ,, Unknown\n Y-Stre.msn2/4acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mYJL017W:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond883:5\n mOST3:Catalyzes the transfer of oligosaccharide from dolichol-olig\nosaccharide donor to consensus glycosylation acceptor sites \n(asparagines) in newly synth. proteins - ER lumen; may enhan\nce oligosacch. transfer to subset of acceptor substrates,oli\ngosaccharyl transferase glycoprotein complex 34 kDa gamma su\nbunit,Null mutant is viable but shows underglycosylation of \nsoluble and membrane-bound glycoproteins and contains less o\nligosaccharyltransferase activity in vitro\n mYNR061C:Unknown ,, Unknown\n Cond898:RPN4\n Cond28:cla4(haploid)\n mRAD50:coiled-coil protein, contains a purine-binding domain, two h\neptad repeats and a hydrophobic tail,Mre11-Rad50-Xrs2 protei\nn complex member involved in joining double-stranded breaks \nand DNA recombination,Null mutant is viable but defective fo\nr X-ray damage repair, sporulation, chromosome pairing, form\nation and processing of DS breaks, gene conversion and recip\nrocal recombination in non-rDNA, tripartite synaptonemal com\nplexes and heteroduplex DNA. Exhibits blocked meiotic recomb\nination and formation of synaptonemal complex at early stage\ns. rad50-1 or null is rescued by spo13 and rescues rad52 spo\n13.\n mSED1:putative cell surface glycoprotein,cell surface glycoprotein\n (putative),Null mutant is viable; during stationary phase, \nnull mutants exhibit increased sensitivity to Zymolyase.\n mSCW4:Soluble Cell Wall protein,soluble cell wall protein,Null mut\nant is viable.\n mHSP150:Heat shock protein, secretory glycoprotein,heat shock protei\nn , secretory glycoprotein , heat shock protein , secretory \nglycoprotein , heat shock protein , secretory glycoprotein,N\null mutant is viable\n mYHR140W:Unknown ,, Unknown\n mRCN1:Regulator of calcineurin,calcineurin inhibitor,Overexpressio\nn phenotype: decreased calcineurin function\n mYOR228C:Unknown ,, Unknown\n mESC1:Establishes Silent Chromatin,,\n mMAM3:Product of gene unknown,,\n Cond897:STATMMS\n mYNL320W:Unknown ,, Unknown\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mYHR054C:Unknown ,, Unknown\n Cond577:cdc15_120\n mKES1:Homologous to human oxysterol-binding protein; implicated in\n ergosterol biosynthesis and regulation of Golgi-derived tra\nnsport vesicle biogenesis,,Pleiotropic sterol-related phenot\nypes\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity