Module number 2719




Database revision : gnsdb28.10
Date : Tue Feb 25 17:26:44 2003
How to read this figure?


UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mKRE27:Killer toxin REsistant,,K1 killer toxin resistance\n Cond944:SK1_ume6_YPA\n mSPE3:biosynthesis of spermidine,putrescine aminopropyltransferase\n (spermidine synthase),Null mutant is viable, has no spermid\nine synthase activity, requires spermine or spermidine for g\nrowth\n mPMP3:plasma membrane protein involved in salt tolerance,hypotheti\ncal transmembrane protein,Null mutant is viable and sensitiv\ne to cations such as sodium\n Cond895:G2MMS\n mSML1:Suppressor of mec lethality,,Null mutant is viable and suppr\nesses mec1 and rad53 lethality; suppresses mip1-1 at 37 C, s\nuppresses dun1 DNA damage sensitivity; increased resistance \nto DNA damage; increased dNTP pools\n mERP4:Emp24p/Erv25p related protein 4,p24 protein involved in memb\nrane trafficking,viable\n Cond887:t-BuOOH\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond877:MMS\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mFET4:Putative transmembrane low-affinity Fe(II) transporter,low a\nffinity Fe2+ transport protein,Mutant lacks low affinity Fe(\nII) transport but has more active high affinity Fe(II) trans\nport activity\n Cond875:60min\n mPAU7:similar to Pau3, member of Pau1 family,,\n Cond972:anc1\n mERV14:ER-derived vesicles,14 kDa protein found on ER-derived vesic\nles,Null mutant is viable but exhibits defects in sporulatio\nn (diploids) and bud site selection (haploids). Null mutants\n also retain the bud site selection marker, Axl2p, in the ER\n and exhibit slow recovery from selective to rich media.\n mSEC53:involved in synthesis of GDP-mannose and dolichol-phosphate-\nmannose; required for protein assembly in endoplasmic reticu\nlum,phosphomannomutase,null is inviable; ts mutant is defect\nive in glycosylation, accumulating inactive and incompletely\n glycosylated forms of secretory proteins within the ER lume\nn\n Cond886:g-ray\n mERG2:sterol biosynthesis,C-8 sterol isomerase,Null mutant is viab\nle\n mYHL039W:Unknown ,, Unknown\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSYS1:Multicopy suppressor of ypt6 null mutation,,Null mutant is v\niable. sys1 ypt6 double mutant displays enhanced defects in \nvacuolar sorting and cell growth\n Cond883:5\n Cond319:37C_to_25C_shock_-_90_min\n mYIP3:Interacts with YPT proteins,,\n Cond876:zero2\n mHNM1:choline transport protein; may also control uptake of nitrog\nen mustard,transporter (permease) for choline and nitrogen m\nustard; share homology with UGA4,Null mutant is viable, but \nhyper-resistant to nitrogen mustard; ctr1,cho1 double null i\ns inviable\n SSD1.ANC1: Cond872:Zero1\n Cond:\n Cond885:20\n Cond889:4NQO_2\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond891:G1MMS\n mEGD1:beta subunit of the nascent-polypeptide-associated complex (\nNAC); homologous to human BTF3b; GAL4 enhancer protein,pol I\nI transcribed genes regulator,Null mutant is viable; reduced\n induction of galactose-regulated genes upon shift from gluc\nose to galactose\n mYGL080W:Unknown ,, Unknown\n mYGR106C:Unknown ,, Unknown\n mGOT1:Golgi Transport,membrane protein,Null mutant is viable but e\nxhibits ER to Golgi transport defects in vitro. got1 is synt\nhetically lethal with mutations in sft2; the got1 sft2 doubl\ne mutant exhibits defects in transport to the Golgi complex.\n Cond948:W303_ume6_YPA_\n mMCK1:Disp. for mitosis, required for chr. segregation, benomyl re\nsist., basal IME1 transcript. in mitosis, IME1 induction in \nmeiosis & ascus mat. independ. of IME1; maybe in mitotic chr\n. segregation specific to CDEIII,43.1 kDa serine/threonine/t\nyrosine protein kinase,Null mutant is viable, cold sensitive\n, temperature sensitive, and benomyl sensitive; associated w\nith delays and decreased levels of sporulation. High copy MC\nK1 acclerates early gene expression.\n mFCY1:cytosine deaminase highly homologous to Candida albicans cyt\nosine deaminase,cytosine deaminase,Mutant is resistant to 5-\nfluorocytosine and shows total loss of cytosine deaminase ac\ntivity\n Cond894:G2\n mBGL2:Cell wall endo-beta-1,3-glucanase,cell wall endo-beta-1,3-gl\nucanase,Null mutant is viable\n mERV41:ER vesicle protein,,Null mutant is viable.\n mERV25:COPII coat component of certain ER-derived vesicles,vesicle \ncoat component,Null mutant is viable, displays a selective d\nefect in transport of secretory proteins from the ER to Golg\ni complex.\n Cond893:SMMS\n mYJL178C:Unknown ,, Unknown\n mYGR182C:Unknown ,, Unknown\n Cond884:10\n
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity