Module number 2662




Database revision : gnsdb28.10
Date : Tue Feb 25 17:28:22 2003
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Cond796:Ca5'\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond399:Nitrogen_Depletion_8_h\n mYBR266C:Unknown ,, Unknown\n Cond798:Ca30'\n Cond432:YPD_stationary_phase_22_d_ypd-1\n mRPP1A:Homology to rat P1, human P1, and E.coli L12eIIA,acidic ribo\nsomal protein P1A (YP1alpha) (A1),\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n mURA7:Last step in pyrimidine biosynthesis pathway; URA7 is very s\nimilar to URA8 CTP synthase,CTP synthase,Null mutant is viab\nle; ura7 ura8 double deletion mutants are inviable\n Cond913:(99i3)_S150-2B_YPD_NormInt\n mRPL31A:Homology to rat L31,ribosomal protein L31A (L34A) (YL28),\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond697:gal2-gal\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond315:37C_to_25C_shock_-_15_min\n Cond467:steady_state_21_dec_C_ct-2\n Cond976:F82G_1_mM_1NaPP1\n Cond416:YPD_10_h__ypd-2\n mNUC1:mitochondrial nuclease,nuclease,Null mutant is viable\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond810:Na45'\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond373:1.5_mM_diamide_(40_min)\n mRPS8A:Homology to mammalian S8,ribosomal protein S8A (S14A) (rp19)\n (YS9),\n Cond445:Msn4_overexpression\n Cond890:G1\n mRRS1:Regulator for ribosome synthesis,,Null mutant is inviable. R\nsr1p depletion causes defects in pre-rRNA processing and rib\nosome assembly. The rrs1-1 mutant exhibits reduced transcrip\ntional repression of both rRNA and ribosomal protein genes.\n Cond409:diauxic_shift_timecourse_15.5_h\n mPWP1:Protein with periodic trytophan residues that resembles memb\ners of beta-transducin superfamily because of presence of WD\n-40 repeats,,Null mutants are viable but show severely retar\nded growth\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond873:10min\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n mNIP1:Protein required for nuclear import with some similarity to \nNsr1p, another protein involved in nuclear transport,,Null m\nutant is inviable; nip1-1 is a temperature-sensitive mutant \ndefective in nuclear transport\n Cond335:constant_0.32_mM_H2O2_(10_min)_redo\n Cond894:G2\n Cond395:Nitrogen_Depletion_30_min.\n Cond553:alpha14\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond569:cdc15_10\n Cond693:gal7+gal\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond430:YPD_stationary_phase_7_d_ypd-1\n Cond361:2.5mM_DTT_180_min_dtt-1\n Cond797:Ca15'\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n mEFB1:Translation elongation factor EF-1beta, GDP/GTP exchange fac\ntor for Tef1p/Tef2p,translation elongation factor EF-1beta, \nGDP/GTP exchange factor for Tef1p/Tef2p,Null mutant is invia\nble\n Cond879:MMC\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond818:crz1/Na30'\n Cond378:1M_sorbitol_-_15_min\n mNOG2:Nuclear/Nucleolar GTP-binding protein 2,part of a pre-60S co\nmplex,Null: lethal. Other phenotypes: A gal1::nog2 mutant sh\nows 60S maturation defect in glucose repressive conditions.\n Cond427:YPD_stationary_phase_2_d_ypd-1\n Cond662:mec1_plus_gamma_5_min\n mRPC40:RNA polymerase III (C) subunit,RNA polymerase III subunit,Nu\nll mutant is inviable.\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n mRPL26B:Homology to rat L26,ribosomal protein L26B (L33B) (YL33),\n Cond833:tlc1_Expt.2_Passage_5\n Cond374:1.5_mM_diamide_(50_min)\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond370:1.5_mM_diamide_(10_min)\n Cond959:t2_g/r_ratio\n Cond634:DES460_+_0.02%_MMS_-_15_min\n Cond325:29C_to_33C_-_5_minutes\n Cond809:Na30'\n mSRO9:Associates with translating ribosomes; may function in the c\nytoplasm to modulate mRNA translation; may be involved in or\nganization of actin filaments,,Null mutant is viable; multic\nopy SRO9 suppresses disappearance of cables of actin filamen\nts in both rho3 and tpm1 mutants, growth defect in tpm1 tpm2\n double mutant, and temperature sensitivity of act1-1 mutant\n; sro9 is synthetically lethal with tpm1 (but multicopy TPM2\n suppresses that synthetic lethality\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond859:ms221-30\n Cond366:dtt_120_min_dtt-2\n Cond461:21_deg_growth_ct-1\n mRLP7:Significant sequence similarity to RPL7B, but neither can fu\nnctionally replace the other. Does not correspond to any rib\nosomal component identified so far, based on its biochemical\n features,,Null mutant is inviable\n Cond881:4NQO\n Cond813:Na+FK30'\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Cond650:wt_plus_gamma_5_min\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond408:diauxic_shift_timecourse_13.5_h\n mRLI1:Strong protein homology (68% identical) to human RNase L Inh\nibitor (RLI),ATP-binding cassette (ABC) superfamily nontrans\nporter group (putative),Null mutant is inviable; overexpress\nion of RLI1 from a galactose-inducible promoter has a modera\nte inhibitory effect on growth.\n Cond652:wt_plus_gamma_20_min\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond801:CaFK15'\n Cond899:RPN4_MMS__\n mYOL124C:Unknown ,, Unknown\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond396:Nitrogen_Depletion_1_h\n Cond462:25_deg_growth_ct-1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n Cond301:Heat_Shock_10_minutes_hs-1\n Cond982:pho85D_10_mM_1NaPP1_\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond887:t-BuOOH\n mBRX1:Essential nucleolar protein required for biogenesis of the 6\n0S ribosomal subunit,,inviable\n mYOR309C:Unknown ,, Unknown\n mTIF35:Translation initiation factor 3 p33 subunit,,\n mSSF2:high copy suppressor of G beta subunit temperature sensitive\n mutation,,Null mutant is viable; displays double mutant let\nhality with ssf1 null mutations. Ssfp depletion is associate\nd with arrest of cell division and decreased mating\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n Cond363:dtt_015_min_dtt-2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n mDUS1:tRNA dihydrouridine synthase,tRNA dihydrouridine synthase,\n Cond782:Peroxide_40'\n Cond800:CaFK5'\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPSA1:mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosp\nhorylase,GDP-mannose pyrophosphorylase , mannose-1-phosphate\n guanyltransferase , GDP-mannose pyrophosphorylase , mannose\n-1-phosphate guanyltransferase , GDP-mannose pyrophosphoryla\nse , mannose-1-phosphate guanyltransferase,Null mutant is in\nviable; PSA1 is an extragenic suppressor of alg1 mutants; os\nmotically sensitive--lyses upon transfer to hypertonic condi\ntions\n Cond414:YPD_6_h_ypd-2\n Cond447:ethanol_vs._reference_pool_car-1\n Cond745: mPRS4:ribose-phosphate pyrophosphokinase 4,ribose-phosphate pyroph\nosphokinase,Null mutant is viable\n Cond386:Hypo-osmotic_shock_-_30_min\n Cond967:swi1,_YPD_(c)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n Cond463:29_deg_growth_ct-1\n Cond323:heat_shock_29_to_37,_20_minutes\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond651:wt_plus_gamma_10_min\n Cond872:Zero1\n Cond940:6h\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n mRPS11A:Homology to rat S11, human S11, and E. coli S17,ribosomal pr\notein S11A (S18A) (rp41A) (YS12),Null mutant is viable\n Cond426:YPD_stationary_phase_1_d_ypd-1\n mHMT1:hnRNP methyltransferase,arginine methyltransferase , mono- a\nnd asymmetrically dimethylating enzyme , arginine methyltran\nsferase , mono- and asymmetrically dimethylating enzyme , ar\nginine methyltransferase , mono- and asymmetrically dimethyl\nating enzyme,Null mutant is viable, hmt1 npl3-1 mutants are \ninviable\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond566:alpha105\n Cond420:YPD_3_d_ypd-2\n Cond857:pm38-gtoe\n Cond893:SMMS\n Cond379:1M_sorbitol_-_30_min\n Cond758:Heat_0'_(A)\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYLR003C:Unknown ,, Unknown\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n mRRP9:Rrp9p is an ortholog of the human U3-55k protein; the human \ncDNA partially complements a yeast rrp9 null mutant. (Pluk e\nt al. (1998) Mol. Cell. Biol. 18, 488-498.),U3 snRNP-associa\nted protein,null mutant is inviable; genetic depletion inhib\nits pre-rRNA processing at sites A0, A1 and A2, and thereby \ninhibits synthesis of 18S rRNA\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond431:YPD_stationary_phase_13_d_ypd-1\n Cond783:Peroxide_60'\n Cond878:MNNG\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n mPXR1:Unknown ,, Unknown\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n Cond882:zero3\n Cond460:17_deg_growth_ct-1\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n Cond359:2.5mM_DTT_090_min_dtt-1\n Cond417:YPD_12_h_ypd-2\n mDBP2:ATP-dependent RNA helicase of DEAD box family,ATP dependent \nRNA helicase , dead box protein,Null mutant is inviable\n Cond946:W303ume6_YPD\n Cond886:g-ray\n mDBP3:ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family,A\nTP dependent RNA helicase , dead/deah box protein CA3,Null m\nutant is viable\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n mSES1:seryl-tRNA synthetase,serine-tRNA ligase,Null mutant is invi\nable.\n Cond811:Na60'\n Cond372:1.5_mM_diamide_(30_min)\n Cond876:zero2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond324:heat_shock_33_to_37,_20_minutes\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mSAS10:Something About Silencing 10,,Null mutant is inviable; derep\nresses HMR, HML and telomeres when overexpressed\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond968:swi1,_YPD_(d)\n Cond699:gal4-gal\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond938:2h\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond559:alpha56\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond980:F82G_10_mM_1NaPP1\n mRPC19:subunit common to RNA polymerases I (A) and III (C),RNA poly\nmerases I (A) and III (C) subunit,Null mutant is inviable\n Cond858:pm71-30\n Cond979:WT_10_mM_1NaPP1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n mPWP1 mBRX1 mRPC19 mRPC40
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Computational Genomics Lab, Tel-Aviv uniresity