Module number 26




Database revision : gnsdb28.10
Date : Tue Feb 25 17:31:32 2003
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Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond277:AUR1(tetpromoter)\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond698:gal3-gal\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond221:yer083c\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n Cond164:sst2(haploid)\n Cond95:mac1\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Cond730:hda1\n Cond697:gal2-gal\n mMTD1:NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase,N\nAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase,Nu\nll mutant is viable, associated with loss of NAD-dependent 5\n,10-methylene-THF dehydrogenase activity and a purine requir\nement in some genetic backgrounds\n Cond352:1_mM_Menadione_(120_min)redo\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond244:ymr010w\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond702:gal7-gal\n Cond391:aa_starv_1_h\n Cond696:gal1-gal\n Cond517:sst2D/wtlog10(intensity)\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond393:aa_starv_4_h\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond123:rad57\n Cond704:gal80-gal\n Cond395:Nitrogen_Depletion_30_min.\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond247:ymr029c\n Cond689:gal3+gal\n Cond852:30_min\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n mSHM2:serine hydroxymethyltransferase,,Null mutant is viable\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n mLYS1:saccharopine dehydrogenase,,Lysine requiring\n Cond194:yap1\n Cond226:yhl029c\n Cond694:gal10+gal\n Cond700:gal5-gal\n Cond145:rts1\n mSNZ1:Snooze: stationary phase-induced gene family; may be involve\nd in cellular response to nutrient limitation and growth arr\nest,highly conserved 35 kDa protein that shows increased exp\nression after entry into stationary phase,Null mutant is via\nble, sensitive to 6-azauracil and methylene blue.\n Cond71:gln3\n Cond88:isw1,isw2\n Cond688:gal2+gal\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond54:erg3(haploid)\n mGCV1:Required for metabolizing glycine as a nitrogen source,glyci\nne decarboxylase complex T subunit,Null mutant is viable but\n cannot use glycine as sole nitrogen source\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n mGCV2:Glycine CleaVage system,glycine cleavage system P subunit , \nglycine decarboxylase complex P subunit , glycine synthase P\n subunit,Inability to convert glycine to serine (ser1 backgr\nound); Inability to utilize glycine as a nitogen source.\n Cond68:gas1\n Cond734: Cond116:pex12\n Cond143:rrp6\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n Cond9:ard1\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond56:erg5\n Cond69:gcn4\n Cond413:YPD_4_h_ypd-2\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond108:pac2\n Cond205:yel033w\n Cond314:Heat_Shock_060_minutes__hs-2\n Y-Stre.Alkali:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond687:gal1+gal\n Cond27:ckb2\n Cond731:hda1 \n Cond394:aa_starv_6_h\n Cond73:gyp1\n Cond691:gal5+gal\n Cond162:spf1\n Cond230:yhr022c\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Cond25:cin5\n Cond461:21_deg_growth_ct-1\n Cond690:gal4+gal\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond343:constant_0.32_mM_H2O2_(120_min)_redo\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Cond39:dig1\n Cond254:ymr044w\n Cond135:rpl20a\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond664:mec1_plus_gamma_20_min\n Cond423:YPD_stationary_phase_4_h_ypd-1\n Cond397:Nitrogen_Depletion_2_h\n Cond390:aa_starv_0.5_h\n Cond396:Nitrogen_Depletion_1_h\n Cond462:25_deg_growth_ct-1\n Cond225:yhl013c\n mARG4:argininosuccinate lyase,argininosuccinate lyase,Arginine req\nuiring\n RapamycinHap.hap_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Cond260:ymr237w\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond887:t-BuOOH\n Cond29:clb2\n Cond89:isw2\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond190:vps8\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond353:1_mM_Menadione_(160_min)_redo\n Cond2:ade2(haploid)\n Cond90:jnm1\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond53:erg2\n Cond772:Alkali_20'\n Cond6:anp1\n Cond934:8h\n Cond298:Terbinafine\n Cond920:3h\n Cond705:gal1gal10+gal\n Cond773:Alkali_40'\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond85:imp2\n Cond201:yel008w\n Cond229:yhr011w(**14)\n mSER1:phosphoserine transaminase,phosphoserine transaminase,Null m\nutant is viable, serine-requiring\n Cond271:yor051c(**14)\n mSER3:catalyzes the first step in serine biosynthesis; isozyme of \nSER33,3-phosphoglycerate dehydrogenase,enzyme activity of 3P\n-glycerate dehydrogenase is decreased in null mutant compare\nd to wildtype and abolished in ser3 ser33 double deletion mu\ntant\n Cond176:swi5\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond287:2-deoxy-D-glucose\n Cond273:yor078w\n Cond350:1_mM_Menadione_(80_min)_redo\n Cond222:yer084w\n Cond48:ecm29\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond424:YPD_stationary_phase_8_h_ypd-1\n Cond478:WT+/-10mM3AT(R491)\n Cond128:rgt1\n Cond144:rtg1\n Cond47:ecm18(**7)\n Cond43:dot4\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond24:cem1\n Cond114:pet117\n Cond132:rnr1(haploid**9)\n Cond171:ste24(haploid)\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n Cond666:mec1_plus_gamma_45_min\n Cond83:hpt1\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond342:constant_0.32_mM_H2O2_(100_min)_redo\n Cond175:swi4\n Cond250:ymr031w-a\n mSER33:catalyzes the first step in serine biosynthesis; isozyme of \nSER3,3-phosphoglycerate dehydrogenase,enzyme activity of 3P-\nglycerate dehydrogenase is decreased in null mutant compared\n to wildtype and abolished in ser3 ser33 double deletion mut\nant\n Cond686:wt+gal\n Cond284:PMA1(tetpromoter)\n Cond685:wt-gal\n Cond153:sgs1\n Cond398:Nitrogen_Depletion_4_h\n Cond738:90\n Cond667:mec1_plus_gamma_60_min\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond294:Itraconazole\n Cond159:sir3\n Cond351:1_mM_Menadione_(105_min)_redo\n Cond265:ymr293c\n Cond299:Tunicamycin\n Cond699:gal4-gal\n Cond161:sod1(haploid)\n Cond771:Alkali_10'\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond392:aa_starv_2_h\n mADE17:AICAR transformylase/IMP cyclohydrolase,5-aminoimidazole-4-c\narboxamide ribonucleotide (AICAR) transformylase/IMP cyclohy\ndrolase,Null mutant is viable; ade16 ade17 double mutants re\nquire adenine\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond665:mec1_plus_gamma_30_min\n Cond703:gal10-gal\n mSER3 mSER33
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Computational Genomics Lab, Tel-Aviv uniresity