Module number 2390




Database revision : gnsdb28.10
Date : Tue Feb 25 17:21:43 2003
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mADY2:Accumulation of DYads,,Null mutant is viable; forms predomin\nantly asci containing 2 spores (dyads) whensporulated; requi\nred for long-term growth on YPD at 37 degrees C.\n mYPL201C:Unknown ,, Unknown\n PEX.Pex:Transcriptome profiling to identify genes involved in peroxi\nsome assembly and function.  J Cell Biol. 2002 Jul 22;158(2)\n:259-71.\n mREG2:Possible regulatory subunit for the PP1 family protein phosp\nhatase Glc7p,,Null mutant is viable; reg1 reg2 double mutant\ns exhibit a severe growth defect (suppressed by loss-of-func\ntion mutation in snf1); overexpression of REG2 complements s\nlow-growth defect of a reg1 mutant but not the defects in gl\nycogen accumulation or glucose repression\n Cond698:gal3-gal\n mCRC1:carnitine carrier,carnitine transporter,Null mutant is viabl\ne\n mYBR051W:Unknown ,, Unknown\n mSPG1:Hypothetical ORF,,Null mutant is viable; SPG1 is required fo\nr long-term survival in YPD at 37 degrees C.\n Cond548:cln3-2\n Cond432:YPD_stationary_phase_22_d_ypd-1\n Cond418:YPD_1_d_ypd-2\n Cond362:dtt_000_min__dtt-2\n Cond697:gal2-gal\n mYFL030W:Unknown ,, Unknown\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mDLD1:mitochondrial enzyme D-lactate ferricytochrome c oxidoreduct\nase,D-lactate ferricytochrome c oxidoreductase,Null mutant i\ns viable and cannot grow on media containing lactate as the \nsole carbon source\n mCYB2:Expression is repressed by glucose and anaerobic conditions,\n is induced by L-lactate and is regulated by GRR1, ROX3, HAP\n1, HXK2 and CYC8,L-lactate cytochrome c oxidoreductase , cyt\nochrome b2,Null mutant is viable but is deficient in cytochr\nome b2 and L-lactate dehydrogenase activity and is unable to\n use L-lactate as a sole carbon source\n Cond414:YPD_6_h_ypd-2\n Cell Cycle.ko:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion.  Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond416:YPD_10_h__ypd-2\n Cond447:ethanol_vs._reference_pool_car-1\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond445:Msn4_overexpression\n Cond454:YP_fructose_vs_reference_pool_car-2\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYKL187C:Unknown ,, Unknown\n Cond702:gal7-gal\n Cond696:gal1-gal\n mLEE1:Product of gene unknown,,\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond457:YP_mannose_vs_reference_pool_car-2\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond704:gal80-gal\n Cond705:gal1gal10+gal\n Cond701:gal6-gal\n mMEK1:Disp. for chr. pairing & chr. condensation seen by in situ h\nybrid. Required for full double strand breaks, normal length\n synaptonemal complexes, meiotic recomb. & spore viability. \nmek1 is rescued by spo13 & in early recomb. function,meiosis\n-specific serine/threonine protein kinase,Null mutant is via\nble, however diploids homozygous for a mek1 null mutation pr\noduce only low percentages of viable spores, reduced spore v\niability is rescued by spo13 mutations\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond420:YPD_3_d_ypd-2\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond857:pm38-gtoe\n Cond689:gal3+gal\n Cond449:glucose_vs._reference_pool_car-1\n mPCK1:phosphoenolpyruvate carboxylkinase,phosphoenolpyruvate carbo\nxylkinase,Null mutant is viable.\n Cond452:sucrose_vs._reference_pool_car-1\n Cond693:gal7+gal\n Cond694:gal10+gal\n Cond430:YPD_stationary_phase_7_d_ypd-1\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond450:mannose_vs._reference_pool__car-1\n Cond419:YPD_2_d_ypd-2\n Cond700:gal5-gal\n Cond844:expt7\n Cond431:YPD_stationary_phase_13_d_ypd-1\n Cond688:gal2+gal\n Cond456:YP_glucose_vs_reference_pool_car-2\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCIT3:Mitochondrial isoform of citrate synthase,citrate synthase,N\null mutant shows severely reduced growth on the respiratory \nsubstrate glycerol in a delta cit1 background\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n mJEN1:Repressed by glucose, induced by lactic acid; in high copy, \nweakly suppresses cpr3 null mutan phenotype on lactate mediu\nm at 37 degrees,carboxylic acid transporter protein homolog,\ndeletion results in slow growth of yeast in synthetic medium\n supplemented with L-lactate and synergistic with cpr3 null \nmutation; essential for lactate uptake in yeast\n mALD6:Utilizes NADP+ as the preferred coenzyme. Activated by Mg2+.\n,aldehyde dehydrogenase,Null mutant is viable, grows at appr\noximately one-third the rate of wild-type, unable to grow on\n ethanol as a carbon source\n mYNL194C:Unknown ,, Unknown\n Cond427:YPD_stationary_phase_2_d_ypd-1\n Cond417:YPD_12_h_ypd-2\n mHSP30:Protein induced by heat shock, ethanol treatment, and entry \ninto stationary phase; located in plasma membrane,,\n Cond838:expt1\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network.  Science. 2001 May 4;292(5518\n):929-34.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond415:YPD_8_h_ypd-2\n mFBP1:fructose-1,6-bisphosphatase,fructose-1,6-bisphosphatase,unab\nle to grow with ethanol\n Cond685:wt-gal\n Cond686:wt+gal\n Cond687:gal1+gal\n Cond182:tup1(haploid)\n mRAD50:coiled-coil protein, contains a purine-binding domain, two h\neptad repeats and a hydrophobic tail,Mre11-Rad50-Xrs2 protei\nn complex member involved in joining double-stranded breaks \nand DNA recombination,Null mutant is viable but defective fo\nr X-ray damage repair, sporulation, chromosome pairing, form\nation and processing of DS breaks, gene conversion and recip\nrocal recombination in non-rDNA, tripartite synaptonemal com\nplexes and heteroduplex DNA. Exhibits blocked meiotic recomb\nination and formation of synaptonemal complex at early stage\ns. rad50-1 or null is rescued by spo13 and rescues rad52 spo\n13.\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond707:gal4gal80-gal\n Cond334:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_30_minutes\n mSIP18:Salt-Induced Protein,,Null mutant is viable.\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYIL057C:Unknown ,, Unknown\n mYGR243W:Unknown ,, Unknown\n Cond453:YP_ethanol_vs_reference_pool_car-2\n mHXT1:High-affinity hexose (glucose) transporter,high affinity hex\nose (glucose) transporter,Null mutant is viable\n Cond845:expt8\n mHXT2:hexose transporter,high affinity hexose transporter-2,Null m\nutant is viable\n mHXT3:Low-affinity glucose transporter,low affinity glucose transp\norter,Null mutant is viable but grows slowly on galactose; s\nome mutant alleles confer sodium hypersensitivity.\n Cond690:gal4+gal\n mHXT4:hexose transporter,high affinity glucose transporter,Null mu\ntant is viable\n mHXT10:high-affinity hexose transporter,high affinity hexose transp\norter,\n Cond699:gal4-gal\n mHXT6:Repression of HXT6 expression by glucose requires SNF3,hexos\ne transporter,Null mutant is viable; snf3 hxt1 hxt2 hxt3 hxt\n4 hxt6 hxt7 mutant cannot grow on media containing glucose a\ns sole carbon source\n mHXT7:Hexose transporter,hexose transporter,Null mutant is viable;\n snf3 hxt1 hxt2 hxt3 hxt4 HXT7 hxt7 mutant cannot grow on me\ndia containing glucose as sole carbon source\n mPHM7:Hypothetical ORF,,transcription is regulated by PHO system\n mAGP2:General amino acid permease with broad substrate specificity\n,amino acid permease,Null mutant is viable; loss of growth o\nn some amino acids as nitrogen source (leu, thr) in a strain\n which has no Gap1p or Agp1p function\n Cond421:YPD_5_d_ypd-2\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes.  Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond703:gal10-gal\n

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Computational Genomics Lab, Tel-Aviv uniresity