Module number 2327




Database revision : gnsdb28.10
Date : Tue Feb 25 17:11:01 2003
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mATP4:ATP synthase F0 sector subunit 4; analogous to the bovine b \nsubunit,F(1)F(0)-ATPase complex subunit b,Null mutant is via\nble but is oxidative phosphorylation deficient, is unable to\n grow on glycerol, shows an F1 loosely bound to mitochondria\nl membrane, lacks subunit 6 in F0, has a five times lower cy\ntochrome oxidase activity, produces a high percentage of spo\nnteneous rho- mutants, and is oligomycin-insensitive\n Cond899:RPN4_MMS__\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond895:G2MMS\n Cond879:MMC\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mRPB10:RNA polymerase II subunit,RNA polymerase II core subunit,Nul\nl mutant is inviable\n Cond882:zero3\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond877:MMS\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n mRPS14B:Homology to human S14 and rat S14, E. coli S11,ribosomal pro\ntein S14B (rp59B),Null mutant is viable\n Cond886:g-ray\n Cond816:Na/Na+FK30'\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mRPL26B:Homology to rat L26,ribosomal protein L26B (L33B) (YL33),\n mRPS29A:Homology to rat S29,ribosomal protein S29A (S36A) (YS29),\n mCYB5:cytochrome b5,cytochrome b5,Null mutant is viable, cyb5 muta\ntions suppress ketoconazole hypersensitivity of a P450 reduc\ntase deficient strain\n Calcin.NaNa:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYDR116C:Unknown ,, Unknown\n Cond876:zero2\n Cond943:SK1_YPA\n mYDR134C:Unknown ,, Unknown\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n Cond872:Zero1\n Cond:\n mYIL158W:Unknown ,, Unknown\n Cond885:20\n Cond889:4NQO_2\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond965:ndt80_delete_mid_g/r_ratio_\n mSHR3:Protein required for appearance of amino acid permeases on t\nhe cell surface,ER integral membrane component,Null mutants \nare viable, specifically accumulate amino acid permeases in \nthe endoplasmic reticulum\n mMRP2:14 kDa mitochondrial ribosomal protein; homologous to E. col\ni S14 protein,14 kDa mitochondrial ribosomal protein , simil\nar to E. coli S14 protein,defective mitochondrial protein sy\nnthesis; absence of a and b type cytochromes; reduced levels\n of mitochondrial 15 S rRNA; defective processing of apocyto\nchrome b intron; convert to rho- and rho0 at high frequency\n Cond891:G1MMS\n mCOX4:subunit IV of cytochrome c oxidase,cytochrome c oxidase subu\nnit IV,Null mutant is viable and unable to grow on nonfermen\ntable carbon sources\n Cond873:10min\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond805:Ca/Ca+FK30'\n Cond881:4NQO\n mFCY1:cytosine deaminase highly homologous to Candida albicans cyt\nosine deaminase,cytosine deaminase,Mutant is resistant to 5-\nfluorocytosine and shows total loss of cytosine deaminase ac\ntivity\n Cond937:t=0\n Cond894:G2\n mBGL2:Cell wall endo-beta-1,3-glucanase,cell wall endo-beta-1,3-gl\nucanase,Null mutant is viable\n Cond570:cdc15_30\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond938:2h\n mATP15:nuclear gene for ATP synthase epsilon subunit,ATP synthase e\npsilon subunit , nuclear encoded,unable to grow on glycerol \nmedium; no detectable oligomycin-sensitive ATPase activity; \noligomycin-sensitive uncoupling of the mitochondrial respira\ntion rate\n mATP16:ATP synthase delta subunit,ATP synthase delta subunit,cells \nare entirely cytoplasmic petite\n Cond672:DES459_(mec1)_-_mock_irradiation_-_60_min\n Cond893:SMMS\n mTOM6:involved in supporting the cooperativity between receptors a\nnd the general insertion pore and facilitating the release o\nf preproteins from import components,associates with TOM40 ,\n protein translocation complex component , associates with T\nOM40 , protein translocation complex component,Null mutant i\ns viable, associated with a delay of import of preproteins, \nstabilization of preprotein binding to receptors and the gen\neral insertion pore, and destabilization of the interaction \nbetween receptors and the general insertion pore; tom6 tom40\n double mutants are inviable.\n Cond466:steady_state_17_dec_C_ct-2\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond749: mRPO26:subunit common to RNA polymerases I, II, and III,RNA polymer\nases I, II, and III subunit,Null mutant is inviable\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRTN1:Unknown ,, Unknown\n Cond884:10\n
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Computational Genomics Lab, Tel-Aviv uniresity