Module number 2273




Database revision : gnsdb28.10
Date : Tue Feb 25 17:13:37 2003
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mRPT3:probable 26S protease subunit and member of the CDC48/PAS1/S\nEC18 family of ATPases,,Null mutant is inviable; yta2 is an \nextragenic suppressor of yme1 mutations\n mYNL134C:Unknown ,, Unknown\n mYDR071C:Unknown ,, Unknown\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n Cond798:Ca30'\n Cond982:pho85D_10_mM_1NaPP1_\n Cond649:dun1-_+_0.02%_MMS_-_120_min\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n mYDR533C:Unknown ,, Unknown\n Cond654:wt_plus_gamma_45_min\n mAAD6:high degree of similarity with the AAD of P. chrysosporium,a\nryl-alcohol dehydrogenase (putative),Responds to oxidative s\ntress induced by diamide and di-ethyl maleic acid ester in Y\nAP1 dependant manner\n Cond440:DBYmsn2msn4_(good_strain)_+_0.32_mM_H2O2\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond648:dun1-_+_0.02%_MMS_-_90_min\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYHR209W:Unknown ,, Unknown\n mYBR052C:Unknown ,, Unknown\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n mYDR391C:Unknown ,, Unknown\n Cond800:CaFK5'\n mYET1:Yeast BAP31 homolog,yeast endoplasmic reticulum 25 kDa trans\nmembrane protein,Null mutant is viable\n mYBL064C:Unknown ,, Unknown\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond375:1.5_mM_diamide_(60_min)\n Cond373:1.5_mM_diamide_(40_min)\n Cond371:1.5_mM_diamide_(20_min)\n Cond880:BCNU\n Cond651:wt_plus_gamma_10_min\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond802:CaFK30'\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n Cond739: Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond346:1_mM_Menadione_(20_min)_redo\n Cond376:1.5_mM_diamide_(90_min)\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond894:G2\n Cond635:DES460_+_0.02%_MMS_-_30_min\n mRPN5:Regulatory Particle Non-ATPase, homolog of mammalian proteas\nomal subunit p55,proteasome regulatory particle subunit,Null\n mutant is inviable\n Cond672:DES459_(mec1)_-_mock_irradiation_-_60_min\n Cond893:SMMS\n mRPN8:Regulatory Particle Non-ATPase, homolog of mammalian proteas\nomal subunit S12/p40,proteasome regulatory particle subunit,\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n Cond357:2.5mM_DTT_045_min_dtt-1\n Cond379:1M_sorbitol_-_30_min\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n mPRE2:proteasome subunit,proteasome subunit,Null mutant is inviabl\ne, pre2 mutants exhibit defects in chymotrypsin-like proteol\nysis, stress response and ubiquitin signaled protein degrada\ntion\n mPRE3:Proteasome subunit necessary for hydrolysis of peptidylgluta\nmyl-peptide,20S proteasome subunit,Null mutant is inviable\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPRE6:alpha-type of subunit of 20S proteasome,20S proteasome alpha\n-type subunit,Null mutant is inviable\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond797:Ca15'\n mAAD15:high degree of similarity with the AAD of P. chrysosporium,a\nryl-alcohol dehydrogenase (putative),\n mPRE9:proteasome component Y13,proteasome component Y13,\n Cond783:Peroxide_60'\n mGLC8:Homolog of mammalian protein phosphatase inhibitor 2,protein\n phosphatase 1 (Glc7p) regulator,Null mutant is viable; dele\ntion of glc8 suppresses phenotypes of ipl1 and glc7 mutants\n mUFD1:Ubiquitin fusion degradation protein,,Homozygous ufd1-1 muta\nnt diploids exhibit sporulation defects.\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n mMSP1:40 kDa putative membrane-spanning ATPase,40 kDa membrane-spa\nnning ATPase,Null mutant is viable, exhibits no observable g\nrowth defects\n Cond882:zero3\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond359:2.5mM_DTT_090_min_dtt-1\n mYNL274C:Unknown ,, Unknown\n Cond642:DES459_(mec1-)_+_0.02%_MMS_-_30_min\n mYMR090W:Unknown ,, Unknown\n Cond358:2.5mM_DTT_060_min_dtt-1\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n mSLF1:Associates with translating ribosomes; may function in cytop\nlasm to modulate mRNA translation; regulates the copper-depe\nndent mineralization of copper sulfide complexes on cell sur\nface in cells cultured in medium containing copper salts,,Nu\nll mutant is viable, copper sensitive, has lost ability to d\neplete Cu, but not Cd ions from surrounding medium; SLF1 ove\nrexpression confers copper superresistance and enhances Ca d\nepletion ability\n Cond653:wt_plus_gamma_30_min\n mGLO1:Regulated by HOG (high osmolarity glycerol)-MAP (mitogen-act\nivated protein) kinase pathway in osmotic stress response,la\nctoylglutathione lyase (glyoxalase I),Null mutant is viable;\n sensitive to methylglyoxal\n mYLR327C:Unknown ,, Unknown\n Cond349:1_mM_Menadione_(50_min)redo\n Cond374:1.5_mM_diamide_(50_min)\n Cond370:1.5_mM_diamide_(10_min)\n Cond372:1.5_mM_diamide_(30_min)\n Cond876:zero2\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond682:MHY1_(crt1)_vs_CRY1_(wild_type)\n Cond324:heat_shock_33_to_37,_20_minutes\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Cond380:1M_sorbitol_-_45_min_\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mYGL117W:Unknown ,, Unknown\n Cond348:1mM_Menadione_(40_min)_redo\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n Cond636:DES460_+_0.2%_MMS_-_45_min\n Cond659:DES460_(wt)_-_mock_irradiation_-_30_min\n mNBP35:NBP35 encodes an essential evolutionary conserved protein wi\nth homology to bacterial partitioning ATPases,35 kDa nucleot\nide binding protein,Null mutant is inviable\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mYOR289W:Unknown ,, Unknown\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond347:1_mM_Menadione_(30_min)_redo\n mHSP42:Similar to HSP26; expression is regulated by stress conditio\nns,,Null mutant is viable; hsp42 hsp26 double deletion mutan\nts are viable; hsp42 null mutants subjected to moderate ther\nmal stress reorganize the actin cytoskeleton more slowly tha\nn wild-type\n mPRC1:dispensable for haploidization and sporulation, but required\n for full protein degradation during sporulation,carboxypept\nidase Y (proteinase C),Null mutant is viable,proteinase C de\nficient\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond979:WT_10_mM_1NaPP1\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond660:DES460_(wt)_-_mock_irradiation_-_60_min\n mRPT2:Probable 26S protease subunit and member of CDC48/PAS1/SEC18\n family of ATPases,,Null mutant is inviable\n mBET4:catalyzes prenylation of Ypt1p (as a subunit of PGGTase-II),\ngeranylgeranyltransferase type II alpha subunit (PGGTase-II,\n alpha subunit),\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond801:CaFK15'\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPT2 mRPN5 mRPT3 mRPN8
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Computational Genomics Lab, Tel-Aviv uniresity