Module number 2160




Database revision : gnsdb28.10
Date : Tue Feb 25 17:06:34 2003
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Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond399:Nitrogen_Depletion_8_h\n Cond432:YPD_stationary_phase_22_d_ypd-1\n mRPP1A:Homology to rat P1, human P1, and E.coli L12eIIA,acidic ribo\nsomal protein P1A (YP1alpha) (A1),\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cond362:dtt_000_min__dtt-2\n Cond400:Nitrogen_Depletion_12_h\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond697:gal2-gal\n mRPL24B:Homology to rat L24,ribosomal protein L24B (rp29) (YL21) (L3\n0B),Null mutant is viable.\n Cond467:steady_state_21_dec_C_ct-2\n Cond416:YPD_10_h__ypd-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond810:Na45'\n mRPS29B:Homology to rat S29,ribosomal protein S29B (S36B) (YS29),\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.NaNa:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond445:Msn4_overexpression\n Cond890:G1\n mPWP1:Protein with periodic trytophan residues that resembles memb\ners of beta-transducin superfamily because of presence of WD\n-40 repeats,,Null mutants are viable but show severely retar\nded growth\n mRHR2:DL-glycerol-3-phosphatase,DL-glycerol-3-phosphatase,\n mRPS15:Homology to rat S15 and E. coli S19,ribosomal protein S15 (S\n21) (rp52) (RIG protein),\n Cond391:aa_starv_1_h\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond873:10min\n Cond805:Ca/Ca+FK30'\n mRPP2A:Homology to rat P2, human P2, and E.coli L12eIB,60S acidic r\nibosomal protein P2A (L44) (A2) (YP2alpha),Null mutant is vi\nable\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n Cond897:STATMMS\n Cond624:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y13-75\n mRPS1A:Homologous to rat S3A,ribosomal protein S1A (rp10A),\n Cond894:G2\n Cond673:DES460_(wild_type)_+_heat_20_min\n Cond395:Nitrogen_Depletion_30_min.\n Cond704:gal80-gal\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond689:gal3+gal\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n Cond849:120_min\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond430:YPD_stationary_phase_7_d_ypd-1\n Cond361:2.5mM_DTT_180_min_dtt-1\n mLHP1:Protein homologous to human La (SS-B) autoantigen,,Null muta\nnt is viable\n Cond367:dtt_240_min_dtt-2\n mYGL102C:Unknown ,, Unknown\n Cond879:MMC\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPL11B:Homology to rat L11 and E. coli L5; involved in protein synt\nhesis,ribosomal protein L11B (L16B) (rp39B) (YL22),Null muta\nnt is viable, rp111b rp111a mutants are inviable. rpl11 muta\nnts are deficient in 60S ribosomal subunits relative to 40S \nsubunits. 43S preinitiation complexes accumulate in half-mer\n polyribosomes in the absence of sufficient 60S subunits.\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond818:crz1/Na30'\n mRPS23B:Homology to rat S23 and E. coli S12,ribosomal protein S23B (\nS28B) (rp37) (YS14),Null mutant is viable, rps23a rps23b dou\nble deletion mutants are inviable. Mutations in different pa\nrts of RPS23 have opposite affects on translational accuracy\n or antibiotic sensitivity.\n Cond378:1M_sorbitol_-_15_min\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mCBR1:cytochrome b reductase,cytochrome b reductase,\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond816:Na/Na+FK30'\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mRPL26B:Homology to rat L26,ribosomal protein L26B (L33B) (YL33),\n Cond653:wt_plus_gamma_30_min\n mSIK1:homology to microtubule binding proteins and to X90565_5.cds\n,similar to microtubule binding proteins and to X90565_5.cds\n,wild-type gene suppresses toxicity of GAL4-I-Kappa-B alpha \nin yeast\n mPRP43:Pre-mRNA processing factor involved in disassembly of splice\nosomes after the release of mature mRNA,RNA helicase,\n Cond374:1.5_mM_diamide_(50_min)\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond959:t2_g/r_ratio\n mARF1:implicated in signal transduction and intracellular protein \ntransport to or within the Golgi apparatus,ADP-ribosylation \nfactor,Null mutant is viable and shows slow growth, cold sen\nsitivity and sensitivity to normally sublethal concentration\ns of fluoride ion in the medium.\n Cond809:Na30'\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond965:ndt80_delete_mid_g/r_ratio_\n mRPL10:similar to members of the QM gene family, which is implicate\nd in differentiation in other eukaryotes and tumorigenesis i\nn humans; homology to rat L10; ubiquinol-cytochrome C reduct\nase complex subunit VI requiring protein,ribosomal protein L\n10,Null mutant is inviable; temperature-sensitive mutant, at\n restrictive temperature (on rich medium), arrests after 1-3\n cell divisions as large budded cells with aberrent septum a\nnd cytoskeleton\n Cond366:dtt_120_min_dtt-2\n Cond881:4NQO\n mRPL12B:Homology to rat L12(a) and E. coli L11,ribosomal protein L12\nB (L15B) (YL23),Null mutant is viable.\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n mRPA34:RNA polymerase I subunit, not shared (A34.5),,Null mutant is\n viable but its RNA polymerase I lacks subunit A49 (rpa49p);\n synthetically lethal with RPA14; shows synthetic interactio\nns with DNA topoisomerase I (TPO1)\n Cond960:t5_g/r_ratio\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mTIF2:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mRPL34B:Homology to rat L34,ribosomal protein L34B,\n mAPT1:Adenine phosphoribosyltransferase,adenine phosphoribosyltran\nsferase,\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n mRPL27A:Homology to mammalian L27,ribosomal protein L27A,\n mRPL1B:Homology to rat L10a, eubacterial L1, and archaebacterial L1\n; identical to S. cerevisiae L1A (Ssm1p),ribosomal protein L\n1B,\n Cond652:wt_plus_gamma_20_min\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond899:RPN4_MMS__\n Cond397:Nitrogen_Depletion_2_h\n mNOP1:nucleolar protein, homologous to mammalian fibrillarin,nucle\nolar protein , similar to mammalian fibrillarin,Null mutant \nis inviable. Temperature-sensitive alleles exhibit various d\nefects in rRNA processing.\n Cond390:aa_starv_0.5_h\n mNOP2:May participate in nucleolar function during the transition \nfrom stationary phase to rapid growth,90 kDa protein homolog\nous to a human proliferation-associated nucleolar protein, p\n120,Null mutant is inviable; overexpression leads to changes\n in nucleolar morphology\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond396:Nitrogen_Depletion_1_h\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n Cond982:pho85D_10_mM_1NaPP1_\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond887:t-BuOOH\n mBRX1:Essential nucleolar protein required for biogenesis of the 6\n0S ribosomal subunit,,inviable\n mTIF34:p39 subunit of translation initiation factor eIF3,translatio\nn initiation factor eIF3 p39 subunit,Null mutant is inviable\n mRPL13B:Homology to rat L13,ribosomal protein L13B,\n Cond363:dtt_015_min_dtt-2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond941:SK1_YPD\n mRPS25B:Homology to rat S25; belongs to the S25E family of ribosomal\n proteins,ribosomal protein S25B (S31B) (rp45) (YS23),\n mRPL28:Homology to rat, mouse L27a,ribosomal protein L28 (L29) (rp4\n4) (YL24),Cycloheximide resistance\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mPSA1:mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosp\nhorylase,GDP-mannose pyrophosphorylase , mannose-1-phosphate\n guanyltransferase , GDP-mannose pyrophosphorylase , mannose\n-1-phosphate guanyltransferase , GDP-mannose pyrophosphoryla\nse , mannose-1-phosphate guanyltransferase,Null mutant is in\nviable; PSA1 is an extragenic suppressor of alg1 mutants; os\nmotically sensitive--lyses upon transfer to hypertonic condi\ntions\n Cond414:YPD_6_h_ypd-2\n Cond892:S\n Cond745: Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond463:29_deg_growth_ct-1\n mYHR020W:Unknown ,, Unknown\n mRPL2B:Homology to rat L8 and E. coli L2,ribosomal protein L2B (L5B\n) (rp8) (YL6),\n Cond323:heat_shock_29_to_37,_20_minutes\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond880:BCNU\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond872:Zero1\n Cond651:wt_plus_gamma_10_min\n Cond940:6h\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n mRPL30:Homology to rat and mouse L30,ribosomal protein L30 (L32) (r\np73) (YL38) large subunit,Null mutant is inviable.\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond961:t7_g/r_ratio\n Cond420:YPD_3_d_ypd-2\n Cond857:pm38-gtoe\n Cond893:SMMS\n mRPL43A:Homology to human L37a,ribosomal protein L43A,\n Cond379:1M_sorbitol_-_30_min\n mRPO26:subunit common to RNA polymerases I, II, and III,RNA polymer\nases I, II, and III subunit,Null mutant is inviable\n Cond354:2.5mM_DTT_005_min_dtt-1\n mCBF5:major low affinity 55 kDa Centromere/microtubule binding pro\ntein,major low affinity 55 kDa centromere/microtubule bindin\ng protein,Null mutant is inviable\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n RapamycinDip.dip_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Cond434:DBY7286_37degree_heat_-_20_min\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond589:cdc15_240\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond431:YPD_stationary_phase_13_d_ypd-1\n mARX1:Unknown ,, Unknown\n Cond783:Peroxide_60'\n Cond895:G2MMS\n Cond878:MNNG\n Cond882:zero3\n Cond460:17_deg_growth_ct-1\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n Cond417:YPD_12_h_ypd-2\n Cond946:W303ume6_YPD\n Cond886:g-ray\n mDBP3:ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family,A\nTP dependent RNA helicase , dead/deah box protein CA3,Null m\nutant is viable\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n Cond685:wt-gal\n Cond402:Nitrogen_Depletion_2_d\n Cond811:Na60'\n Cond372:1.5_mM_diamide_(30_min)\n Cond876:zero2\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond401:Nitrogen_Depletion_1_d\n Cond885:20\n mVMA7:vacuolar H-ATPase 14 kDa subunit (subunit F) of the catalyti\nc (V1) sector,vacuolar ATPase V1 domain subunit F (14 kDa),N\null mutant is viable, unable to grow on media buffered at pH\n 7.5, fails to accumulate quinacrine into vacuoles, other su\nbunits of the catalytic sector are not assembled onto the va\ncuolar membrane\n mHAS1:Helicase Associated with SET1,RNA-dependent helicase (putati\nve),Null mutant is inviable\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond453:YP_ethanol_vs_reference_pool_car-2\n mSUR4:Required for conversion of 24-carbon fatty acids to 26-carbo\nn species,,Null mutants is viable, not sensitive to UV or ga\nmma radiation. sur4 mutants suppress rad3, rvs161 delta, and\n rvs167 mutations. sur4 fen1 mutants and sur4 elo2 mutants a\nre inviable.\n Cond699:gal4-gal\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond421:YPD_5_d_ypd-2\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond858:pm71-30\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond884:10\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n mNOP1 mSIK1 mNOP2 mCBF5 mPWP1 mBRX1
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Computational Genomics Lab, Tel-Aviv uniresity