Module number 2110




Database revision : gnsdb28.10
Date : Tue Feb 25 17:46:09 2003
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mSPC2:subunit of signal peptidase complex, homologous to mammalian\n protein SPC25,signal peptidase complex subunit , similar to\n mammalian protein SPC25,Null mutant is viable. spc1 spc2 do\nuble deletion mutants grow relatively well as compared to wi\nld-type. spc2 sec11 double deletion mutant is inviable. Spc2\np is important for cell viability and signal peptidase activ\nity at high temperatures (42 degrees celsius).\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond792:Sorbitol_45'\n Cond462:25_deg_growth_ct-1\n Cond791:Sorbitol_30'\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mYNR024W:Unknown ,, Unknown\n mPOP4:Required for normal 5.8S rRNA processing and for tRNA proces\nsing; associated with RNase MRP and RNase P,,Null mutant is \ninviable\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n Cond585:cdc15_200\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n mYKL063C:Unknown ,, Unknown\n Cond761:Heat_30'\n mEBP2:EBNA1-binding protein homolog,nucleolar protein,Null mutant \nis inviable\n Y-Stre.msn2/4acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mSRP102:Signal recognition particle receptor beta subunit,,Null muta\nnt is viable but exhibits slow growth and cannot grow on non\nfermentable carbon sources. Temperature-sensitive alleles ex\nhibit defects in translocation of some ER proteins at the no\nnpermissive temperature.\n Cond883:5\n Cond573:cdc15_80\n Cond505:wtħ50nMaF,120minlog10(intensity)\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond355:2.5mM_DTT_015_min_dtt-1\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond486:PHO4c_vs_WT\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond587:cdc15_220\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n mMGE1:involved in protein import into mitochondria,GrpE homolog,Nu\nll mutant is inviable\n Cond900:(11i1)_S150-2B_YPGL_NormInt\n Cond934:8h\n Cond59:erp4\n Cond902:(77i1)_HBY4_YPGL_NormInt\n Cond646:DES459_(mec1-)_+_0.02%_MMS_-_120_min\n Cond569:cdc15_10\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond717:t2-SSD1\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond589:cdc15_240\n Cond720:t0+SSD1,H44\n Cond762:Heat_45'\n Cond777:msn2/4_acid_0'\n Cond278:CDC42(tetpromoter)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mYER030W:Unknown ,, Unknown\n Cond906:(77i5)_S150-2B_YPD_NormInt\n Cond904:(77i3)_HBY4_YPGL+G_NormInt\n Y-Stre.Sorbitol:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond661:DES460_(wt)_-_mock_irradiation_-_90_min\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mTAF4:Protein required for protein synthesis,TFIID subunit,Null mu\ntant is inviable\n Cond398:Nitrogen_Depletion_4_h\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRFC5:RFC is a multisubunit DNA binding protein and ATPase that ac\nts as a processivity factor for DNA polymerases delta and ep\nsilon and loads proliferating cell nuclear antigen (PCNA) on\n DNA,replication factor C subunit 5 , similar to human RFC 3\n8 kDa subunit,Null mutant is inviable\n Cond634:DES460_+_0.02%_MMS_-_15_min\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n mSRP21:part of the signal recognition particle (SRP) ribonucleoprot\nein (RNP) complex that functions in protein targeting to the\n endoplasmic reticulum (ER) membrane,signal recognition part\nicle component,Null mutant is viable, associated with slow c\nell growth and inefficient protein translocation across the \nER membrane\n mRRP45:Ribosomal RNA Processing,3'->5' exoribonuclease,Null mutant \nis inviable; mutant is defective in 3' processing of 5.8S rR\nNA\n Cond905:(77i4)_S150-2B_YPGL+G__NormInt\n mMIA1:Hypothetical ORF,mitochondrial protein of unknown function,N\null mutant is inviable; MIA1 is required for respiration\n Cond461:21_deg_growth_ct-1\n mMRT4:mRna turnover 4,,Null mutant exhibits slow growth. ts mutat\nion results in decreased decay rates of mRNAs\n Cond570:cdc15_30\n mYPL146C:Unknown ,, Unknown\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond584:cdc15_190\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond577:cdc15_120\n Cond660:DES460_(wt)_-_mock_irradiation_-_60_min\n Cond790:Sorbitol_15'\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity