Module number 2046




Database revision : gnsdb28.10
Date : Tue Feb 25 17:46:46 2003
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UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond944:SK1_ume6_YPA\n mSSU72:functionally related to TFIIB, affects start site selection \nin vivo,,Null mutant is inviable\n Cond895:G2MMS\n mYMR031C:Unknown ,, Unknown\n Cond563:alpha84\n Cond877:MMS\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n mGFD1:Great for FULL DEAD box protein activity,,Null mutant is via\nble; high copy suppressor of rat8-2\n mCRZ1:calcineurin responsive zinc-finger,transcription factor (put\native),Null mutant is viable\n mKAR5:appears to be required for the completion of nuclear membran\ne fusion and may play a role in the organization of the memb\nrane fusion complex,coiled-coil membrane protein,Null mutant\n is viable, mating defective, nuclear fusion defective\n Cond886:g-ray\n Cond579:cdc15_140\n mMKS1:Pleiotropic regulatory factor involved in Ras-CAMP and lysin\ne biosynthetic pathways and nitrogen regulation,negative tra\nnsctiptional regulator,Null mutant is viable, fails to grow \non galactose media containing ethidium bromide at 25 degrees\n and on YPglycerol media at 37 degrees\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond892:S\n Cond876:zero2\n Cond885:20\n Cond715:t0-SSD1\n Cond889:4NQO_2\n mYDR003W:Unknown ,, Unknown\n Cond891:G1MMS\n mYMR115W:Unknown ,, Unknown\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mAPG13:autophagy,,Defective in autophagy\n mYMR124W:Unknown ,, Unknown\n mSPT20:Transcription factor,histone acetyltransferase SAGA complex \nmember , transcription factor,Null mutant is viable, exhibit\ns growth defects on glucose and galactose, fails to grow on \nmedia lacking inositol\n mNUP85:Protein in nuclear pore complex; may function in nuclear env\nelope integrity; may also be involved in tRNA biogenesis,,Nu\nll mutant is viable but is temperature-sensitive; at nonperm\nissive temperature, null mutant accumulates poly(A)+ RNA and\n has fragmented nucleolus; at permissive temperature, nuclea\nr envelope of null mutant detaches from nucleus\n mRSC8:Rsc8 is the eighth largest subunit of RSC, a fifteen-protein\n chromatin remodeling complex and related to the Swi/snf Com\nplex.,,Null mutant is inviable\n Cond881:4NQO\n mYOR059C:Unknown ,, Unknown\n Cond888:MNNG_2\n mNFU1:Nifu-like protein,,Null mutant is viable on YPD 30 degrees C\n, and is synthetically lethal with SSQ1\n Cond894:G2\n Cell Cycle.cdc15:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Cond893:SMMS\n Cond884:10\n
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Computational Genomics Lab, Tel-Aviv uniresity