Module number 190




Database revision : gnsdb28.10
Date : Tue Feb 25 17:30:38 2003
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Cond158:sir2\n Cond277:AUR1(tetpromoter)\n Cond476:GCN4C/GCN4(R4760/R6257)\n Cond221:yer083c\n Cond225:yhl013c\n Cond104:npr2\n mMCH1:Unknown ,, Unknown\n Cond260:ymr237w\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond164:sst2(haploid)\n Cond29:clb2\n Cond183:ubp8\n Cond130:rml2(**13)\n Cond13:ase1(**12)\n Cond89:isw2\n Cond224:CMD1(tetpromoter)\n Cond730:hda1\n Cond190:vps8\n Cond31:cmk2\n Cond244:ymr010w\n mARO9:aromatic amino acid aminotransferase II,aromatic amino acid \naminotransferase II,Null mutant is viable\n Cond124:rad6(haploid)\n Cond90:jnm1\n Cond297:Nikkomycin\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond30:clb6\n Cond53:erg2\n mFRM2:Protein involved in the integration of lipid signaling pathw\nays with cellular homeostatis,,Null mutant is viable and sen\nsitive to arachidonic acid\n mYOL118C:Unknown ,, Unknown\n Cond517:sst2D/wtlog10(intensity)\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond6:anp1\n Cond123:rad57\n Cond119:ppr1\n Cond298:Terbinafine\n Cond279:ERG11(tetpromoter)\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n Cond247:ymr029c\n Cond61:fks1(haploid)\n Cond229:yhr011w(**14)\n Cond70:gfd1\n Cond216:yer044c(haploid)\n Cond86:imp2'(**12)\n Cond271:yor051c(**14)\n Cond479:WT+/-100mM3AT(SetD)(R491)\n mICY2:Interacting with the cytoskeleton,,\n Cond57:erg6\n Cond176:swi5\n mLYS1:saccharopine dehydrogenase,,Lysine requiring\n Cond482:WT+/-100mM3AT(SetC)(KNY164)\n Cond226:yhl029c\n Cond194:yap1\n mLYS2:alpha aminoadipate reductase,alpha aminoadipate reductase,Nu\nll mutant is viable, lysine auxotroph\n Cond287:2-deoxy-D-glucose\n mADH5:alcohol dehydrogenase isoenzyme V,alcohol dehydrogenase isoe\nnzyme V,\n mMET13:putative methylenetetrahydrofolate reductase (mthfr),methyle\nnetetrahydrofolate reductase (mthfr) (putative),Null mutant \nis viable and shows methionine auxotrophy; double disruption\n of MET12 and MET13 (the two putative mthfr genes) also conf\ners methionine auxotrophy, but has no other known phenotype \nat this time.\n mATR1:aminotriazole resistance,very hydrophobic, has many membrane\n-spanning regions, several potential glycosylation sites, po\ntential ATP-binding site,Null mutant is viable, but is sensi\ntive to very low (5 mM) levels of aminotriazole and to 4-nit\nroquinoline-N-oxide (4-NQO); multiple copies of ATR1 confer \nhyper-resistance to 4-NQO; multiple copies of ATR1 in gcn4 b\nackground confer resistance to high (80mM) levels of aminotr\niazole\n Cond48:ecm29\n Cond478:WT+/-10mM3AT(R491)\n Cond128:rgt1\n Cond145:rts1\n Cond258:ymr147w\n Cond144:rtg1\n mTRP5:tryptophan synthetase,tryptophan synthetase,Null mutant is v\niable and requires tryptophan\n mSNZ1:Snooze: stationary phase-induced gene family; may be involve\nd in cellular response to nutrient limitation and growth arr\nest,highly conserved 35 kDa protein that shows increased exp\nression after entry into stationary phase,Null mutant is via\nble, sensitive to 6-azauracil and methylene blue.\n Cond150:sbh2\n Cond71:gln3\n Cond88:isw1,isw2\n Cond47:ecm18(**7)\n Cond139:rpl8a\n mAMA1:Required for sporulation, highly induced during sporulation;\n activator of meiotic anaphase promoting complex,,Null mutan\nt is viable; homozygous null mutant does not sporulate but d\noes not exhibit any vegetative phenotype.\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond233:yhr039c\n Cond132:rnr1(haploid**9)\n mSNO1:SNZ1 proximal ORF, stationary phase induced gene,,Null mutan\nt is viable, sensitive to 6-azauracil and methylene blue.\n Cond68:gas1\n Cond171:ste24(haploid)\n Cond116:pex12\n Cond117:pfd2(**14)\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n Cond9:ard1\n mILV6:acetolactate synthase regulatory subunit,,\n Cond175:swi4\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond108:pac2\n Cond250:ymr031w-a\n mPDX3:pyridoxine (pyridoxiamine) phosphate oxidase,pyridoxine (pyr\nidoxiamine) phosphate oxidase,\n Cond205:yel033w\n mTMT1:Trans-aconitate Methyltransferase 1,,\n Cond14:ate1\n Cond91:kim4\n Cond153:sgs1\n Cond252:ymr040w\n Cond27:ckb2\n Cond73:gyp1\n Cond162:spf1\n Cond230:yhr022c\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond92:kin3\n Cond294:Itraconazole\n mYPL033C:Unknown ,, Unknown\n Cond25:cin5\n Cond159:sir3\n mSHR5:Involved in RAS localization and palmitoylation,,Null mutant\n is viable; exhibits normal palmityltransferase activity in \nvitro and attenuates Ras function in cells with mutant Ras2 \nproteins that are not farnesylated or palmitoylated; shr5 mu\ntation originally isolated as suppressor of Ras function\n Cond295:Lovastatin\n Cond51:eft2\n mYBR047W:Unknown ,, Unknown\n Cond299:Tunicamycin\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond274:yor080w(**3)\n Cond186:utr4\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond39:dig1\n Cond160:sir4\n Cond135:rpl20a\n mYFL040W:Unknown ,, Unknown\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n mSNO1 mSNZ1
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Computational Genomics Lab, Tel-Aviv uniresity