Module number 1807




Database revision : gnsdb28.10
Date : Tue Feb 25 17:22:09 2003
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Cond796:Ca5'\n Cond399:Nitrogen_Depletion_8_h\n Cond798:Ca30'\n Cond432:YPD_stationary_phase_22_d_ypd-1\n mYOR145C:Unknown ,, Unknown\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n mFPR4:Homolog of homolog of the nucleolar FKBP, Fpr3,peptidyl-prol\nyl cis-trans isomerase (PPIase),Null mutant is viable\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n Cond834:tlc1_Expt.2_Passage_6\n Cond697:gal2-gal\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond416:YPD_10_h__ypd-2\n Cond810:Na45'\n Cond637:DES460_+_0.02%_MMS_-_60_min\n Cond890:G1\n mRSA3:RiboSome Assembly,,\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond873:10min\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n Cond673:DES460_(wild_type)_+_heat_20_min\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond430:YPD_stationary_phase_7_d_ypd-1\n mCGR1:coiled-coil growth-regulated,coiled-coil protein,Null mutant\n is inviable; CGR1 expression is down-regulated in the postd\niauxic growth phase\n Cond879:MMC\n mRPL11A:Homology to rat L11 and E. coli L5,ribosomal protein L11A (L\n16A) (rp39A) (YL22),\n Cond427:YPD_stationary_phase_2_d_ypd-1\n Cond662:mec1_plus_gamma_5_min\n mYLR435W:Unknown ,, Unknown\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond945:W303_YPD\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond833:tlc1_Expt.2_Passage_5\n mYGR272C:Unknown ,, Unknown\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond461:21_deg_growth_ct-1\n Cond881:4NQO\n Cond813:Na+FK30'\n Cond485:Low-Pi_vs_High-Pi_in_WT_(DBY7286)\n Cond303:Heat_Shock_20_minutes_hs-1\n mRPA34:RNA polymerase I subunit, not shared (A34.5),,Null mutant is\n viable but its RNA polymerase I lacks subunit A49 (rpa49p);\n synthetically lethal with RPA14; shows synthetic interactio\nns with DNA topoisomerase I (TPO1)\n Cond636:DES460_+_0.2%_MMS_-_45_min\n mMRT4:mRna turnover 4,,Null mutant exhibits slow growth. ts mutat\nion results in decreased decay rates of mRNAs\n Cond639:DES460_+_0.02%_MMS_-_120_min\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n Cond441:DBYmsn2/4_(real_strain)_+_0.32_mM_H2O2_(20_min)\n mTIF2:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mYMR321C:Unknown ,, Unknown\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond801:CaFK15'\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n mYIL127C:Unknown ,, Unknown\n Cond316:37C_to_25C_shock_-_30_min\n Cond462:25_deg_growth_ct-1\n Cond982:pho85D_10_mM_1NaPP1_\n Cond301:Heat_Shock_10_minutes_hs-1\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond887:t-BuOOH\n mRPB10:RNA polymerase II subunit,RNA polymerase II core subunit,Nul\nl mutant is inviable\n mYOR309C:Unknown ,, Unknown\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond941:SK1_YPD\n mRPL28:Homology to rat, mouse L27a,ribosomal protein L28 (L29) (rp4\n4) (YL24),Cycloheximide resistance\n mRPS18B:Homology to rat S18 and E. coli S13,ribosomal protein S18B,\n mYBL028C:Unknown ,, Unknown\n Cond745: Cond371:1.5_mM_diamide_(20_min)\n Cond463:29_deg_growth_ct-1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond872:Zero1\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond326:29C_to_33C_-_15_minutes\n Cond855:pm38-30\n Cond638:DES460_+_0.02%_MMS_-_90_min\n Cond635:DES460_+_0.02%_MMS_-_30_min\n Cond857:pm38-gtoe\n mSUI3:beta subunit of translation initiation factor eIF-2,translat\nion initiation factor eIF-2 beta subunit,suppression of init\niator codon mutations\n mCBF5:major low affinity 55 kDa Centromere/microtubule binding pro\ntein,major low affinity 55 kDa centromere/microtubule bindin\ng protein,Null mutant is inviable\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond419:YPD_2_d_ypd-2\n Cond431:YPD_stationary_phase_13_d_ypd-1\n mPXR1:Unknown ,, Unknown\n Cond882:zero3\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n mNHP2:HMG-like nuclear protein,HMG-like protein,Null mutant is inv\niable\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n mDBP2:ATP-dependent RNA helicase of DEAD box family,ATP dependent \nRNA helicase , dead box protein,Null mutant is inviable\n mDBP8:Dead-Box Protein 8, ATP-dependent helicase involved in rRNA \nprocessing,dead box protein,Null mutant is inviable\n mDBP9:Dead-Box Protein 9,,Null mutant is inviable\n Cond811:Na60'\n mYOR252W:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond324:heat_shock_33_to_37,_20_minutes\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond968:swi1,_YPD_(d)\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond980:F82G_10_mM_1NaPP1\n mCDC33:Required for START A of cell cycle and sporulation,mRNA cap \nbinding protein eIF-4E,Null mutant is inviable. cdc33 mutant\ns arrest at G(sub)1. cdc33 has normal cAMP pools and is not \nsuppressed by cAPK mutants, suggesting sporulation is indepe\nndent of the cAMP pathway\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n mGAR1:small nucleolar RNP proteins,small nucleolar RNP protein,Nul\nl mutant is inviable\n Cond663:mec1_plus_gamma_10_min\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mYPR044C:Unknown ,, Unknown\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n mRPS0B:Homology to rat Sa; closely related to mammalian p40/laminin\n receptor precursors (LRPs); required for translation and co\nntributes to the assembly and/or stability of the 40S riboso\nmal subunit,ribosomal protein S0B,Null mutant is viable with\n significant reduction in growth rate and change in distribu\ntion and make up of ribosomes; yst1 (rps0a) yst2 (rps0b) dou\nble mutant is inviable\n mNSA2:Killer toxin Resistant; Nop seven associated protein 2,ribos\nome biogenesis,Heterozygous diploid mutant exhibit haploinsu\nfficiency K1 killer toxin resistance\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPL24A:Homology to rat L24,ribosomal protein L24A (rp29) (YL21) (L3\n0A),Null mutant is viable.\n mRPL24B:Homology to rat L24,ribosomal protein L24B (rp29) (YL21) (L3\n0B),Null mutant is viable.\n Cond315:37C_to_25C_shock_-_15_min\n mYPL238C:Unknown ,, Unknown\n Cond467:steady_state_21_dec_C_ct-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPS29B:Homology to rat S29,ribosomal protein S29B (S36B) (YS29),\n Cond373:1.5_mM_diamide_(40_min)\n mRPB8:16-kDa RNA polymerase subunit (common to polymerases I, II a\nnd III),16 kDa RNA polymerase subunit (common to polymerases\n I, II and III),Null mutant is inviable\n Cond391:aa_starv_1_h\n Cond814:Na+FK45'\n mYPL245W:Unknown ,, Unknown\n Cond805:Ca/Ca+FK30'\n Cond769:Acid_80'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond894:G2\n Cond395:Nitrogen_Depletion_30_min.\n mYKL082C:Unknown ,, Unknown\n mNIP7:Nip7p is required for 60S ribosome subunit biogenesis,,Null \nmutant is inviable; in the temperature-sensitive mutant nip7\n-1, glycine 71 is replaced by aspartic acid\n Cond749: mRPL18B:Homology to rat ribosomal protein L18,ribosomal protein L18B\n (rp28B),\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond797:Ca15'\n Cond361:2.5mM_DTT_180_min_dtt-1\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond367:dtt_240_min_dtt-2\n mRPL7A:Homology to rat L7 and E. coli L30,ribosomal protein L7A (L6\nA) (rp11) (YL8),Null mutant is viable; grows more slowly tha\nn wild-type\n mYLR413W:Unknown ,, Unknown\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond385:Hypo-osmotic_shock_-_15_min\n Cond818:crz1/Na30'\n Cond378:1M_sorbitol_-_15_min\n mRPL33A:Homology to rat L35a,ribosomal protein L33A (L37A) (YL37) (r\np47),Null mutant is viable, severely impaired in growth. rpl\n33a rpl33b double deletion mutants are inviable\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mRPL26B:Homology to rat L26,ribosomal protein L26B (L33B) (YL33),\n mRPS3:Homology to mammalian S3,ribosomal protein S3 (rp13) (YS3),N\null mutant is inviable\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond374:1.5_mM_diamide_(50_min)\n Cond959:t2_g/r_ratio\n Cond809:Na30'\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond859:ms221-30\n Cond366:dtt_120_min_dtt-2\n mRLP7:Significant sequence similarity to RPL7B, but neither can fu\nnctionally replace the other. Does not correspond to any rib\nosomal component identified so far, based on its biochemical\n features,,Null mutant is inviable\n Cond690:gal4+gal\n mKRI1:KRRI-Interacting protein 1,Krr1p binding protein,\n Calcin.Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond650:wt_plus_gamma_5_min\n Cond652:wt_plus_gamma_20_min\n Cond899:RPN4_MMS__\n mNOP1:nucleolar protein, homologous to mammalian fibrillarin,nucle\nolar protein , similar to mammalian fibrillarin,Null mutant \nis inviable. Temperature-sensitive alleles exhibit various d\nefects in rRNA processing.\n Cond396:Nitrogen_Depletion_1_h\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n mYPR142C:Unknown ,, Unknown\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mRPL9A:Homology to rat L9,ribosomal protein L9A (L8A) (rp24) (YL11)\n,\n mRAS1:ras proto-oncogene homolog,ras homolog,\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n Cond363:dtt_015_min_dtt-2\n Cond782:Peroxide_40'\n mEBP2:EBNA1-binding protein homolog,nucleolar protein,Null mutant \nis inviable\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond892:S\n Cond447:ethanol_vs._reference_pool_car-1\n mMPP10:Protein component of the U3 small nucleolar ribonucleoprotei\nn (snoRNP),U3 snoRNP protein,Null mutant is inviable\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond967:swi1,_YPD_(c)\n Cond323:heat_shock_29_to_37,_20_minutes\n mYNL174W:Unknown ,, Unknown\n mYNL247W:Unknown ,, Unknown\n Y-Stre.Acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mRPF2:Hypothetical ORF,,\n mSNU13:RNA binding protein (putative), similar to Nhp2p,U4/U6.U5 sn\nRNP component,the null mutant is inviable\n Cond426:YPD_stationary_phase_1_d_ypd-1\n mEFT1:translation elongation factor 2 (EF-2),translation elongatio\nn factor 2 (EF-2),Null mutant is viable (eft1 eft2 double mu\ntant is lethal)\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond420:YPD_3_d_ypd-2\n Cond893:SMMS\n Cond379:1M_sorbitol_-_30_min\n mRPO26:subunit common to RNA polymerases I, II, and III,RNA polymer\nases I, II, and III subunit,Null mutant is inviable\n Cond758:Heat_0'_(A)\n Cond354:2.5mM_DTT_005_min_dtt-1\n mYPR143W:Unknown ,, Unknown\n mRRP6:Ribosomal RNA Processing,,Null mutant is viable, heat sensit\nive; other mutants show a 5.8S rRNA 3' end formation defect\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond434:DBY7286_37degree_heat_-_20_min\n mYLR003C:Unknown ,, Unknown\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond783:Peroxide_60'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n mPUS7:Unknown ,, Unknown\n Cond460:17_deg_growth_ct-1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond417:YPD_12_h_ypd-2\n Cond946:W303ume6_YPD\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n mYKR060W:Unknown ,, Unknown\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond876:zero2\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond885:20\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond411:diauxic_shift_timecourse_20.5_h\n Cond699:gal4-gal\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n mWRS1:W = IUPAC for tryptophan, RS = convention for aminoacyl-tRNA\n synthetases,tryptophan-tRNA ligase,Null mutant is inviable\n Cond938:2h\n mYOR021C:Unknown ,, Unknown\n Cond421:YPD_5_d_ypd-2\n mYDR412W:Unknown ,, Unknown\n Cond858:pm71-30\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPS7B:Homology to human S7 and Xenopus S8,ribosomal protein S7B (r\np30),\n mNHP2 mGAR1 mDBP8 mTIF2 mCDC33
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Computational Genomics Lab, Tel-Aviv uniresity