Module number 1766




Database revision : gnsdb28.10
Date : Tue Feb 25 17:26:16 2003
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Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Cond399:Nitrogen_Depletion_8_h\n Cond432:YPD_stationary_phase_22_d_ypd-1\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond675:MHY1_(dun1)_+_heat_20_min\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n Cond400:Nitrogen_Depletion_12_h\n Cond697:gal2-gal\n Cond416:YPD_10_h__ypd-2\n Cond810:Na45'\n Calcin.NaNa:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mRPS8A:Homology to mammalian S8,ribosomal protein S8A (S14A) (rp19)\n (YS9),\n Cond890:G1\n Cond:\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond873:10min\n mRPP2A:Homology to rat P2, human P2, and E.coli L12eIB,60S acidic r\nibosomal protein P2A (L44) (A2) (YP2alpha),Null mutant is vi\nable\n mRPP2B:Homology to rat P2, human P2, and E.coli L12eIA,ribosomal pr\notein P2B (YP2beta) (L45),Null mutant is viable\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n Cond480:WT+/-100mM3AT(SetA)(R491)\n mRPS22A:Homology to rat S15a,ribosomal protein S22A (S24A) (rp50) (Y\nS22),\n Cond673:DES460_(wild_type)_+_heat_20_min\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond404:Nitrogen_Depletion_5_d\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond689:gal3+gal\n Cond693:gal7+gal\n Cond849:120_min\n Cond430:YPD_stationary_phase_7_d_ypd-1\n Cond700:gal5-gal\n Cond879:MMC\n mRPL11B:Homology to rat L11 and E. coli L5; involved in protein synt\nhesis,ribosomal protein L11B (L16B) (rp39B) (YL22),Null muta\nnt is viable, rp111b rp111a mutants are inviable. rpl11 muta\nnts are deficient in 60S ribosomal subunits relative to 40S \nsubunits. 43S preinitiation complexes accumulate in half-mer\n polyribosomes in the absence of sufficient 60S subunits.\n Cond422:YPD_stationary_phase_2_h_ypd-1\n mRPS23A:Homology to rat S23 and E. coli S12,ribosomal protein S23A (\nS28A) (rp37) (YS14),Null mutant is viable; rps23a rps23b dou\nble deletion mutants are inviable. Mutations in different pa\nrts of RPS23 have opposite affects on translational accuracy\n or antibiotic sensitivity.\n mRPS23B:Homology to rat S23 and E. coli S12,ribosomal protein S23B (\nS28B) (rp37) (YS14),Null mutant is viable, rps23a rps23b dou\nble deletion mutants are inviable. Mutations in different pa\nrts of RPS23 have opposite affects on translational accuracy\n or antibiotic sensitivity.\n Cond427:YPD_stationary_phase_2_d_ypd-1\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond746: Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond653:wt_plus_gamma_30_min\n Cond833:tlc1_Expt.2_Passage_5\n Cond687:gal1+gal\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond969:swi1,_minimal_(a)\n Cond942:SK1ume6_YPD\n Cond742: Cond881:4NQO\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n mRPL5:Homology to rat ribosomal protein L5; required for assembly \nof stable 60S ribosomal subunits,ribosomal protein L5 (L1a)(\nYL3),Null mutant is inviable.\n Cond960:t5_g/r_ratio\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n mTIF1:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mTIF2:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mTIF3:Suppressor of translation mutants,translation initiation fac\ntor eIF-4B,\n mGUA1:GMP synthase,GMP synthase,Null mutant is viable but is a gua\nnine auxotroph\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n mRPL1A:Homology to rat L10a, eubacterial L1, and archaebacterial L1\n; identical to S. cerevisiae L1B (Ssm2p),ribosomal protein L\n1A, forms part of the 60S ribosomal subunit,Null mutant is v\niable; shows double mutant lethality with rpl1b (ssm2b) null\n mutants\n mRPL1B:Homology to rat L10a, eubacterial L1, and archaebacterial L1\n; identical to S. cerevisiae L1A (Ssm1p),ribosomal protein L\n1B,\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond397:Nitrogen_Depletion_2_h\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond982:pho85D_10_mM_1NaPP1_\n Cond887:t-BuOOH\n mRPL20A:Homology to rat L18a,ribosomal protein L20A (L18A),\n mRPL20B:Homology to rat L18a,ribosomal protein L20B (L18B),\n mRPL13B:Homology to rat L13,ribosomal protein L13B,\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond941:SK1_YPD\n Cond971:swi1,_minimal_(d)_\n Cond745: Cond463:29_deg_growth_ct-1\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond880:BCNU\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond651:wt_plus_gamma_10_min\n Cond872:Zero1\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond532:GAL-RHO1-Q68H,3hrs.gallog10(intensity)\n Cond705:gal1gal10+gal\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond857:pm38-gtoe\n mRPL38:Homology to rat L38,ribosomal protein L38,\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n RapamycinDip.dip_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Cond419:YPD_2_d_ypd-2\n Cond431:YPD_stationary_phase_13_d_ypd-1\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond882:zero3\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n Cond886:g-ray\n Cond403:Nitrogen_Depletion_3_d\n Cond811:Na60'\n Cond372:1.5_mM_diamide_(30_min)\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond336:constant_0.32_mM_H2O2_(20_min)_redo\n Cond401:Nitrogen_Depletion_1_d\n Cond265:ymr293c\n mTEF4:Translation elongation factor EF-1gamma,translation elongati\non factor EF-1gamma,\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond453:YP_ethanol_vs_reference_pool_car-2\n Cond968:swi1,_YPD_(d)\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond962:t9_g/r_ratio\n mRPS28B:Homology to mammalian S28,ribosomal protein S28B (S33B) (YS2\n7),\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Cond884:10\n Cond703:gal10-gal\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond698:gal3-gal\n Cond221:yer083c\n Cond565:alpha98\n mSSB2:stress-seventy subfamily B,SSB1 homolog , heat shock protein\n of HSP70 family,Null mutant is viable, ssb1 ssb2 double dis\nruption mutants exhibit poor growth at all temperatures, but\n particularly at low temperatures; as well as hypersensitivi\nty to certain protein synthesis inhibitors, including aminog\nlycosides such as hygromycin B\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cell Cycle.alpha:Comprehensive identification of cell cycle-regulated genes o\nf the yeast Saccharomyces cerevisiae by microarray hybridiza\ntion. Mol Biol Cell. 1998 Dec;9(12):3273-97.\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPL24A:Homology to rat L24,ribosomal protein L24A (rp29) (YL21) (L3\n0A),Null mutant is viable.\n mRPL24B:Homology to rat L24,ribosomal protein L24B (rp29) (YL21) (L3\n0B),Null mutant is viable.\n mRPL17A:Homology to rat L17, human L17, and E. coli L22,ribosomal pr\notein L17A (L20A) (YL17),\n Cond467:steady_state_21_dec_C_ct-2\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n Cond445:Msn4_overexpression\n Cond454:YP_fructose_vs_reference_pool_car-2\n mRPS12:Homology to rat S12,ribosomal protein S12,\n Cond391:aa_starv_1_h\n mRPS15:Homology to rat S15 and E. coli S19,ribosomal protein S15 (S\n21) (rp52) (RIG protein),\n Cond814:Na+FK45'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Cond805:Ca/Ca+FK30'\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond677:DES459_(mec1)_-_log_phase_(IR_time_=_0_sample)\n Cond897:STATMMS\n Cond624:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y13-75\n Cond894:G2\n mRPS1A:Homologous to rat S3A,ribosomal protein S1A (rp10A),\n mRPS1B:Homologous to rat ribosomal protein S3A,ribosomal protein S1\nB (rp10B),\n Cond704:gal80-gal\n Cond395:Nitrogen_Depletion_30_min.\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond749: Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond694:gal10+gal\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond361:2.5mM_DTT_180_min_dtt-1\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond367:dtt_240_min_dtt-2\n Cond848:90_min\n mYLR413W:Unknown ,, Unknown\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond818:crz1/Na30'\n Cond378:1M_sorbitol_-_15_min\n Cond816:Na/Na+FK30'\n mRPL33B:Homology to rat L35a,ribosomal protein L33B (L37B) (rp47) (Y\nL37),Null mutant is viable.\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond874:30min\n mRPS3:Homology to mammalian S3,ribosomal protein S3 (rp13) (YS3),N\null mutant is inviable\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond374:1.5_mM_diamide_(50_min)\n mASC1:WD repeat protein (G-beta like protein) that interacts with \nthe translational machinery,G-beta like protein,Null mutant \nis viable. Null mutation suppresses the absence of growth of\n a cyp1- strain in anaerobiosis and also causes delayed grow\nth in aerobic or heme sufficient conditions; trp auxotrophs \nof the asc1 null allele are cold sensitive for growth; other\n mutants have increased cell size\n mRPS5:ribosomal small subunit protein homologous to mammalian S5 (\nhas approx. 70% identity with human, rat and hydrozoan S5). \nIt is the least basic of the non-acidic ribosomal proteins. \nIt is phosphorylated in yeast.,ribosomal protein S5 (S2) (rp\n14) (YS8),null is inviable; transcription of RPS5 is sensiti\nve to heat-shock and carbon source shift.\n Cond959:t2_g/r_ratio\n Cond809:Na30'\n mRPS31:Homology to rat S27a,ribosomal protein S31 (S37) (YS24),Null\n mutant is viable\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond905:(77i4)_S150-2B_YPGL+G__NormInt\n Cond366:dtt_120_min_dtt-2\n Cond970:swi1,_minimal_(c)\n Cond652:wt_plus_gamma_20_min\n Cond899:RPN4_MMS__\n Cond281:HMG2(tetpromoter)\n Cond396:Nitrogen_Depletion_1_h\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond658:DES460_(wt)_-_mock_irradiation_-_5_min\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n mRPL9A:Homology to rat L9,ribosomal protein L9A (L8A) (rp24) (YL11)\n,\n Cond654:wt_plus_gamma_45_min\n Cond363:dtt_015_min_dtt-2\n mRPS4A:Homology to rat S4 and human S4,ribosomal protein S4A (YS6) \n(rp5) (S7A),Null mutant is viable; rps4a rps4b double deleti\non is inviable\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPS4B:Homology to rat S4 and human S4,ribosomal protein S4B (YS6) \n(rp5) (S7B),\n Cond414:YPD_6_h_ypd-2\n Cond892:S\n Cond447:ethanol_vs._reference_pool_car-1\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond375:1.5_mM_diamide_(60_min)\n Cond967:swi1,_YPD_(c)\n Cond323:heat_shock_29_to_37,_20_minutes\n Cond733: Cond940:6h\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Cond531:GAL-PKC1-R398A,3hrs.gallog10(intensity)\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond961:t7_g/r_ratio\n Cond420:YPD_3_d_ypd-2\n Cond893:SMMS\n Cond340:constant_0.32_mM_H2O2_(60_min)_redo\n Cond379:1M_sorbitol_-_30_min\n Cond354:2.5mM_DTT_005_min_dtt-1\n Cond345:1_mM_Menadione_(10_min)redo\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond783:Peroxide_60'\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond895:G2MMS\n Cond878:MNNG\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond877:MMS\n Cond906:(77i5)_S150-2B_YPD_NormInt\n Cond417:YPD_12_h_ypd-2\n Cond946:W303ume6_YPD\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n mRPS6A:Homology to rat, mouse, and human S6,ribosomal protein S6A (\nS10A) (rp9) (YS4),\n Cond685:wt-gal\n Cond402:Nitrogen_Depletion_2_d\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond876:zero2\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond283:KAR2(tetpromoter)\n Cond360:2.5mM_DTT_120_min_dtt-1\n Cond885:20\n Cond984:pho85D_DMSO_24_hrs._vs._F82G_10_mM_1-Na_PP1_24_hrs._\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond699:gal4-gal\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n mFYV13:Function required for Yeast Viability on toxin exposure,,Nul\nl mutant is viable but exhibits K1 killer toxin hypersensiti\nvity.\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n mWRS1:W = IUPAC for tryptophan, RS = convention for aminoacyl-tRNA\n synthetases,tryptophan-tRNA ligase,Null mutant is inviable\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond421:YPD_5_d_ypd-2\n Cond858:pm71-30\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n mRPS7A:Homology to human S7 and Xenopus S8,ribosomal protein S7A (r\np30),Null mutant is viable\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mRPS7B:Homology to human S7 and Xenopus S8,ribosomal protein S7B (r\np30),\n
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Computational Genomics Lab, Tel-Aviv uniresity