Module number 1764




Database revision : gnsdb28.10
Date : Tue Feb 25 17:26:03 2003
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Cond626:DY1457_(wild_type)_3_mM_vs._61_nM_zinc_y13-121\n Cond663:mec1_plus_gamma_10_min\n mYNL010W:Unknown ,, Unknown\n Cond912:(99i1)_S150-2B_YPGL_NormInt\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n Cond399:Nitrogen_Depletion_8_h\n Cond432:YPD_stationary_phase_22_d_ypd-1\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n mRPS21B:Homology to rat S21,ribosomal protein S21B (S26B) (YS25),\n mURA5:Fifth step in pyrimidine biosynthesis pathway,orotate phosph\noribosyltransferase 1,Null mutant is viable\n Cond675:MHY1_(dun1)_+_heat_20_min\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond362:dtt_000_min__dtt-2\n Cond400:Nitrogen_Depletion_12_h\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond697:gal2-gal\n Cond467:steady_state_21_dec_C_ct-2\n Cond416:YPD_10_h__ypd-2\n mRPS29A:Homology to rat S29,ribosomal protein S29A (S36A) (YS29),\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond810:Na45'\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.NaNa:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond445:Msn4_overexpression\n Cond890:G1\n Cond:\n mRPS15:Homology to rat S15 and E. coli S19,ribosomal protein S15 (S\n21) (rp52) (RIG protein),\n Cond391:aa_starv_1_h\n Cond435:DBYmsn2-4-_37degree_heat_-_20_min\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond873:10min\n Cond805:Ca/Ca+FK30'\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond429:YPD_stationary_phase_5_d_ypd-1\n Cond318:37C_to_25C_shock_-_60_min\n mRPS22A:Homology to rat S15a,ribosomal protein S22A (S24A) (rp50) (Y\nS22),\n Cond897:STATMMS\n Cond624:DY1457_(wild_type)_3_mM_vs._10_uM_zinc_y13-75\n mRPS1A:Homologous to rat S3A,ribosomal protein S1A (rp10A),\n Cond894:G2\n Cond673:DES460_(wild_type)_+_heat_20_min\n Cond395:Nitrogen_Depletion_30_min.\n Cond704:gal80-gal\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond404:Nitrogen_Depletion_5_d\n Cond312:Heat_Shock_015_minutes_hs-2\n mSSZ1:DnaK homolog, interacts with Zuo1p (DnaJ homolog) to form a \nribosome-associated complex (RAC) that is bound to the ribos\nome via the Zuo1p subunit,HSP70 family,Null mutant is viable\n, cold sensitive; SSZ1 overexpression causes increased expre\nssion of some PDR genes\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n mRPL18A:Homology to rat ribosomal protein L18,ribosomal protein L18A\n (rp28A),\n mALG9:catalyzes the transfer of mannose from Dol-P-Man to lipid-li\nnked oligosaccharides,mannosyltransferase,accumulation of li\npid-linked Man6GlcNAc2; hypoglycosylation of secreted protei\nns\n Cond749: Cond689:gal3+gal\n Cond479:WT+/-100mM3AT(SetD)(R491)\n Cond693:gal7+gal\n Cond849:120_min\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond694:gal10+gal\n Cond430:YPD_stationary_phase_7_d_ypd-1\n Cond361:2.5mM_DTT_180_min_dtt-1\n Cond367:dtt_240_min_dtt-2\n Cond700:gal5-gal\n mTIF11:Translation initiation factor eIF1A,translation initiation f\nactor eIF1A,Null mutant is inviable\n mRPL7B:Homolog of mammalian ribosomal protein L7 and E. coli L30,ri\nbosomal protein L7B (L6B) (rp11) (YL8),Null mutant is viable\n; disruption of both RPL7A and RPL7B is lethal\n Cond879:MMC\n Cond313:Heat_Shock_030inutes__hs-2\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond481:WT+/-100mM3AT(SetB)(491)\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond818:crz1/Na30'\n mRPS23B:Homology to rat S23 and E. coli S12,ribosomal protein S23B (\nS28B) (rp37) (YS14),Null mutant is viable, rps23a rps23b dou\nble deletion mutants are inviable. Mutations in different pa\nrts of RPS23 have opposite affects on translational accuracy\n or antibiotic sensitivity.\n Cond378:1M_sorbitol_-_15_min\n mIMD4:similar to IMP dehydrogenase,IMP dehydrogenase homolog,\n Cond427:YPD_stationary_phase_2_d_ypd-1\n mSEC53:involved in synthesis of GDP-mannose and dolichol-phosphate-\nmannose; required for protein assembly in endoplasmic reticu\nlum,phosphomannomutase,null is inviable; ts mutant is defect\nive in glycosylation, accumulating inactive and incompletely\n glycosylated forms of secretory proteins within the ER lume\nn\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond816:Na/Na+FK30'\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n mRPL26B:Homology to rat L26,ribosomal protein L26B (L33B) (YL33),\n Cond653:wt_plus_gamma_30_min\n Cond687:gal1+gal\n mRPS3:Homology to mammalian S3,ribosomal protein S3 (rp13) (YS3),N\null mutant is inviable\n mRPS5:ribosomal small subunit protein homologous to mammalian S5 (\nhas approx. 70% identity with human, rat and hydrozoan S5). \nIt is the least basic of the non-acidic ribosomal proteins. \nIt is phosphorylated in yeast.,ribosomal protein S5 (S2) (rp\n14) (YS8),null is inviable; transcription of RPS5 is sensiti\nve to heat-shock and carbon source shift.\n Cond374:1.5_mM_diamide_(50_min)\n Cond433:YPD_stationary_phase_28_d_ypd-1\n Cond959:t2_g/r_ratio\n Cond809:Na30'\n Calcin.Ca/Ca:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond942:SK1ume6_YPD\n Cond965:ndt80_delete_mid_g/r_ratio_\n Cond905:(77i4)_S150-2B_YPGL+G__NormInt\n Cond366:dtt_120_min_dtt-2\n Cond881:4NQO\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond903:(77i2)_S150-2B_YPGL_NormInt\n Cond960:t5_g/r_ratio\n Cond627:DY1457_(wild_type)_3_mM_vs._76_nM_zinc_y12-122\n Cond639:DES460_+_0.02%_MMS_-_120_min\n mTIF1:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mTIF2:translation initiation factor eIF4A,translation initiation f\nactor eIF4A subunit,viable, tif1tif2 double mutant is lethal\n mTIF3:Suppressor of translation mutants,translation initiation fac\ntor eIF-4B,\n mTIF6:similar to human translation initiation factor 6 (eIF6); how\never, TIF6 does not act as a true translation initiation fac\ntor.The protein may be involved in the biogenesis and or sta\nbility of the 60S ribosomal subunits,,Null mutant is inviabl\ne; cells are depleted of 60S ribosomal subunits, translation\n initiation is inhibited, and cells arrest in G1\n mAPT1:Adenine phosphoribosyltransferase,adenine phosphoribosyltran\nsferase,\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n mRPL1A:Homology to rat L10a, eubacterial L1, and archaebacterial L1\n; identical to S. cerevisiae L1B (Ssm2p),ribosomal protein L\n1A, forms part of the 60S ribosomal subunit,Null mutant is v\niable; shows double mutant lethality with rpl1b (ssm2b) null\n mutants\n mRPL1B:Homology to rat L10a, eubacterial L1, and archaebacterial L1\n; identical to S. cerevisiae L1A (Ssm1p),ribosomal protein L\n1B,\n Cond652:wt_plus_gamma_20_min\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond899:RPN4_MMS__\n Cond397:Nitrogen_Depletion_2_h\n Cond281:HMG2(tetpromoter)\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond316:37C_to_25C_shock_-_30_min\n Cond305:Heat_Shock_40_minutes_hs-1\n Cond396:Nitrogen_Depletion_1_h\n Cond982:pho85D_10_mM_1NaPP1_\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond887:t-BuOOH\n mRPL9A:Homology to rat L9,ribosomal protein L9A (L8A) (rp24) (YL11)\n,\n mRPL13A:Homology to rat L13,ribosomal protein L13A,Null mutant is vi\nable.\n mRPL13B:Homology to rat L13,ribosomal protein L13B,\n Cond363:dtt_015_min_dtt-2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond941:SK1_YPD\n mYKL056C:Unknown ,, Unknown\n mRPS25A:Homology to rat S25,ribosomal protein S25A (S31A) (rp45) (YS\n23),\n mRPS25B:Homology to rat S25; belongs to the S25E family of ribosomal\n proteins,ribosomal protein S25B (S31B) (rp45) (YS23),\n mRPS4A:Homology to rat S4 and human S4,ribosomal protein S4A (YS6) \n(rp5) (S7A),Null mutant is viable; rps4a rps4b double deleti\non is inviable\n mRPS18B:Homology to rat S18 and E. coli S13,ribosomal protein S18B,\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond892:S\n Cond447:ethanol_vs._reference_pool_car-1\n Cond745: Cond967:swi1,_YPD_(c)\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond463:29_deg_growth_ct-1\n Cond323:heat_shock_29_to_37,_20_minutes\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond880:BCNU\n Stress.DTT1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond872:Zero1\n Cond940:6h\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond531:GAL-PKC1-R398A,3hrs.gallog10(intensity)\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n mRPL30:Homology to rat and mouse L30,ribosomal protein L30 (L32) (r\np73) (YL38) large subunit,Null mutant is inviable.\n mCAF20:binds to eIF4E, the mRNA cap-binding protein, and represses \ncap-dependent translation initiation by interfering with the\n interaction of eIF4E and eIF4G,20 kDa subunit , mRNA cap bi\nnding protein eIF-4F , 20 kDa subunit , mRNA cap binding pro\ntein eIF-4F,Null mutant is viable and grows faster; deletion\n of CAF20 partially suppresses mutations in translation init\niation factors; overexpression of CAF20 causes slower growth\n and enhances translation mutation phenotypes\n Cond934:8h\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond459:YP_sucrose_vs_reference_pool_car-2\n Cond961:t7_g/r_ratio\n Cond420:YPD_3_d_ypd-2\n Cond857:pm38-gtoe\n mRPL38:Homology to rat L38,ribosomal protein L38,\n Cond893:SMMS\n mRPS19A:Homology to rat S19,ribosomal protein S19A (S16aA) (rp55A) (\nYS16A),\n mRPL43A:Homology to human L37a,ribosomal protein L43A,\n mTOM7:Involved in mitochondrial protein import,translocase of the \nouter mitochondrial membrane,Null mutant is viable\n Cond379:1M_sorbitol_-_30_min\n Cond345:1_mM_Menadione_(10_min)redo\n Cond354:2.5mM_DTT_005_min_dtt-1\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond317:37C_to_25C_shock_-_45_min\n RapamycinDip.dip_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Cond434:DBY7286_37degree_heat_-_20_min\n UME6.ume6:The Ume6 regulon coordinates metabolic and meiotic gene expr\nession in yeast. Proc Natl Acad Sci U S A. 2002 Oct 15;99(2\n1):13431-6.\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond419:YPD_2_d_ypd-2\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond431:YPD_stationary_phase_13_d_ypd-1\n Cond783:Peroxide_60'\n mPUS7:Unknown ,, Unknown\n Cond878:MNNG\n Cond895:G2MMS\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond882:zero3\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond877:MMS\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n Cond640:DES459_(mec1-)_+_0.02%_MMS_-_5_min\n Cond875:60min\n Cond906:(77i5)_S150-2B_YPD_NormInt\n Cond417:YPD_12_h_ypd-2\n Cond946:W303ume6_YPD\n Cond886:g-ray\n mHPT1:enzyme involved in de novo purine biosynthesis,hypoxanthine \nguanine phosphoribosyltransferase,Null mutant is viable; mut\nants show resistance to 8-azaguanine\n Stress.Menadione:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond403:Nitrogen_Depletion_3_d\n Cond415:YPD_8_h_ypd-2\n Cond319:37C_to_25C_shock_-_90_min\n Cond685:wt-gal\n Cond402:Nitrogen_Depletion_2_d\n Cond811:Na60'\n Cond372:1.5_mM_diamide_(30_min)\n Cond876:zero2\n Calcin.crz1Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond732:fkh1,2_alpha_factor_000_min_y12n57\n Cond743: Cond401:Nitrogen_Depletion_1_d\n Cond885:20\n Cond411:diauxic_shift_timecourse_20.5_h\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n Cond453:YP_ethanol_vs_reference_pool_car-2\n mSUR4:Required for conversion of 24-carbon fatty acids to 26-carbo\nn species,,Null mutants is viable, not sensitive to UV or ga\nmma radiation. sur4 mutants suppress rad3, rvs161 delta, and\n rvs167 mutations. sur4 fen1 mutants and sur4 elo2 mutants a\nre inviable.\n zap1.Series0:Genome-wide characterization of the Zap1p zinc-responsive re\ngulon in yeast. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14)\n:7957-62.\n Cond274:yor080w(**3)\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mRPL16A:Homology to rat L13a,ribosomal protein L16A (L21A) (rp22) (Y\nL15),\n Cond421:YPD_5_d_ypd-2\n Y-Stre.Peroxide:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mRPL16B:Homology to rat ribosomal protein L13a,ribosomal protein L16\nB (L21B) (rp23) (YL15),\n Cond858:pm71-30\n mRPS28A:Homology to mammalian S28,ribosomal protein S28A (S33A) (YS2\n7),\n Cond671:DES459_(mec1)_-_mock_irradiation_-_30_min\n Cond307:Heat_Shock_80_minutes_hs-1\n Cond428:YPD_stationary_phase_3_d_ypd-1\n Cond304:Heat_Shock_30_minutes_hs-1\n fkh1,2sf.Series0:Two yeast forkhead genes regulate the cell cycle and pseudoh\nyphal growth. Nature. 2000 Jul 6;406(6791):90-4.\n Stress.tempsteady:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond884:10\n Cond703:gal10-gal\n Cond436:DBYmsn2/4_(real_strain)_+_37degrees_(20_min)\n Cond958:t0.5_g/r_ratio\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity