Module number 1692




Database revision : gnsdb28.10
Date : Tue Feb 25 17:26:06 2003
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Cond292:Glucosamine\n Cond102:mrt4\n Cond248:ymr030w\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts.  Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond130:rml2(**13)\n mSEC31:involved in protein transport from endoplasmic reticulum to \nGolgi,COPII coat of secretory pathway vesicles component (p1\n50),Null mutant is inviable\n mPDC1:pyruvate decarboxylase,pyruvate decarboxylase,undetectable p\nyruvate decarboxylase activity in pdc1pdc5 double mutants\n Cond93:kre1\n Cond280:FKS1(tetpromoter)\n Cond185:ubr2\n mWWM1:Unknown ,, Unknown\n Cond140:rps24a(**9)\n mSCS2:Likely to be involved in regulating INO1 expression, suppres\nsor of a dominant nuclear mutation that is inositol-dependen\nt in the presence of choline,,Null mutant is viable but is a\nn inositol auxotroph above 34 deg.\n Cond105:nrf1\n Cond28:cla4(haploid)\n Cond81:hog1(haploid)\n Cond940:6h\n Cond:\n mRRD1:Resistant to Rapamycin Deletion,,Null mutant is viable but s\nhows pleiotropic phenotypes (eg. caffeine and rapamycin resi\nstance, vanadate and calcium sensitivity, etc.); synthetic l\nethal with RRD2 (YPL152w)\n mTHR1:homoserine kinase,homoserine kinase,Null mutant is viable, t\nhreonine auxotroph\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles.  Science. 200\n0 Feb 4;287(5454):873-80\n Cond210:yer002w\n Cond200:yel001c\n Cond245:ymr014w\n Cond285:RHO1(tetpromoter)\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond61:fks1(haploid)\n mERV46:ER vesicle protein of 46 kDa,ER-Golgi transport vesicle prot\nein,Null mutant is viable but cold sensitive.\n mRET2:coatomer (COPI) complex delta subunit,,ret2-1 mutant is ther\nmosensitive and shows defects in retrieval of dilysine-tagge\nd proteins from the Golgi back to the ER and, at the non-per\nmissive temperature, in forward ER-to-Golgi transport\n Cond273:yor078w\n Cond287:2-deoxy-D-glucose\n Cond717:t2-SSD1\n mNAF1:Unknown ,, Unknown\n mOXA1:Mediates the export of proteins from the mitchondrial matrix\n to the intermembrane space. ,,Null mutant is viable but is \nrespiratory-deficient and lacks cytochrome oxidase activity;\n oxa1 mutant can be complemented by human OXA1; multicopy OX\nA1 suppresses afg3 and rca1 mutants\n Cond145:rts1\n Cond139:rpl8a\n Cond43:dot4\n mVRP1:Involved in cytoskeletal organization and cellular growth,pr\noline-rich protein verprolin,Null mutant is viable but is bo\nth temperature and pH sensitive and cannot grow on minimal m\nedium. Null mutant also exhibits depolarization of the actin\n cytoskeleton.\n mSRV2:70-kDa adenylyl cyclase-associated protein,70 kDa adenylyl c\nyclase-associated protein,Null mutant is inviable.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYIL041W:Unknown ,, Unknown\n mRNQ1:Rich in asparagine (N) and glutamine (Q),transferable epigen\netic modifier,\n Cond134:rpl12a\n Cond58:erp2\n Cond256:ymr141c\n Cond52:erd1\n mYHR218W:Unknown ,, Unknown\n Cond26:cka2\n mIMP2':Protein involved in nucleo-mitochondrial control of maltose,\n galactose and raffinose utilization,transcription factor,Nu\nll mutant is viable, Inability to grow on maltose, galactose\n and raffinose in respiratory-deficient conditions or in the\n presence of ethidium bromide and erythromycin; leaky phenot\nype on oxidizable carbon sources: sensitivity to heat shock \nand sporulation deficiency\n mSTI1:Heat shock protein also induced by canavanine and entry into\n stationary phase,heat shock protein also induced by canavan\nine and entry into stationary phase,Null mutant is viable bu\nt shows slow growth at high or low temperatures; shows synth\netic interactions with hsp82, cpr7, kin28 and sba1\n mADE3:Required for the biosynthesis of purines, thymidylate, methi\nonine, histidine, pantothenic acid and formylmethionyl-tRNA,\nC1-tetrahydrofolate synthase,Null mutant is viable, adenine \nauxotroph, histidine auxotroph\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond712:t4+SSD1\n Cond205:yel033w\n mPAN1:Involved in actin organization and endocytosis,,Null mutant \nis inviable; conditional mutants show arrest of translation \ninitiation, alterations in mRNA poly(A) tail lengths, and al\ntered cellular location of Mod5p\n Cond284:PMA1(tetpromoter)\n mYBR261C:Unknown ,, Unknown\n mPIB2:Phosphatidylinositol 3-phosphate binding,,\n Cond91:kim4\n mNCP1:NADP-cytochrome P450 reductase,NADP-cytochrome P450 reductas\ne,Null mutant is viable\n mFAS2:Trifunctional enzyme,fatty acid synthase alpha subunit,Fatty\n acid synthetase deficient\n mSED1:putative cell surface glycoprotein,cell surface glycoprotein\n (putative),Null mutant is viable; during stationary phase, \nnull mutants exhibit increased sensitivity to Zymolyase.\n Cond283:KAR2(tetpromoter)\n mRSC6:a subunit of RSC, a fifteen-protein chromatin remodeling com\nplex and related to the swi/snf complex.,,Null mutant is inv\niable\n Cond103:msu1\n mTUP1:general repressor of transcription (with Cyc8p); mediates gl\nucose repression,glucose repression regulatory protein, exhi\nbits similarity to beta subunits of G proteins,Null mutant i\ns viable; exhibits flocculent colony morphology\n mWTM1:WD repeat containing transcriptional modulator 1,transcripti\nonal modulator,Null mutant is viable\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n mPIN3:[PSI+] induction,,Other phenotypes: overexpression of PIN3 a\nllows for the induction of the [PSI+] prion in strains cured\n of [PIN+].\n mLCB1:Involved in sphingolipid biosynthesis; may catalyze the firs\nt step in biosynthesis of long-chain sphingolipids,serine pa\nlmitoyltransferase component (putative),Null mutant is viabl\ne; auxotrophic for long-chain component of sphingolipids; ho\nmozygous lcb1 diploids fail to sporulate\n Cond521:fus3-K42Dą50nMaF,30minlog10(intensity)\n mYEL043W:Unknown ,, Unknown\n Cond939:4h\n

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Computational Genomics Lab, Tel-Aviv uniresity