Module number 1657




Database revision : gnsdb28.10
Date : Tue Feb 25 17:19:30 2003
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mTOM37:Translocase of the Outer Mitochondrial membrane,heterodimeri\nzes with Tom70p, preferentially recognizes the mature region\ns of precursor proteins associated with ATP-dependent cytoso\nlic chaperones , mitochondrial import receptor protein , het\nerodimerizes with Tom70p, preferentially recognizes the matu\nre regions of precursor proteins associated with ATP-depende\nnt cytosolic chaperones , mitochondrial import receptor prot\nein,Null mutant is viable, temperature-sensitive for respira\ntion driven growth, fails to import precursors into isolated\n mitochondria, exhibits double mutant inviability with strai\nns deleted for TOM70 or TOM20.\n mSPS1:dispensable for mitosis, involved in middle/late stage of me\niosis, required for spore wall formation,,Null mutant is via\nble\n Cond936:12h\n Cond206:yel044w\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond918:1h\n mSEC15:Protein involved in vesicle traffic between Golgi and plasma\n membrane. The Exocyst complex is required for exocytosis.,e\nxocyst complex 113kDa component,The sec15-1 allele exhibits \ntemperature-sensitive growth and defects in the secretory pa\nthway.\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n mYLR164W:Unknown ,, Unknown\n mGIM4:Prefoldin subunit 2; putative homolog of subunit 2 of bovine\n prefoldin, a chaperone comprised of six subunits,bovine pre\nfoldin subunit 2 homolog (putative),Null mutant is viable, s\nensitive to anti-microtubule drugs benomyl and nocadazole; s\nynthetically lethal with tub4-1 mutations\n Cond934:8h\n Cond920:3h\n mYMR034C:Unknown ,, Unknown\n Cond695:gal80+gal\n mCLB6:role in DNA replication during S phase,B-type cyclin,Null mu\ntant is viable\n Cond9:ard1\n Cond938:2h\n mYGR161C:Unknown ,, Unknown\n mGRE1:Induced by osmotic stress,,Null mutant is viable and shows n\no phenotype in osmotic, ionic or oxidative stress\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYMR118C:Unknown ,, Unknown\n mIES6:Ino Eighty Subunit 6,,Null: non essential.\n mMSI1:chromatin assembly complex, subunit 3: Encodes the smallest \n(p50) subunit of the yeast Chromatin Assembly Factor-I (CAF-\nI) involved in DNA-replication-linked nucleosome assembly. H\nomologous to the small subunit of the Human CAF-I.,chromatin\n assembly factor-I (CAF-I) p50 subunit , negative regulator \nof ras-mediated cAMP induction , similar to GTP-binding prot\nein beta subunit,Null mutant is viable, UV irradiation sensi\ntive; associated with decreased silencing of telomere-adjace\nnt genes. MSI1 is a multicopy suppressor of high cAMP, sporu\nlation defects, and heat shock sensitivity in ira1 and RASva\nl19 mutants\n mCPR2:Human cyclophilin B protein,cyclophilin , peptidyl-prolyl ci\ns-trans isomerase (PPIase),Null mutant is viable; sensitive \nto heat\n Cond939:4h\n
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Computational Genomics Lab, Tel-Aviv uniresity