Module number 1629




Database revision : gnsdb28.10
Date : Tue Feb 25 17:15:17 2003
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Cond330:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_15_minutes\n Cond72:gpa2\n mRHB1:rheb-like suppressor of growth,GTP-binding protein , ras fam\nily,Mutant exhibits shortened lag phase, failure to arrest i\nn stationary phase; overexpression causes delayed growth.\n Cond826:tlc1_Expt.1_Passage_7\n Cond141:rps24a(haploid)\n Cond476:GCN4C/GCN4(R4760/R6257)\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mTFS1:(putative) lipid binding protein; supressor of a cdc25 mutat\nion,lipid binding protein (putative) , supressor of a cdc25 \nmutation,Null mutant is viable.\n Cond104:npr2\n Cond388:Hypo-osmotic_shock_-_60_min\n Pho85.pho85:Chemical inhibition of the Pho85 cyclin-dependent kinase rev\neals a role in the environmental stress response. Proc Natl\n Acad Sci U S A. 2001 Oct 23;98(22):12578-83.\n Cond410:diauxic_shift_timecourse_18.5_h\n Cond302:Heat_Shock_15_minutes_hs-1\n Cond418:YPD_1_d_ypd-2\n Cond675:MHY1_(dun1)_+_heat_20_min\n Cond13:ase1(**12)\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n Cond981:F82G_pho4D_10_mM_1NaPP1\n Cond362:dtt_000_min__dtt-2\n Cond513:GAL-STE11-4,3hrs.gallog10(intensity)\n Stress.diamide:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond425:YPD_stationary_phase_12_h_ypd-1\n Cond674:DES459_(mec1)_+_heat_20_min\n Cond810:Na45'\n Cond911:(83i5)_S150-2B_YPD_NormInt\n Stress.Carbon:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mTSL1:123 kD regulatory subunit of trehalose-6-phosphate synthase/\nphosphatase complex; homologous to TPS3 gene product,similar\n to TPS3 gene product , trehalose-6-phosphate synthase/phosp\nhatase complex 123 kDa regulatory subunit,Null mutant is via\nble\n Cond364:dtt_030_min__dtt-2\n Cond373:1.5_mM_diamide_(40_min)\n Cond454:YP_fructose_vs_reference_pool_car-2\n Cond445:Msn4_overexpression\n Cond822:tlc1_Expt.1_Passage_3\n Cond409:diauxic_shift_timecourse_15.5_h\n mGAD1:glutamate decarboxylase,glutamate decarboxylase,\n Cond802:CaFK30'\n Cond142:rps27b(**11)\n Cond300:Heat_Shock_05_minutes_hs-1\n Cond439:DBY7286_+_0.3_mM_H2O2_(20_min)\n Cond814:Na+FK45'\n Cond310:Heat_Shock_000_minutes_hs-2\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond166:ste11(haploid)\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond318:37C_to_25C_shock_-_60_min\n Cond673:DES460_(wild_type)_+_heat_20_min\n TorRama.Series0:Partitioning the transcriptional program induced by rapamyci\nn among the effectors of the Tor proteins. Curr Biol. 2000 D\nec 14-28;10(24):1574-81\n Cond312:Heat_Shock_015_minutes_hs-2\n Cond683:MHY1_(crt1)_vs._CRY1_(wild_type)_-_log_phase\n Cond59:erp4\n Cond306:Heat_Shock_60_minutes_hs-1\n Cond851:15_min\n Cond367:dtt_240_min_dtt-2\n tcl1.tcl1:The genome-wide expression response to telomerase deletion i\nn Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 \nJul 9;99(14):9316-21.\n Cond187:vac8\n Stress.Heat1:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.Heat2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond385:Hypo-osmotic_shock_-_15_min\n mPAU7:similar to Pau3, member of Pau1 family,,\n Cond972:anc1\n mGLK1:Glucose phosphorylation,glucokinase,Null mutant is viable wi\nth no discernible difference from wild-type; hxk1, hxk2, glk\n1 triple null mutants are unable to grow on any sugar except\n galactose and fail to sporulate\n Cond662:mec1_plus_gamma_5_min\n Cond26:cka2\n Cond16:bni1(haploid)\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond443:DBYyap1_+_0.32_mM_H2O2_(20_min)\n Cond874:30min\n Cond314:Heat_Shock_060_minutes__hs-2\n Cond687:gal1+gal\n Cond27:ckb2\n Cond374:1.5_mM_diamide_(50_min)\n Cond691:gal5+gal\n Cond370:1.5_mM_diamide_(10_min)\n SSD1.ANC1: Cond230:yhr022c\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n Cond778:msn2/4_acid_10'\n Cond325:29C_to_33C_-_5_minutes\n Cond809:Na30'\n Cond282:IDI1(tetpromoter)\n Stress.ColdShock:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond177:swi6(haploid)\n Cond859:ms221-30\n Cond828:tlc1_Expt.1_Passage_9\n Cond813:Na+FK30'\n Cond303:Heat_Shock_20_minutes_hs-1\n Cond650:wt_plus_gamma_5_min\n Cond408:diauxic_shift_timecourse_13.5_h\n mGPH1:Releases glucose-1-phosphate from glycogen,glycogen phosphor\nylase,Null mutant is viable; haploid cells contain higher le\nvels of intracellular glycogen\n Cond160:sir4\n Cond438:DBYyap1_+_37degree_heat_(repeat)\n Cond837:tlc1_Expt.2_Passage_9__\n Cond40:dig1,dig2\n Cond526:ste11D/wtlog10(intensity)\n Stress.dshift:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond332:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_5_minutes\n Cond390:aa_starv_0.5_h\n Cond320:heat_shock_17_to_37,_20_minutes\n Cond836:tlc1_Expt.2_Passage_8\n Cond316:37C_to_25C_shock_-_30_min\n Cond136:rpl27a(**4)\n Cond305:Heat_Shock_40_minutes_hs-1\n mYJL215C:Unknown ,, Unknown\n RapamycinHap.hap_ram:Rapamycin-modulated transcription defines the subset of nutr\nient-sensitive signaling pathways directly controlled by the\n Tor proteins. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26)\n:14866-70.\n Cond301:Heat_Shock_10_minutes_hs-1\n Cond45:ecm1(**3)\n Calcin.CaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond369:1.5_mM_diamide_(5_min)\n mPGM2:Phosphoglucomutase,phosphoglucomutase,Null mutant is viable,\n pgm1 pgm2 deletion mutants fail to grow on galactose\n Cond487:pho80_vs_WT\n mMSC1:Meiotic Sister-Chromatid recombination,,\n mHSP12:induced by heat shock, entry into stationary phase, depletio\nn of glucose, and addition of lipids (fatty acids),heat shoc\nk protein 12,Null mutant is viable, but shows induction of h\neat shock response under conditions normally associated with\n low-level HSP12 expression\n Cond363:dtt_015_min_dtt-2\n Cond337:constant_0.32_mM_H2O2_(30_min)_redo\n Cond800:CaFK5'\n Cond190:vps8\n Y-Stre.msn2/4acid:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Stress.YPD:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond414:YPD_6_h_ypd-2\n Cond19:bub3(**2,8,13)\n Cond386:Hypo-osmotic_shock_-_30_min\n Stress.YPDStat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond371:1.5_mM_diamide_(20_min)\n Cond463:29_deg_growth_ct-1\n Cond323:heat_shock_29_to_37,_20_minutes\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond651:wt_plus_gamma_10_min\n Stress.DTT2:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond832:tlc1_Expt.2_Passage_4\n Cond326:29C_to_33C_-_15_minutes\n mYOR135C:Unknown ,, Unknown\n Cond855:pm38-30\n Cond426:YPD_stationary_phase_1_d_ypd-1\n Cond344:constant_0.32_mM_H2O2_(160_min)_redo\n mYHL018W:Unknown ,, Unknown\n Cond437:DBYyap1-_37degree_heat_-_20_min_(redo)\n Stress.WeakHeat:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond322:heat_shock_25_to_37,_20_minutes\n Cond111:pcl6\n Cond705:gal1gal10+gal\n Cond459:YP_sucrose_vs_reference_pool_car-2\n mIMG2:required for integrity of mitochondrial genome,,Null mutant \nis viable but shows respiratory deficiency and loss of wild-\ntype mtDNA: conversion to rho- and rho zero petites\n Cond180:top1(haploid)\n Cond827:tlc1_Expt.1_Passage_8\n mGLN1:glutamine synthetase,glutamine synthetase,Glutamine syntheta\nse non-derepressible\n mHSP26:heat shock protein 26,heat shock protein 26,Null mutant is v\niable; hsp26 hsp42 double deletion mutants are viable\n Cond379:1M_sorbitol_-_30_min\n Cond387:Hypo-osmotic_shock_-_45_min\n Cond449:glucose_vs._reference_pool_car-1\n mHXK1:Glucose phosphorylation,hexokinase I (PI) (also called hexok\ninase A),Null mutant is viable, is able to ferment fructose,\n and has little or no effect on glucose repression; hxk1, hx\nk2 double null mutant cannot ferment fructose and fails to s\nhow glucose repression at SUC2, CYC1, GAL10\n Cond151:sbp1\n Cond444:Msn2_overexpression_(repeat)\n Cond758:Heat_0'_(A)\n Cond317:37C_to_25C_shock_-_45_min\n Cond87:isw1\n Cond434:DBY7286_37degree_heat_-_20_min\n Stress.HeatSorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.H202:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond478:WT+/-10mM3AT(R491)\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n Cond321:heat_shock_21_to_37,_20_minutes\n Cond144:rtg1\n mACO1:Aconitase, mitochondrial,aconitase,glutamate auxotrophy\n Cond333:29C_+1M_sorbitol_to_33C_+_*NO_sorbitol_-_15_minutes\n Cond329:29C_+1M_sorbitol_to_33C_+_1M_sorbitol_-_5_minutes\n mSPI1:Stationary Phase Induced; strongly expressed during stationa\nry phase, and trancription is dependent on MSN2/MSN4.,,\n Cond456:YP_glucose_vs_reference_pool_car-2\n Cond835:tlc1_Expt.2_Passage_7\n mYKL036C:Unknown ,, Unknown\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond132:rnr1(haploid**9)\n mSOL4:similar to SOL3,,\n Cond171:ste24(haploid)\n Cond62:fpr1\n mYGP1:may be involved in cellular adaptations prior to stationary \nphase,gp37, a glycoprotein synthesized in response to nutrie\nnt limitation which is homologous to the sporulation-specifi\nc SPS100 gene,\n Cond342:constant_0.32_mM_H2O2_(100_min)_redo\n Cond779:msn2/4_acid_20'\n Stress.Sorbitol:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond319:37C_to_25C_shock_-_90_min\n Cond811:Na60'\n mYHR087W:Unknown ,, Unknown\n Cond372:1.5_mM_diamide_(30_min)\n Cond667:mec1_plus_gamma_60_min\n Stress.tempgrow:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Stress.HeatVar:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond324:heat_shock_33_to_37,_20_minutes\n mTPS1:Probable regulator of glucose influx into the cell & into gl\nycolytic pathway, indirectly regulating glucose-induced sign\nalling (activation & inactivation) & initial step(s) of gluc\nose metabolism. Homologue of E. coli otsA protein,trehalose-\n6-phosphate synthase/phosphatase complex 56 kDa synthase sub\nunit,null is viable, but does not grow on glucose and/or fru\nctose,and shows lack of trehalose\n mTPS2:Trehalose-6-phosphate phosphatase,trehalose-6-phosphate phos\nphatase,Null mutant is viable, exhibits complete loss of tre\nhalose-6-phosphate phosphatase activity, measured in vitro, \nand accumulation of excessive amounts of trehalose-6-phospha\nte instead of trehalose upon heat shock or entrance into sta\ntionary phase in vivo; null mutant is temperature sensitive,\n tps2 (pfk3) pfk1 double mutants are glucose negative\n pho.Pho:New components of a system for phosphate accumulation and po\nlyphosphate metabolism in Saccharomyces cerevisiae revealed \nby genomic expression analysis. Mol Biol Cell. 2000 Dec;11(\n12):4309-21.\n mGSY2:Highly similar to GSY1. GSY2 is the predominantly expressed \nglycogen synthase. Activity is probably regulated by cAMP-de\npendent and SNF1 protein kinases and type 1 phosphatase,glyc\nogen synthase (UDP-glucose-starch glucosyltransferase),Null \nmutant is viable. Mutant lacking both GSY1 and GSY2 is viabl\ne but lacks glycogen synthase activity and glycogen depositi\non\n Cond380:1M_sorbitol_-_45_min_\n Cond84:hst3\n Cond55:erg4(haploid**7)\n Stress.Various:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond51:eft2\n Cond831:tlc1_Expt.2_Passage_3\n mPNC1:pyrazinamidase and nicotinamidase,nicotinamidase , pyrazinam\nidase,Null mutant is viable\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond815:Na+FK60'\n mSTF2:ATPase stabilizing factor,ATPase stabilizing factor,\n Cond442:DBYyap1-_+_0.3_mM_H2O2_(20_min)\n Cond339:constant_0.32_mM_H2O2_(50_min)_redo\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Calcin.NaFK:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n Cond858:pm71-30\n mYGR073C:Unknown ,, Unknown\n Cond307:Heat_Shock_80_minutes_hs-1\n Cond514:GAL-STE12,3hrs.gallog10(intensity)\n Cond304:Heat_Shock_30_minutes_hs-1\n mTPS1 mTPS2 mTSL1
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Computational Genomics Lab, Tel-Aviv uniresity