Module number 1523




Database revision : gnsdb28.10
Date : Tue Feb 25 17:10:56 2003
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Cond158:sir2\n mHIS4:histidinol dehydrogenase,histidinol dehydrogenase,Null mutan\nt is viable and requires histidine\n Cond217:yer050c\n Cond277:AUR1(tetpromoter)\n Cond698:gal3-gal\n Cond476:GCN4C/GCN4(R4760/R6257)\n mHIS7:glutamine amidotransferase:cyclase, also called imidazole gl\nycerol phosphate synthase,glutamine amidotransferase:cyclase\n , imidazole glycerol phosphate synthase (synonym),Null muta\nnt is viable and requires histidine\n Cond221:yer083c\n Cond104:npr2\n mYLR179C:Unknown ,, Unknown\n Cond95:mac1\n Cond13:ase1(**12)\n Cond121:qcr2(haploid)\n Cond730:hda1\n Cond185:ubr2\n Stress.HypoOsmot:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n mMNN1:Alpha-1,3-mannosyltransferase,alpha-1,3-mannosyltransferase,\nNull mutant is viable\n Cond244:ymr010w\n mSUL2:Sulfate uptake,high affinity sulfate permease,\n mOAC1:oxaloacetate carrier,oxaloacetate transport protein,\n Cond702:gal7-gal\n Cond391:aa_starv_1_h\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond393:aa_starv_4_h\n Mating.Mating:Signaling and circuitry of multiple MAPK pathways revealed b\ny a matrix of global gene expression profiles. Science. 200\n0 Feb 4;287(5454):873-80\n Stress.aa_starv:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond245:ymr014w\n Cond480:WT+/-100mM3AT(SetA)(R491)\n Cond184:ubr1\n Cond123:rad57\n Cond395:Nitrogen_Depletion_30_min.\n Cond279:ERG11(tetpromoter)\n Cond701:gal6-gal\n Cond247:ymr029c\n Cond61:fks1(haploid)\n mPHO8:repressible alkaline phosphatase,repressible alkaline phosph\natase,phosphatase deficient\n Cond216:yer044c(haploid)\n Cond693:gal7+gal\n Cond226:yhl029c\n Cond194:yap1\n mADH5:alcohol dehydrogenase isoenzyme V,alcohol dehydrogenase isoe\nnzyme V,\n mGAT2:Product of gene unknown,,\n mTRP4:anthranilate phosphoribosyl transferase,anthranilate phospho\nribosyl transferase,tryptophan requiring\n Cond145:rts1\n mSNZ1:Snooze: stationary phase-induced gene family; may be involve\nd in cellular response to nutrient limitation and growth arr\nest,highly conserved 35 kDa protein that shows increased exp\nression after entry into stationary phase,Null mutant is via\nble, sensitive to 6-azauracil and methylene blue.\n Cond481:WT+/-100mM3AT(SetB)(491)\n Cond54:erg3(haploid)\n Cond385:Hypo-osmotic_shock_-_15_min\n mIMD1:IMP dehydrogenase homolog,IMP dehydrogenase homolog,\n Cond68:gas1\n Cond116:pex12\n Cond20:bub3(haploid**2)\n Cond512:GAL-STE5-CTM,3hrs.gallog10(intensity)\n Cond26:cka2\n Cond9:ard1\n mILV6:acetolactate synthase regulatory subunit,,\n gala.-gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond69:gcn4\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond205:yel033w\n Cond91:kim4\n Cond27:ckb2\n Cond394:aa_starv_6_h\n Cond73:gyp1\n mECM17:ExtraCellular Mutant,sulfite reductase (putative),loss of fu\nnction mutants are methionine requiring and sensitive to the\n cell wall perturbing agent calcoflour white.\n Cond162:spf1\n Cond230:yhr022c\n Cond475:0.5x/1xAA(MildLeu,HisStarvation)(R176)\n mZRT1:High-affinity zinc transport protein,,disruption viable\n Cond25:cin5\n mRIB5:Riboflavin biosynthesis,,Null mutant is viable, exhibits rib\noflavin auxotrophy\n mMET3:ATP sulfurylase,ATP sulfurylase,Null mutant is viable, and i\ns a methionine auxotroph\n mYGL117W:Unknown ,, Unknown\n mMET6:vitamin B12-(cobalamin)-independent isozyme of methionine sy\nnthase (also called N5-methyltetrahydrofolate homocysteine m\nethyltransferase or 5-methyltetrahydropteroyl triglutamate h\nomocysteine methyltransferase),vitamin B12-(cobalamin)-indep\nendent isozyme of methionine synthase (also called N5-methyl\ntetrahydrofolate homocysteine methyltransferase or 5-methylt\netrahydropteroyl triglutamate homocysteine methyltransferase\n),Null mutant is viable, and is a methionine auxotroph\n mYOR271C:Unknown ,, Unknown\n Chromo.chromo:Genomewide studies of histone deacetylase function in yeast.\n Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13708-13.\n Cond39:dig1\n Cond135:rpl20a\n mCPA2:carbamyl phosphate synthetase,carbamyl phosphate synthetase,\nNull mutant is viable\n Cond11:arg5,6\n Cond477:GCN4/gcn4Din100mM3AT(KNY164/KNY124)\n Cond101:mrpl33\n Cond397:Nitrogen_Depletion_2_h\n Cond102:mrt4\n Cond390:aa_starv_0.5_h\n Cond3:aep2\n mARG1:arginosuccinate synthetase,arginosuccinate synthetase,Argini\nne requiring\n Cond225:yhl013c\n Cond396:Nitrogen_Depletion_1_h\n mARG3:Sixth step in arginine biosynthesis,ornithine carbamoyltrans\nferase,Arginine requiring\n mSAM2:methionine biosynthesis regulation,,Null mutant is viable\n mARG4:argininosuccinate lyase,argininosuccinate lyase,Arginine req\nuiring\n mSAM3:S-adenosylMethionine Permease,high affinity S-adenosylmethio\nnine permease,Null mutant is viable but has inability to use\n S-adenosylmethionine as a sulfur source\n mSTR2:Sulfur TRansfer,cystathionine gamma-synthase,Null mutant is \nviable but unable to turn cysteine into homocysteine. Grows \nwhen supplied with cystathionine.\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond29:clb2\n Cond130:rml2(**13)\n mARG5,6:N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutam\nate kinase,N-acetyl-gamma-glutamyl-phosphate reductase and a\ncetylglutamate kinase,Arginine requiring\n Cond647:dun1-_+_0.02%_MMs_-_30_min\n Cond190:vps8\n mARO3:DAHP synthase; a.k.a. phospho-2-dehydro-3-deoxyheptonate ald\nolase, phenylalanine-inhibited; phospho-2-keto-3-deoxyhepton\nate aldolase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-\ndeoxy-D-arabine-heptulosonate-7-phosphate synthase,DAHP synt\nhase; a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, ph\nenylalanine-inhibited; phospho-2-keto-3-deoxyheptonate aldol\nase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-deoxy-D-a\nrabine-heptulosonate-7-phosphate synthase,null mutant is via\nble\n Cond140:rps24a(**9)\n Cond19:bub3(**2,8,13)\n Cond112:pep12\n Cond90:jnm1\n Cond967:swi1,_YPD_(c)\n GCN4.gcn4:Transcriptional profiling shows that Gcn4p is a master regul\nator of gene expression during amino acid starvation in yeas\nt. Mol Cell Biol. 2001 Jul;21(13):4347-68.\n Cond384:Hypo-osmotic_shock_-_5_min\n Cond53:erg2\n Cond6:anp1\n Cond298:Terbinafine\n mDPL1:dihydrosphingosine phosphate lyase (also known as sphingosin\ne phosphate lyase),dihydrosphingosine phosphate lyase (also \nknown as sphingosine phosphate lyase),Null mutant is viable \nbut is sensitive to exogenous D- erythro-sphingosine and phy\ntosphingosine and accumulates sphingosine 1-phosphate upon e\nxposure to exogenous sphingosine; overexpression confers res\nistance to sphingosine\n Cond78:hir2\n COMP.CH:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond201:yel008w\n Cond229:yhr011w(**14)\n mOPI3:Second and third steps of methylation pathway for phosphatid\nylcholine biosynthesis,methylene-fatty-acyl-phospholipid syn\nthase (unsaturated phospholipid N-methyltransferase),Null mu\ntant is viable, temperature sensitive in the presence of mon\nomethylethanolamine, exhibits an inositol secretion phenotyp\ne\n Cond271:yor051c(**14)\n mMET10:subunit of assimilatory sulfite reductase,assimilatory sulfi\nte reductase subunit,Null mutant is viable, and is a methion\nine auxotroph\n Cond176:swi5\n mECM40:ExtraCellular Mutant,acetylornithine acetyltransferase,A Tn3\n insertion into this gene causes hypersensitivity to the cel\nl surface polymer perturbing agent calcofluor white.\n Stress.NitroDepl:Genomic expression programs in the response of yeast cells t\no environmental changes. Mol Biol Cell. 2000 Dec;11(12):424\n1-57\n Cond273:yor078w\n Cond287:2-deoxy-D-glucose\n mMET14:adenylylsulfate kinase,adenylylsulfate kinase,Null mutant is\n viable, and is a methionine auxotroph\n Cond48:ecm29\n mMET16:3'phosphoadenylylsulfate reductase,3'phosphoadenylylsulfate \nreductase,Null mutant is viable, and is a methionine auxotro\nph\n Cond478:WT+/-10mM3AT(R491)\n mMET17:O-Acetylhomoserine-O-Acetylserine Sulfhydralase,O-acetylhomo\nserine (thiol)-lyase,Null mutant is viable, methionine auxot\nroph, becomes darkly pigmented in the presence of Pb2+ ions;\n resistant to methylmercury and exhibits increased levels of\n H2S\n Cond128:rgt1\n mLEU1:leucine biosynthesis,isopropylmalate isomerase,Leucine requi\nring\n Cond144:rtg1\n Cond150:sbh2\n SwiSnf.swisnf:Whole-genome expression analysis of snf/swi mutants of Sacch\naromyces cerevisiae. Proc Natl Acad Sci U S A. 2000 Mar 28;\n97(7):3364-9.\n Cond47:ecm18(**7)\n Cond139:rpl8a\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n gala.+gal:Integrated genomic and proteomic analyses of a systematicall\ny perturbed metabolic network. Science. 2001 May 4;292(5518\n):929-34.\n Cond24:cem1\n Sporulation.Series0:The transcriptional program of sporulation in budding yeast.\n Science. 1998 Oct 23;282(5389):699-705.\n mALD5:Utilizes NADP+ as the preferred coenzyme. Activated by K+.,a\nldehyde dehydrogenase,\n Cond134:rpl12a\n Cond171:ste24(haploid)\n mYHM1:high copy suppressor of abf2 lacking the HMG1-like mitochond\nrial HM protein; putative mitochondrial carrier protein,,Nul\nl mutant is viable; shm1 abf2 double deletion cannot grow on\n glycerol\n Cond175:swi4\n mADE3:Required for the biosynthesis of purines, thymidylate, methi\nonine, histidine, pantothenic acid and formylmethionyl-tRNA,\nC1-tetrahydrofolate synthase,Null mutant is viable, adenine \nauxotroph, histidine auxotroph\n Cond250:ymr031w-a\n mSER33:catalyzes the first step in serine biosynthesis; isozyme of \nSER3,3-phosphoglycerate dehydrogenase,enzyme activity of 3P-\nglycerate dehydrogenase is decreased in null mutant compared\n to wildtype and abolished in ser3 ser33 double deletion mut\nant\n Cond398:Nitrogen_Depletion_4_h\n mMET22:Putative phosphatase gene involved in salt tolerance and met\nhionine biogenesis; halotolerance,3'(2')5'-bisphosphate nucl\neotidase,Methionine requiring; lacks 3'-phosphoadenylylsulfa\nte (PAPS) reductase activity; unable to grow on sulfate as s\nole sulfur source\n Cond294:Itraconazole\n Cond159:sir3\n Cond129:rip1\n Cond103:msu1\n Cond295:Lovastatin\n Cond265:ymr293c\n mYLR302C:Unknown ,, Unknown\n mFUN26:predicted membrane protein,,Null mutant is viable\n Cond299:Tunicamycin\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond938:2h\n Cond392:aa_starv_2_h\n mORT1:Mitochondrial integral membrane protein, ornithine transport\ner,,Null mutant is viable, arginine bradytroph\n mMMP1:S-MethylMethionine Permease,high affinity S-methylmethionine\n permease,Null mutant is viable but is unable to use S-methy\nlmethionine as a sulfur source\n Cond958:t0.5_g/r_ratio\n Cond703:gal10-gal\n
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity