Module number 1510




Database revision : gnsdb28.10
Date : Tue Feb 25 17:08:19 2003
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Cond128:rgt1\n mCIN8:Kinesin-related protein involved in establishment and mainte\nnance of mitotic spindle,,Null mutant is viable; cin8 dyn1 a\nnd cin8 kip1 double deletion mutants are inviable\n mSLK19:synthetic lethal KAR3,leucine zipper (putative),Null mutant \nexibits long astral microtubules, short spindles, bypass mei\nosis I, partial mitotic arrest; synthetic lethal with kar3*,\n loss of both produces mitotic arrest\n Cond278:CDC42(tetpromoter)\n mMDM32:Unknown ,, Unknown\n Cond130:rml2(**13)\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond670:DES459_(mec1)_-_mock_irradiation_-_5_min\n mYGR228W:Unknown ,, Unknown\n mKAR3:kinesin-like nuclear fusion protein,kinesin-like nuclear fus\nion protein,Null mutant is viable, kar3 mutations prevent ka\nryogamy (nuclear fusion)\n Cond170:ste20(**11)\n mMLP1:involved in translocation of macromolecules between the nucl\neoplasm and the NPC,colied-coil protein (putative), similar \nto myosin and TPR,null mutant is viable; mlp1 mlp2 double mu\ntant is viable but exhibits decreased nuclear import\n Cond26:cka2\n Cond185:ubr2\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mOPY1:imparts Far- phenotype,,\n Cond73:gyp1\n mYNL224C:Unknown ,, Unknown\n Cond283:KAR2(tetpromoter)\n mSOV1:Synthesis Of Var,,Mutant is respiratory deficient\n Cond808:Na15'\n mRSM18:protein similar to bacterial ribosomal subunit S18,mitochond\nrial ribosome small subunit component,null is unable to grow\n on glycerol\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mYLR287C:Unknown ,, Unknown\n Calcin.Na:Genome-wide analysis of gene expression regulated by the cal\ncineurin/Crz1p signaling pathway in Saccharomyces cerevisiae\n. J Biol Chem. 2002 Aug 23;277(34):31079-88\n mAPG17:required for activation of Apg1 protein kinase,,Null mutant \nis viable and has defect in autophagy , required for activat\nion of Apg1 protein kinase\n mPEP3:vacuolar membrane protein,vacuolar membrane protein,Null mut\nant is viable, exhibits growth defects at 37 degrees celsius\n, exhibits vacuolar protein sorting and processing and defec\nts, exhibits decreased levels of protease A, protease B, and\n carboxylpeptidase Y antigens; decreased repressible alkalin\ne phosphatase activity; null mutants contain very few normal\n vacuolelike organelles; homozygous null mutants are sporula\ntion defective\n Cond681:DES460_genomic_DNA_vs._MHY26_(dun1)_genomic_DNA\n mYMR132C:Unknown ,, Unknown\n mYKL082C:Unknown ,, Unknown\n COMP.TE:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mMTG1:Unknown ,, Unknown\n mMAD1:coiled-coil protein involved in spindle-assembly checkpoint,\n,Null mutant is viable, benomyl sensitive\n
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Computational Genomics Lab, Tel-Aviv uniresity