Module number 1404




Database revision : gnsdb28.10
Date : Tue Feb 25 17:03:02 2003
How to read this figure?


mYPR109W:Unknown ,, Unknown\n Jelinski.Jelinski:Regulatory networks revealed by transcriptional profiling of\n damaged Saccharomyces cerevisiae cells: Rpn4 links base exc\nision repair with proteasomes. Mol Cell Biol. 2000 Nov;20(2\n1):8157-67.\n mTOS5:Hypothetical ORF,,\n mQRI1:UDP-N-acetylglucosamine pyrophosphorylase,UDP-N-acetylglucos\namine pyrophosphorylase,\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mHNT2:Fhit homolog, member of the histidine triad superfamily of n\nucleotide binding-proteins,,\n mYKL063C:Unknown ,, Unknown\n Cond913:(99i3)_S150-2B_YPD_NormInt\n mURE2:Nitrogen catabolite repression regulator that acts by inhibi\ntion of GLN3 in good nitrogen source. Altered form of Ure2p\n creates [URE3] prion.,glutathione transferase (putative) , \nprion , transcriptional regulator,Null mutant is viable but \nexhibits defects in nitrogen catabolite repression (NCR), an\nd null mutant diploids are defective in pseudohyphal growth \nand display an increased incidence of random bud patterns.\n mCRZ1:calcineurin responsive zinc-finger,transcription factor (put\native),Null mutant is viable\n mEMP47:47 kDa type I transmembrane protein localized to the Golgi,4\n7 kDa type I transmembrane protein localized to the Golgi,Nu\nll mutant is viable\n Cond883:5\n mRPB4:fourth-largest subunit of RNA polymerase II,RNA polymerase I\nI fourth largest subunit,Null mutant is viable, rbp4 mutants\n are heat and cold sensitive, exhibit slow growth at interme\ndiate temperatures\n Cond898:RPN4\n Cond872:Zero1\n mEND3:Required for endocytosis and organization of the cytoskeleto\nn,,Null mutant is viable and defective in endocytosis\n Cond889:4NQO_2\n mSRB5:subunit of RNA polymerase II holoenzyme/mediator complex,RNA\n polymerase II holoenzyme/mediator subunit,Null mutant is vi\nable\n mMSO1:multicopy suppressor of sec1; small hydrophilic protein, enr\niched in microsomal membrane fraction, interacts with Sec1p,\n,Null mutant is viable, exhibits accumulation of secretory v\nesicles in the bud; mso1 null mutants exhibit double mutant \ninviability in combinaiton with sec1, sec2, and sec4 mutants\n COMP.:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond759:Heat_0'_(B)\n mCSE2:Protein required for accurate mitotic chromosome segregation\n,RNA polymerase II mediator subcomplex component,Null mutant\n is viable, accumulates large-budded cells, results in signi\nficant increase in chromosome missegregation, slower growth,\n and defective meiosis\n mYKL206C:Unknown ,, Unknown\n mMGT1:6-O-methylguanine-DNA methylase,6-O-methylguanine-DNA methyl\nase,Null mutant is viable, sensitive to alkylation induced k\nilling and mutation\n Cond897:STATMMS\n Cond888:MNNG_2\n Cond894:G2\n mSCP1:homolog of chicken calponin, thus the name S. cerevisiae Cal\nPonin,calponin homolog,Null mutant is viable and shows no ap\nparent phenotype\n mRPN12:Part of 26S proteasome complex that may activate Cdc28p,32-3\n4 kDa protein,Null mutant is inviable; nin1-1 mutant is temp\nerature-sensitive mutant that shows i) higher rates of recom\nbination and chromosome and plasmid loss; ii) greater sensit\nivity to UV irradiation; iii) at restrictive temperature, ar\nrest in G2, failure to activate histone H1 kinase, and accum\nulation of polyubiquinated proteins\n mRPN3:proteasome subunit,26S proteasome regulatory module componen\nt , similar to human p58 subunit,Null mutant is inviable. RP\nN3 is a high copy suppressor of the nin1-1 temperature sensi\ntive phenotype\n mHRB1:an ORF of unknown function located in a centromeric region d\nuplicated between chromosomes III and XIV,hypothetical RNA-b\ninding protein,\n Cond893:SMMS\n mYAF9:Yeast homolog of the human leukemogenic protein AF9; member \nof a large protein complex,,Null mutant is viable\n mRPN8:Regulatory Particle Non-ATPase, homolog of mammalian proteas\nomal subunit S12/p40,proteasome regulatory particle subunit,\n mSPP1:YPL138C,,\n mYDR131C:Unknown ,, Unknown\n Cond914:(99i2)_S150-2B_YPGL+G_NormInt\n mNHP10:Non-Histone Protein 10,HMG1-box containing protein,null muta\nnt is viable and has normal growth rate\n Y-Stre.Heat:Remodeling of yeast genome expression in response to environ\nmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37.\n mSEC9:Putative t-SNARE of the plasma membrane,t-SNARE (putative),A\nn uncharacterized allele accumulates 100nm secretory vesicle\ns and berkeley bodies and is defective in proteint transport\n to the cell surface. The sec9-4 allele has diploid-specific\n bud site selection defects.\n Cond895:G2MMS\n mGLC8:Homolog of mammalian protein phosphatase inhibitor 2,protein\n phosphatase 1 (Glc7p) regulator,Null mutant is viable; dele\ntion of glc8 suppresses phenotypes of ipl1 and glc7 mutants\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n Cond882:zero3\n Cond644:DES459_(mec1-)_+_0.02%_MMS_-_60_min\n Cond877:MMS\n Cond875:60min\n Cond886:g-ray\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mCAF4:CCR4 associated factor,CCR4 transcriptional complex componen\nt,Null mutant is viable\n mYHR192W:Unknown ,, Unknown\n mGLO2:Cytoplasmic glyoxylase-II,glyoxylase-II,Null mutant is viabl\ne but shows increased sensitivity to methylglyoxal\n mYFR003C:Unknown ,, Unknown\n mVPS60:vacuolar protein sorting (putative),,Null mutant is viable b\nut a class E vps mutant (missorts vacuolar hydrolases and ac\ncumulates late endosomal compartment).\n Cond73:gyp1\n mFAD1:Flavin adenine dinucleotide (FAD) synthetase, which performs\n second step in synthesis of FAD from riboflavin,FAD synthet\nase,Null mutant is inviable\n mVPS63:Unknown ,, Unknown\n Cond885:20\n mMAI1:Unknown ,, Unknown\n Cond645:DES459_(mec1-)_+_0.02%_MMS_-_90_min\n Cond891:G1MMS\n mCCL1:essential for cell proliferation,TFIIK subunit, a subcomplex\n of transcription factor TFIIH , cyclin,Null mutant is invia\nble\n mUFE1:t-SNARE that resides on the endoplasmic reticulum and mediat\nes retrograde traffic from the Golgi complex,t-SNARE (ER),Nu\nll mutant is inviable\n mVPS5:vacuolar Protein Sorting Defective; Golgi retention and vacu\nolar protein sorting,simialr to sorting nexin I,Null mutant \nis viable, missort and secrete soluble vacuolar proteins, co\nntain fragmented vacuoles and mislocalize carboxypepsidase a\nnd Vps10p.\n mCSN12:Unknown ,, Unknown\n mPNG1:de-N-glycosylation enzyme,peptide:N-glycanase,Null mutant is\n viable and shows no growth or viability defect under experi\nmental conditions\n mNKP1:Unknown ,, Unknown\n Cond643:DES459_(mec1-)_+_0.02%_MMS_-_45_min\n Cond641:DES459_(mec1-)_+_0.02%_MMS_-_15_min\n Cond884:10\n mBET4:catalyzes prenylation of Ypt1p (as a subunit of PGGTase-II),\ngeranylgeranyltransferase type II alpha subunit (PGGTase-II,\n alpha subunit),\n
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity