Module number 1312




Database revision : gnsdb28.10
Date : Tue Feb 25 17:46:14 2003
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mYCR090C:Unknown ,, Unknown\n mERG12:mevalonate catabolism,mevalonate kinase,Null mutant is invia\nble and unable to grow vegetatively or germinate spores; mut\nants exhibit increased mitotic stability of plasmids with we\nak ARS elements.\n mTRP2:anthranilate synthase Component I,anthranilate synthase comp\nonent I,tryptophan requiring\n mSAM2:methionine biosynthesis regulation,,Null mutant is viable\n mHCR1:High Copy suppressor of RPG1,,viable\n Cond45:ecm1(**3)\n Meiosis.Series0:The core meiotic transcriptome in budding yeasts. Nat Genet\n. 2000 Dec;26(4):415-23.\n Cond918:1h\n mCIT2:non-mitochondrial citrate synthase,citrate synthase,Null mut\nant is viable; disruption of both CIT1 and CIT2 result in gl\nutamate auxotrophy and poor growth on rich medium containing\n lactate.\n mUBP10:involved in telomeric silencing,ubiquitin-processing proteas\ne (putative),Null mutant is viable, exhibits decreased telom\neric silencing; UBP10(DOT4) overexpression reduces silencing\n at the HM, rDNA, and telomeric loci\n COMP.KO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n GCR1.gcr1:Understanding the growth phenotype of the yeast gcr1 mutant \nin terms of global genomic expression patterns. J Bacteriol\n. 2000 Sep;182(17):4970-8.\n mMATALPHA2:Homeobox-domain containing protein which, in haploid cells, \nacts with MCM1 to repress a-specific genes. In diploid cells\n alpha2 acts together with a1 to repress transcription of ha\nploid-specific genes.,,\n mIMD2:IMP Dehydrogenase,IMP dehydrogenase homolog,\n Cond913:(99i3)_S150-2B_YPD_NormInt\n Cond26:cka2\n SGD.GO:Functional classification via a compendium of knockouts. Hug\nes et.al., cell 2000.\n mSCP160:May be required during cell division for faithful partitioni\nng of the ER-nuclear envelope membranes, involved in control\n of mitotic chromsome transmission,,Null mutant is viable, b\nut exhibits decreased viability, abnormal morphology, and in\ncreased DNA content.\n mBFR1:Multicopy suppressor of BFA (Brefeldin A)-induced lethality;\n implicated in secretion and nuclear segregation,,Null mutan\nt is viable; increase in cell ploidy; defective in nuclear s\negregation, bud formation, cytokinesis, and nuclear spindle \nformation\n mTOP1:topoisomerase I,topoisomerase I,Null mutant is viable\n mRFC2:RFC is a DNA binding protein and ATPase that acts as a proce\nssivity factor for DNA polymerases delta and epsilon and loa\nds proliferating cell nuclear antigen (PCNA) on DNA,replicat\nion factor C subunit 2 , similar to human RFC 37 kDa subunit\n,Null mutant is inviable\n mNCP1:NADP-cytochrome P450 reductase,NADP-cytochrome P450 reductas\ne,Null mutant is viable\n mYNL224C:Unknown ,, Unknown\n mHNM1:choline transport protein; may also control uptake of nitrog\nen mustard,transporter (permease) for choline and nitrogen m\nustard; share homology with UGA4,Null mutant is viable, but \nhyper-resistant to nitrogen mustard; ctr1,cho1 double null i\ns inviable\n mYCR087W:Unknown ,, Unknown\n mVMA5:42 kDa subunit of V1 sector,V1 sector hydrophilic subunit C \n, vacuolar ATPase V1 domain subunit C (42 kDa) , vacuolar H-\nATPase , V1 sector hydrophilic subunit C , vacuolar ATPase V\n1 domain subunit C (42 kDa) , vacuolar H-ATPase,Null mutant \nis viable; certain vma5 mutations show allele-specific synth\netic lethality with cdc24-ls mutants\n mDCW1:Unknown ,, Unknown\n mKRR1:Involved in cell division and spore germination,,Null mutant\n is inviable\n mPRY3:Pathogen Related in Sc, contains homology to the plant PR-1 \nclass of pathogen related proteins. The protein sequence is \nover 60% identical with the Pry2p & Pry3p over 145 resid. PR\nY1 is >35% identical (50% similar) to tobacco PR-1c protein.\n,,\n mPAT1:Necessary for accurate chromosome transmission during cell; \nInvolved in mRNA turnover,,Null mutant is viable; slow growt\nh rate, reduced fidelity of chromosome segregation during bo\nth mitosis and meiosis; slower rate of deadenylation-depende\nnt decapping of mRNAs and transcript-specific effects on mRN\nA decay rates. \n mYCR095C:Unknown ,, Unknown\n mTHR4:threonine synthase,threonine synthase,threonine requiring\n mTUP1:general repressor of transcription (with Cyc8p); mediates gl\nucose repression,glucose repression regulatory protein, exhi\nbits similarity to beta subunits of G proteins,Null mutant i\ns viable; exhibits flocculent colony morphology\n mNFS1:NifS-like protein,,Null mutant is inviable; spl1-1 mutant al\nlele affects tRNA splicing\n Cond937:t=0\n mYCR023C:Unknown ,, Unknown\n Cond920:3h\n Cond274:yor080w(**3)\n mYCL063W:Unknown ,, Unknown\n Cond938:2h\n mMAK32:Protein necessary for structural stability of L-A double-str\nanded RNA-containing particles,,\n mRER1:Protein involved in retention of membrane proteins, includin\ng Sec12p, in the ER; localized to Golgi, where it may functi\non in returning membrane proteins to the ER,,Null mutant is \nviable and shows mislocalization of transmembrane proteins t\nhat are normally retained in the early secretory compartment\ns\n mLCB1:Involved in sphingolipid biosynthesis; may catalyze the firs\nt step in biosynthesis of long-chain sphingolipids,serine pa\nlmitoyltransferase component (putative),Null mutant is viabl\ne; auxotrophic for long-chain component of sphingolipids; ho\nmozygous lcb1 diploids fail to sporulate\n mARC1:associated with tRNA and amino acyl-tRNA synthetases; has af\nfinity for quadruplex nucleic acids,,Null mutant is viable, \nleads to slow growth and reduced MetRS activity; arc1- mutan\nts are synthetic lethals and are complemented by the genes f\nor methionyl-tRNA and glutamyl-tRNA synthetase.\n Cond939:4h\n
this is an automaticly generated SAMBA report
Computational Genomics Lab, Tel-Aviv uniresity